Synthesis of the metabolites of a free radical scavenger edaravone (MCI-186, Radicut).

abstract：OBJECTIVES:To assess the advantage of a protein-bound cobalamin absorption test (PBAT) over the Schilling test in patients with suspected cobalamin (vitamin B12) malabsorption. DESIGN:Clinical study of consecutive patients referred from primary care units, medical and neurological clinics. SETTING:The catchment area ...

journal_title：Redox report : communications in free radical research

authors： Guo Q,Packer L

更新日期：1999-01-01 00:00:00

abstract：:Muscle injuries represent a large number of professional and recreational sports injuries. Muscle strains habitually occur after an eccentric contraction, which often leads to an injury located in the myotendinous junction. Treatment varies widely, depending on the severity of the trauma, but has remained limited most...

journal_title：Redox report : communications in free radical research

authors： Kamat JP,Devasagayam TP

更新日期：1999-01-01 00:00:00

abstract：:Malaria causes significant morbidity and mortality world-wide. Both asymptomatic and symptomatic malarial infections cause immune depression, which predisposes the host to infection with other microorganisms. Specific clinical investigations have shown, for example, that those with malaria-attributable anaemia are par...

journal_title：Redox report : communications in free radical research

authors： Hite DR,Auh C,Scandalios JG

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Few treatments are available for isolated pulmonary hypertension (PHT), which has a high morbidity and mortality. This trial was designed to assess the hemodynamic effects of bosentan, an endothelin receptor antagonist, in patients with PHT, in which local overproduction of endothelin-1 (ET-1) is thought to ...

journal_title：Redox report : communications in free radical research

authors： Record IR,Jannes M

更新日期：2000-01-01 00:00:00

abstract：:The distribution of repetitive sequences, or microsatellites, formed by either one or two base pairs and longer than eight units, has been studied in almost 1 Mb of the sequenced Arabidopsis thaliana genome. Except for those formed by only G and C residues, the repetitions are more abundant in the Arabidopsis genome t...

journal_title：Redox report : communications in free radical research

authors： Grant RS,Naif H,Espinosa M,Kapoor V

更新日期：2000-01-01 00:00:00

abstract：:We use Data Envelopment Analysis (DEA) to measure the relative technical efficiencies of 164 HMOs licensed to practice in the United States in 1995 with data collected from the American Association of Health Plans. Health care output measures used in the analysis are the number of commercial, Medicare and Medicaid liv...

journal_title：Redox report : communications in free radical research

authors： Thomas EL,Jefferson MM,Learn DB,King CC,Dabbous MK

更新日期：2000-01-01 00:00:00

abstract：:In order to isolate and characterize new strawberry-associated bacteria antagonistic to the soil-borne pathogenic fungus Verticillium dahliae Kleb., rhizobacterial populations from two different strawberry species, Greenish Strawberry (Fragaria viridis) and Garden Strawberry (F. x ananassa) obtained after plating onto...

journal_title：Redox report : communications in free radical research

authors： Kwok JC,Richardson DR

更新日期：2000-01-01 00:00:00

abstract：:Estrogens are potent neuroprotective compounds in a variety of animal and cell culture models, and data indicate that estrogen receptor (ER)-mediated gene transcription is not required for some of these effects. To further address the requirement for an ER in estrogen enhancement of neuronal survival, we assessed the ...

journal_title：Redox report : communications in free radical research

authors： Touati D

更新日期：2000-01-01 00:00:00

abstract：:Epidemiological surveys show a large variation of type 2 diabetes (DT2) prevalence from one country to another, suggesting ethnic discrepancies in insulin sensitivity. Many data seem to confirm this hypothesis. We will show them while concentrating on data provided by surveys performed in French-speaking countries. Th...

journal_title：Redox report : communications in free radical research

authors： Madon PS

更新日期：2001-01-01 00:00:00

abstract：:IL-12 is a heterodimeric cytokine that plays a central role in cell-mediated immunity. We cloned complete cDNAs of guinea pig homologues of IL-12 p35 and p40 subunits, and compared their functional properties with human IL-12. Both p35 and p40 mRNA were constitutively expressed in the testis and peritoneal macrophages...

journal_title：Redox report : communications in free radical research

authors： Mendz GL,Trend MA

更新日期：2001-01-01 00:00:00

abstract：:Total body potassium may be predicted from height, weight, and age by TBKmmol = 30.83 Hcm + 18.05 Wkg - 11 (ageyr - 20) - 3034. This equation, based on measurements of 31 men, has been compared with others in the literature. Prediction of 24-hr creatinine (CR), excretion derived from 33 control adults whose excretion ...

