Clinical Utility of Methylation-Specific Multiplex Ligation-Dependent Probe Amplification for the Diagnosis of Prader-Willi Syndrome and Angelman Syndrome.

abstract：BACKGROUND:Hepatitis B remains the most common transfusion-transmitted viral infection. We explored the current status of pre-transfusion screening and post-transfusion follow-up testing for hepatitis B virus (HBV) surface antigen (HBsAg) and antibodies (anti-HBs) in blood recipients from an area of high HBV endemicity...

journal_title：Annals of laboratory medicine

authors： Kim H,Hur M,Moon HW,Park CM,Cho JH,Park KS,Lee K,Chang S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Recent studies and case reports have shown that recombinant factor VIIa (rFVIIa) treatment is effective for reversing coagulopathy and reducing blood transfusion requirements in trauma patients with life-threatening hemorrhage. The purpose of this study is to evaluate the effect of rFVIIa treatment on clinic...

journal_title：Annals of laboratory medicine

authors： Koh YR,Cho SJ,Yeom SR,Chang CL,Lee EY,Son HC,Kim HH

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Chitotriosidase is an accepted marker of macrophage activation. In this study, we investigated serum chitotriosidase levels in pulmonary tuberculosis (PTB). METHODS:Forth-two patients with PTB and 30 healthy subjects were enrolled in the study. The radiological extent of PTB, radiological sequela after trea...

journal_title：Annals of laboratory medicine

authors： Cakır G,Gumus S,Ucar E,Kaya H,Tozkoparan E,Akgul EO,Karaman B,Deniz O,Kurt I,Ozkan M,Bilgic H

更新日期：2012-05-01 00:00:00

abstract：:Spondyloepiphyseal dysplasia (SED) comprises a heterogeneous group of skeletal dysplasias that primarily affect the epiphyses and vertebral bodies. Patients affected by SED usually exhibit short stature and experience early development of degenerative osteoarthritis. SED is subdivided into congenita and tarda forms ac...

journal_title：Annals of laboratory medicine

authors： Ryu H,Park J,Chae H,Kim M,Kim Y,Ok IY

更新日期：2012-05-01 00:00:00

abstract：:Numerical and structural chromosomal abnormalities are common in hematological malignancies. Near-triploidy (58-80 chromosomes) is a numerical abnormality observed in 3% of adult cases of acute lymphoblastic leukemia. Near-triploidy is rare in myeloid lineage hematologic malignancies and compared to near-triploidy in ...

journal_title：Annals of laboratory medicine

authors： Kim BR,Kim JE,Woo KS,Kim KH,Kim JM,Lee S,Shaffer LG,Han JY

更新日期：2012-07-01 00:00:00

abstract：:In recent years, there have been increasing reports of KPC-producing Klebsiella pneumoniae in Korea. The modified Hodge test can be used as a phenotypic screening test for class A carbapenamase (CAC)-producing clinical isolates; however, it does not distinguish between carbapenemase types. The confirmation of type of ...

journal_title：Annals of laboratory medicine

authors： Hong SS,Kim K,Huh JY,Jung B,Kang MS,Hong SG

更新日期：2012-09-01 00:00:00

abstract：:The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioMérieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.1%, and 97.3% for amphotericin B, fluconazole, voriconazole, and...

journal_title：Annals of laboratory medicine

authors： Jung SI,Shin JH,Choi HJ,Ju MY,Kim SH,Lee WG,Park YJ,Lee K,Korean Study Group for Candidemia.

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Interferon-γ (IFN-γ) plays a crucial role in Mycobacterium tuberculosis induced pleural responses. Interleukin (IL)-33 up-regulates the production of IFN-γ. We aimed to identify whether an association between pleural IL-33 levels and tuberculous pleurisy exists and determine its diagnostic value. METHODS:Pl...

journal_title：Annals of laboratory medicine

authors： Lee KS,Kim HR,Kwak S,Choi KH,Cho JH,Lee YJ,Lee MK,Lee JH,Park SD,Park DS

更新日期：2013-01-01 00:00:00

abstract：:Geosmithia argillacea, an anamorph of Talaromyces eburneus, is a thermophilic filamentous fungus that has a phenotype similar to that of the Penicillium species, except for the creamy-white colonies and cylindrical conidia. Recently, a new genus called Rasamsonia has been proposed, which is to accommodate the Talaromy...

journal_title：Annals of laboratory medicine

authors： Sohn JY,Jang MA,Lee JH,Park KS,Ki CS,Lee NY

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:At present, the clinical breakpoints (CBPs) of both fluconazole and voriconazole are available only for 3 common Candida species in the Clinical and Laboratory Standards Institute (CLSI) and the European Committee on Antimicrobial Susceptibility Testing (EUCAST) methods. Epidemiological cutoff values (ECVs) ...

