Abstract:
BACKGROUD:To evaluate the relationship between omentin-1 and benign prostatic hyperplasia (BPH). BPH is the most common urological disease in elderly men worldwide. Lower serum omentin-1 levels were reported to be negatively associated with the incidence of inflammation, diabetes, obesity and metabolic syndrome, which all play a role in the development of BPH. To the best of our knowledge, the relationship between omentin-1 and BPH has not been investigated previously. METHODS:A total of 70 males participated in this study, including forty patients diagnosed with BPH and thirty healthy males. The anthropometric measurements and the biochemical parameters were measured in this study. We evaluated serum omentin-1 levels and the correlation with those data. We also test the gene expression of IL-8, IL-18 in BPH group using the TURP tissues. RESULTS:The serum omentin-1 levels were lower in the BPH patients than in the control group (27.95 ± 4.18 versus 32.03 ± 5.46, p < 0.001). The general characteristics and biochemical parameters were investigated, and a negative correlation was found between serum omentin-1 levels and BMI in the BPH group (r = - 0.391, p = 0.013) as well as the whole group (r = - 0.457, p < 0.001). Multiple-factor binary regression analysis revealed that serum omentin-1was a protective factor of BPH development. Furthermore, lower serum omentin-1 levels were associated with higher mRNA expression of IL-8 or IL-18 in the BPH group. CONCLUSION:Omentin-1 may suppress the development of BPH and Lower serum omentin-1 levels in BPH patients might associated with higher prostate volume and higher IL-8 and IL-18 expression levels in their prostatic cells.
journal_name
BMC Uroljournal_title
BMC urologyauthors
He H,Wu S,Hao J,Wang L,Ai K,Zhu X,Xu R,Zhao X,Wang Y,Zhong Zdoi
10.1186/s12894-020-00623-4subject
Has Abstractpub_date
2020-05-06 00:00:00pages
52issue
1issn
1471-2490pii
10.1186/s12894-020-00623-4journal_volume
20pub_type
杂志文章相关文献
BMC Urology文献大全abstract:BACKGROUND:The management of emphysematous pyelonephritis (EPN) includes conservative medical treatment, percutaneous drainage, and surgical resection of the involved kidney. EPN with diabetic ketoacidosis(DKA) is very rare, in which the clinical management of refusing surgical drainage is inexperienced. CASE PRESENTA...
journal_title:BMC urology
pub_type: 杂志文章,评审
doi:10.1186/s12894-020-0575-0
更新日期:2020-01-29 00:00:00
abstract:BACKGROUND:Radical prostatectomy is the most common and effective treatment for localized prostate cancer. Unfortunately, radical prostatectomy is associated with urinary incontinence and has a significant negative impact on quality of life. Pelvic floor exercises are the most common non-invasive management strategy fo...
journal_title:BMC urology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12894-015-0088-4
更新日期:2015-09-16 00:00:00
abstract:BACKGROUND:To explore the additive effect of urinary incontinence, in people with comorbid depression, on health related quality of life. METHODS:Males and females, 15 to 95 years (n = 3010, response rate 70.2%) were interviewed face to face in the 1998 Autumn South Australian Health Omnibus Survey. RESULTS:Self-repo...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-13-11
更新日期:2013-02-16 00:00:00
abstract:BACKGROUND:Extracorporeal shockwave lithotripsy (ESWL) is the management of choice for renal stones 20 mm or smaller, with a stone clearance rate of up to 89%. The purpose of the present is to investigate the efficacy of a commercialised ESWL service, being performed as an outsourced treatment using a mobile lithotrips...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-017-0249-8
更新日期:2017-07-27 00:00:00
abstract:BACKGROUND:To review the possible mechanisms proposed to explain the etiology of 46, XX sex reversal by investigating the clinical characteristics and their relationships with chromosomal karyotype and the SRY(sex-determining region Y)gene. METHODS:Five untreated 46, XX patients with SRY-positive were referred for inf...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-14-70
更新日期:2014-08-28 00:00:00
abstract:BACKGROUND:To explore the feasibility and long-term outcomes of renal preservation in a retrospective cohort of patients with ureteral urothelial carcinoma undergoing total ureterectomy with ileal-ureteral substitution. METHODS:A retrospective review of the data from patients treated with total ureterectomy with ileal...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-018-0389-5
更新日期:2018-08-31 00:00:00
abstract:BACKGROUND:Many factors including vasoconstrictor agents can interfere with wound healing process. This study aimed to compare the histopathological outcome of injection of two sympathomimetic drugs used during urologic surgery, including phenylephrine and epinephrine, on the structure of spongy tissue and urethra in a...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-019-0483-3
更新日期:2019-06-20 00:00:00
abstract:BACKGROUND:We describe a detailed novel step-by-step approach for creation of an ileal neobladder and compare the outcomes with standart neobladder. METHODS:Between August 2009 and January 2016, 36 consecutive patients with bladder cancer underwent radical cystectomy and orthotopic urinary diversion with an ileal neob...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-018-0406-8
更新日期:2018-10-26 00:00:00
abstract:BACKGROUND:Wilms tumor is the most common renal tumor of childhood. Duplication of the inferior vena cava is an uncommon anomaly. In the present study, we present a case of Wilms tumor with the inferior vena cava duplication, which has not been reported previously. CASE PRESENTATION:A 14-month-old female presented wit...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-018-0401-0