journal_title：Redox report : communications in free radical research

authors： Koppenol WH

更新日期：2001-01-01 00:00:00

abstract：:There is conflicting information about gender differences in presentation, treatment, and outcome after acute ST elevation myocardial infarction (STEMI) in the era of thrombolytic therapy and primary percutaneous coronary intervention. From June 1994 to January 1997, we enrolled 6,067 consecutive patients with STEMI a...

journal_title：Redox report : communications in free radical research

authors： Koppenol WH

更新日期：2001-01-01 00:00:00

abstract：:There is conflicting information about gender differences in presentation, treatment, and outcome after acute ST elevation myocardial infarction (STEMI) in the era of thrombolytic therapy and primary percutaneous coronary intervention. From June 1994 to January 1997, we enrolled 6,067 consecutive patients with STEMI a...

journal_title：Redox report : communications in free radical research

authors： Hunt NH,Driussi C,Sai-Kiang L

更新日期：2001-01-01 00:00:00

abstract：:Ultrasonography is an excellent tool for the study of the anatomy of the human liver. This article shows, with the help of sonographic views along the long axis of portal and hepatic veins, and the different landmarks of the liver, how to delineate the eight segments of the liver. Doppler examination allows indentific...

journal_title：Redox report : communications in free radical research

authors： Santosh Kumar S,Priyadarsini KI,Sainis KB

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Colorectal stents are being used for palliation and as a 'bridge to surgery' in obstructing colorectal cancers. METHODS:A systematic review of the published data on stenting for the treatment of colorectal obstruction was carried out by searching Medline and other online databases for the period from Januar...

journal_title：Redox report : communications in free radical research

authors： Subramanian M,Chintalwar GJ,Chattopadhyay S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Colorectal stents are being used for palliation and as a 'bridge to surgery' in obstructing colorectal cancers. METHODS:A systematic review of the published data on stenting for the treatment of colorectal obstruction was carried out by searching Medline and other online databases for the period from Januar...

journal_title：Redox report : communications in free radical research

authors： Kim SY,Kim EJ,Park JW

更新日期：2002-01-01 00:00:00

abstract：:Bradyrhizobium japonicum can form a N2-fixing symbiosis with compatible leguminous plants. It can also act as a plant-growth promoting rhizobacterium (PGPR) for non-legume plants, possibly through production of lipo-chitooligosaccharides (LCOs), which should have the ability to induce disease resistance responses in p...

journal_title：Redox report : communications in free radical research

authors： Toyokuni S

更新日期：2002-01-01 00:00:00

abstract：:Inflammation is thought to be one of the major contributors to carcinogenesis. Accumulated studies in this field revealed that free radicals produced by inflammatory cells not only cause direct damage to DNA but also exert indirect effects such as de-regulation of cell proliferation and apoptosis, stimulation of angio...

journal_title：Redox report : communications in free radical research

authors： Okada F

更新日期：2002-01-01 00:00:00

abstract：:The genetic polymorphism of haptoglobin (Hp) is an independent risk factor in the pathogenesis of atherosclerosis, a condition in which decreased resistance to in vitro oxidation of LDL-cholesterol is observed. We hypothesised that the Hp polymorphism is one of the factors modulating the resistance to Cu(2+)-induced o...

journal_title：Redox report : communications in free radical research

authors： Bernard D,Christophe A,Delanghe J,Langlois M,De Buyzere M,Comhaire F

更新日期：2003-01-01 00:00:00

abstract：:Neutrophil activation and tumor necrosis factor-alpha (TNF-alpha) induction play a critical role in ischemia-reperfusion-induced intestinal inflammation. Peroxisome proliferator-activated receptor-gamma (PPAR-gamma), a member of the nuclear hormone receptor superfamily, has recently been implicated as a regulator of i...

journal_title：Redox report : communications in free radical research

authors： Naito Y,Takagi T,Uchiyama K,Handa O,Tomatsuri N,Imamoto E,Kokura S,Ichikawa H,Yoshida N,Yoshikawa T

更新日期：2002-01-01 00:00:00

abstract：:The ability of proteins to protect model liposome membranes from oxidation by hydroxyl and peroxyl free radicals was investigated. ...