journal_title：Annals of laboratory medicine

authors： Jang MJ,Shin JH,Lee WG,Kim MN,Lee K,Lee HS,Lee MK,Chang CL,Jang HC,Song ES,Kim SH,Shin MG,Suh SP,Ryang DW

更新日期：2013-05-01 00:00:00

abstract：:Ataxia-telangiectasia (A-T) is a rare autosomal recessive neurodegenerative disorder. It is characterized by early-onset, progressive cerebellar ataxia, oculomotor apraxia, choreoathetosis, conjunctival telangiectasias, immunodeficiency, and an increased risk of malignancy. Although A-T is known to be the most common ...

journal_title：Annals of laboratory medicine

authors： Huh HJ,Cho KH,Lee JE,Kwon MJ,Ki CS,Lee PH

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The Hb levels of prospective blood donors are usually determined using a finger prick test. A new noninvasive Hb device has the advantage of not causing any sampling pain. The purpose of this study was to evaluate the accuracy of the noninvasive Hb sensor and to compare its measurements with those of a curre...

journal_title：Annals of laboratory medicine

authors： Kim MJ,Park Q,Kim MH,Shin JW,Kim HO

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Active screening for vancomycin-resistant enterococci (VRE) using rectal specimens is recommended to limit the spread of antimicrobial resistance within certain high-risk populations. We evaluated the diagnostic performance of Vancomycin Resistance 3 Multiplexed Tandem PCR assay (AusDiagnostics, Australia), ...

journal_title：Annals of laboratory medicine

authors： Cekin Y,Erman Daloğlu A,Oğünç D,Ozhak Baysan B,Dağlar D,Inan D,Mutlu D,Ongüt G,Colak D

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Human neutrophil antigens (HNAs) are involved in autoimmune and alloimmune neutropenia and transfusion-related acute lung injury. The HNA-1 system is important in immunogenetics, and allele frequencies have been described in different populations. This study investigated the frequency of FCGR3B alleles encod...

journal_title：Annals of laboratory medicine

authors： Kaset C,Leetrakool N,Intharanut K,Nathalang O

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Early laboratory detection of Mycobacterium tuberculosis is crucial for controlling tuberculosis. We developed a hydrogel mycobacterial culture method that retains the advantages of both solid and liquid methods in terms of speed, cost, and efficiency. METHODS:Mycobacterium bovis bacillus Calmette-Guérin (B...

journal_title：Annals of laboratory medicine

authors： Jang MH,Kim SY,Kim CK,Hwang SH,Park BK,Kim SS,Lee EY,Chang CL

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Dysfunctional natural anticoagulant systems enhance intravascular fibrin formation in disseminated intravascular coagulation (DIC), and plasma levels of natural anti coagulants can be used in the diagnosis and prognosis of DIC. Herein, the diagnostic value of 4 natural anticoagulants was assessed, and the pr...

journal_title：Annals of laboratory medicine

authors： Choi Q,Hong KH,Kim JE,Kim HK

更新日期：2014-03-01 00:00:00

abstract：:We evaluated the new C. DIFF QUIK CHEK COMPLETE (CD COMPLETE; TechLab, USA), which is a rapid membrane enzyme immunoassay that uses a combination of glutamate dehydrogenase (GDH) antigen and toxin A and B detection. A total of 608 consecutive loose stool specimens collected from the patients with suspected Clostridium...

journal_title：Annals of laboratory medicine

authors： Kim H,Kim WH,Kim M,Jeong SH,Lee K

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:We evaluated the performance of two different array-based techniques, a bead-based multiplex genotyping method (LQ; digene HPV Genotyping LQ Test, QIAGEN, Germany) and a DNA chip-based method using peptide nucleic acid probes (PANArray; PANArray HPV Genotyping Chip, Panagene, Korea), for detection of human p...

journal_title：Annals of laboratory medicine

authors： Park KS,Kim JY,Ki CS,Lee NY

更新日期：2014-07-01 00:00:00

abstract：:We performed customer satisfaction surveys for physicians and nurses regarding clinical laboratory services, and for outpatients who used phlebotomy services at a tertiary care unit level to evaluate our clinical laboratory and phlebotomy services. Thus, we wish to share our experiences with the customer satisfaction ...

journal_title：Annals of laboratory medicine

authors： Koh YR,Kim SY,Kim IS,Chang CL,Lee EY,Son HC,Kim HH

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Acinetobacter species are the leading cause of bloodstream infection (BSI), but their correct identification is challenging. We evaluated the matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS)-based VITEK MS (bioMérieux, France), and two automated systems, VITEK 2 (bi...

journal_title：Annals of laboratory medicine

authors： Lee SY,Shin JH,Kim SH,Shin MG,Suh SP,Ryang DW

更新日期：2015-01-01 00:00:00

abstract：:Intermediate-resolution HLA-DQ typing has gained importance in organ transplantation recently. We evaluated the performance of the LIFECODES HLA-DQB1 typing kit (Immucor, USA) using sequence-specific oligonucleotide (SSO) probe and Luminex platform (Luminex Corp., USA) on 100 samples tested by sequence-based typing (S...

journal_title：Annals of laboratory medicine

authors： Roh EY,In JW,Shin S,Yoon JH,Park KU,Song EY

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Viridans group streptococci (VGS) are both commensal microbes and potential pathogens. Increasing resistance to penicillin in VGS is an ongoing issue in the clinical environment. We investigated the difference in susceptibility and resistance to penicillin among various VGS species. METHODS:In total 1,448 V...

journal_title：Annals of laboratory medicine

authors： Chun S,Huh HJ,Lee NY

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Mutations in the transforming growth factor β-induced gene (TGFBI) are major causes of genetic corneal dystrophies (CDs), which can be grouped into TGFBI CDs. Although a few studies have reported the clinical and genetic features of Korean patients with TGFBI CD, no data are available regarding the frequency...

journal_title：Annals of laboratory medicine

authors： Song JS,Lim DH,Chung ES,Chung TY,Ki CS

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Streptococcus pneumoniae causes pneumonia, sepsis, and meningitis. This study aimed to investigate the clinical characteristics of mucoid and non-mucoid isolates of S. pneumoniae, and to explore the relationship between the isolate phenotypes and their antibiotic susceptibility. METHODS:Clinical isolates fr...

journal_title：Annals of laboratory medicine

authors： Ogihara S,Saito R,Akikura T,Iwama A,Adachi Y,Kaji D,Kakinuma K,Takahashi H

更新日期：2015-07-01 00:00:00

abstract：:CYP21A2 mutation analysis of congenital adrenal hyperplasia (CAH) is challenging because of the genomic presence of a homologous CYP21A2 pseudogene and the significant incidence of pseudogene conversion and large deletions. The objective of this study was to accurately analyze the CYP21A2 genotype in Korean CAH patien...

journal_title：Annals of laboratory medicine

authors： Hong G,Park HD,Choi R,Jin DK,Kim JH,Ki CS,Lee SY,Song J,Kim JW

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:We aimed to determine the association between platelet indices including plateletcrit (PCT), mean platelet volume (MPV), platelet distribution width (PDW), and proteinuria associated with hypertension (HT) as well as the relative power of each to predict proteinuria. METHODS:The study included 223 patients ...

journal_title：Annals of laboratory medicine

authors： Ates I,Bulut M,Ozkayar N,Dede F

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The immature platelet fraction (IPF) reflects the degree of reticulated platelets. We evaluated performances of IPF as a biomarker for the discrimination of septic patients from non-septic patients and sepsis severity. METHODS:Total 312 patients admitted between March and July 2013 were enrolled and samples...

journal_title：Annals of laboratory medicine

authors： Park SH,Ha SO,Cho YU,Park CJ,Jang S,Hong SB

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Most cases with congenital hypothyroidism (CH) are usually sporadic, while about 20% of the cases are caused by genetic defects. Little information is available regarding the mutation incidence and genetic heterogeneity of CH in Koreans. We aimed to determine the mutation incidence of CH in newborn screening...

journal_title：Annals of laboratory medicine

authors： Park KJ,Park HK,Kim YJ,Lee KR,Park JH,Park JH,Park HD,Lee SY,Kim JW

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:We estimated the prevalence and clinical impact of heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA). The concordance between macromethod and glycopeptide resistance detection (GRD) E tests was determined. In addition, predictors of clinical outcomes in hospitalized patients with S. aureus ...

journal_title：Annals of laboratory medicine

authors： Koh YR,Kim KH,Chang CL,Yi J

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Glycated albumin (GA) is a better marker of short-term glycemic control than glycated hemoglobin (A1c). Dyslipidemia is the main cause of cardiovascular complications in diabetes mellitus (DM). Studies on the correlation of GA with lipid indices are sparse. We investigated the diagnostic utility of GA for DM...

journal_title：Annals of laboratory medicine

authors： Park S,Lee W,Chung HS,Hong KS

更新日期：2016-07-01 00:00:00