journal_title：Redox report : communications in free radical research

authors： Tweeddale H,Gebicki JM

更新日期：2002-01-01 00:00:00

abstract：:The chemopreventive potential of cycloartenol on benzoyl peroxide and UVB radiation-induced cutaneous tumor promotion markers and oxidative stress in murine skin is assessed. Benzoyl peroxide treatment (20 mg/animal/0.2 ml acetone) and UVB radiation (0.420 J/m(2)/s) caused a decrease in the activities of cutaneous ant...

journal_title：Redox report : communications in free radical research

authors： Sultana S,Alam A,Khan N,Sharma S

更新日期：2003-01-01 00:00:00

abstract：:The effect of prior hyperthermia on UV-induced oxidative stress was studied in human skin fibroblasts. UV radiation alone induced an increased release of superoxide anions and increased lipid peroxidation in skin fibroblasts accompanied by a rise in catalase and superoxide dismutase activities. Hyperthermia was found ...

journal_title：Redox report : communications in free radical research

authors： Jones SA,McArdle A,McArdle F,Jack CI,Jackson MJ

更新日期：2003-01-01 00:00:00

abstract：:Methylene blue has intrinsic antimalarial activity and it can act as a chloroquine sensitizer. In addition, methylene blue must be considered for preventing methemoglobinemia, a serious complication of malarial anemia. As an antiparasitic agent, methylene blue is pleiotropic: it interferes with hemoglobin and heme met...

journal_title：Redox report : communications in free radical research

authors： Schirmer RH,Coulibaly B,Stich A,Scheiwein M,Merkle H,Eubel J,Becker K,Becher H,Müller O,Zich T,Schiek W,Kouyaté B

更新日期：2003-01-01 00:00:00

abstract：:The recent completion of the genome sequence of Plasmodium falciparum 3D7 provides the foundation for genome-wide analysis of the parasite. In addition to DNA and gene sequence data, postgenomic methods including microarray-based transcript profiling and high-throughput proteomics are now accessible to Plasmodium rese...

journal_title：Redox report : communications in free radical research

authors： Fraunholz MJ,Roos DS

更新日期：2003-01-01 00:00:00

abstract：:Conflicting evidence exists as to whether nitric oxide expresses damaging/inflammatory or antioxidant/anti-inflammatory properties. Data presented in this review indicate that in vitro or in vivo exposure to selected environmental or occupational agents, such as asbestos, silica, ozone or lipopolysaccharide, can resul...

journal_title：Redox report : communications in free radical research

authors： Zeidler PC,Castranova V

更新日期：2004-01-01 00:00:00

abstract：:Albendazole (ABZ) and mebendazole (MBZ) are two benzimidazole-derived drugs that show remarkable antihelmintic activity and are widely used in the treatment and control of helminths. Some antihelmintic drugs seem to act through the deleterious generation of reactive oxygen and nitrogen species (ROS and RNS, respective...

journal_title：Redox report : communications in free radical research

authors： Locatelli C,Pedrosa RC,De Bem AF,Creczynski-Pasa TB,Cordova CA,Wilhelm-Filho D

更新日期：2004-01-01 00:00:00

abstract：:Oxidative stress is the hallmark of various chronic inflammatory lung diseases. Increased concentrations of reactive oxygen species (ROS) in the lungs of such patients are reflected by elevated concentrations of oxidative stress markers in the breath, airways, lung tissue and blood. Traditionally, the measurement of t...

journal_title：Redox report : communications in free radical research

authors： Rahman I,Biswas SK

更新日期：2004-01-01 00:00:00

abstract：:Benzylhexadecyl dimethylammonium chloride (BHDC) and sodium bis(2-ethylhexyl) sulfosuccinate (AOT) water-in-oil micro-emulsions were employed to study the influence of medium heterogeneity on singlet molecular oxygen [O(2)((1)Delta(g))]-mediated degradation of 1-hydroxynaphthalene (1-OHN) and 2-hydroxynaphthalene (2-O...

journal_title：Redox report : communications in free radical research

authors： Luiz M,Biasutti MA,García NA

更新日期：2004-01-01 00:00:00

abstract：:The kinetics and mechanistic aspects of the riboflavin-photosensitised oxidation of the topically administrable ophthalmic drugs Timolol (Tim) and Pindolol (Pin) were investigated in water-MeOH (9:1, v/v) solution employing light of wavelength > 400 nm. riboflavin, belonging to the vitamin B(2) complex, is a known hum...

journal_title：Redox report : communications in free radical research

authors： Criado S,García NA

更新日期：2004-01-01 00:00:00