更新日期:2018-10-19 00:00:00
abstract:BACKGROUND:To assess factors that can predict active surveillance (AS) failure on serial transrectal ultrasound guided biopsies in patients with low-risk prostate cancer. METHODS:We evaluated the records of 144 consecutive patients enrolled in AS between 2007 and 2014 at a single academic institution. Low risk inclusi...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-019-0452-x
更新日期:2019-04-23 00:00:00
abstract:BACKGROUND:Spectrum effects refer to the phenomenon that test performance varies across subgroups of a population. When spectrum effects occur during diagnostic testing for cancer, difficult patient misdiagnoses can occur. Our objective was to evaluate the effect of test indication, age, gender, race, and smoking statu...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-016-0147-5
更新日期:2016-06-13 00:00:00
abstract:BACKGROUND:Over the last few years the number of flexible ureterorenoscopies, used for renal stone treatment, has risen steadily. This was associated with an increase in costs for maintenance and repair of the fragile ureterorenoscopes used. To overcome this problem single-use devices have been introduced to the market...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00624-3
更新日期:2020-05-18 00:00:00
abstract:BACKGROUND:Ureteral herniations are a rare occurrence, generally found incidentally on cross sectional imaging or during surgical intervention for unrelated processes. Several locations of ureteral herniations can occur including the inguinal, femoral, sciatic, obturator, and thoracic regions. While few reports of uret...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-017-0207-5
更新日期:2017-04-05 00:00:00
abstract::This review summarizes recent literature on advances regarding renal and ureteral calculi, with particular focus in areas of recent advances in the overall field of urolithiasis. Clinical management in everyday practice requires a complete understanding of the issues regarding metabolic evaluation and subgrouping of s...
journal_title:BMC urology
pub_type: 杂志文章,评审
doi:10.1186/1471-2490-13-10
更新日期:2013-02-16 00:00:00
abstract:BACKGROUND AND AIMS:It has been reported that Helicobacter pylori (HP) infection was more prevalent in infertile populations. HP infection could lead to decreased sperm parameters, and treating the HP infection could improve the quality of sperm. However, studies investigating the relationship between infertility and H...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00725-z
更新日期:2020-11-26 00:00:00
abstract:BACKGROUND:Urologists frequently encounter malignant ureteral obstruction (MUO) caused by advanced urological or non-urological malignant disease, but the treatment policy is unclear. The present study examined the risk factors for predicting ureteral stent failure in patients with MUO after ureteral stent insertion an...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-018-0346-3
更新日期:2018-05-08 00:00:00
abstract:BACKGROUND:Cystic renal cell carcinoma (CRCC) is relatively rare; CRCC is frequently misdiagnosed as a benign renal cyst. CRCC carries an excellent prognosis following surgical treatment. The aim of our study was to summarize the management of CRCC and to characterize the prognosis of affected patients. METHODS:A retr...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-14-87
更新日期:2014-11-07 00:00:00
abstract:BACKGROUND:The route of local and metastatic spread of testicular seminoma is well recognised and accepted. The spread is via lymphatics to the paraaortic nodes. CASE PRESENTATION:We present a case report of testicular seminoma in a 56 year old man with previously unreported histological findings. In this case seminom...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/1471-2490-6-5
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Neglected renal stones remain a major cause of morbidity in developing countries. They not only result in functional impairment of affected kidney, but also act as an important predisposing factor for development of urothelial neoplasms. It is not uncommon to miss an associated urothelial tumor in a patient ...
journal_title:BMC urology
pub_type: 杂志文章,评审
doi:10.1186/1471-2490-6-1
更新日期:2006-01-08 00:00:00
abstract:BACKGROUND:To investigate the factor structure, dimensionality and construct validity of the (5-item) PRAFAB questionnaire score in women with stress urinary incontinence (stress UI). METHODS:A cross validation study design was used in a cohort of 279 patients who were randomly divided into Sample A or B. Sample A was...
journal_title:BMC urology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2490-8-1
更新日期:2008-01-24 00:00:00
abstract:BACKGROUND:Chronic indwelling catheters may induce histologic changes within the bladder, and these changes are sometimes pre-malignant. There are many documented cases of squamous cell carcinoma associated with indwelling catheters, but only three cases of catheter-associated adenocarcinoma have been reported. In this...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-015-0112-8
更新日期:2015-12-03 00:00:00
abstract:BACKGROUND:Previous studies report association of contraceptives with moderate increase in urinary tract infection among sexually active premenopausal women. The aim of our study was to find out whether the use of hormonal contraceptives has any effect on microbiota of the vagina in the contraceptives users in Khairpur...
journal_title:BMC urology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2490-12-22
更新日期:2012-08-18 00:00:00
abstract:BACKGROUND:Bladder hyperthermic intracavitary chemotherapy (HIVEC) has good effectiveness for bladder cancer, but conventional HIVEC systems lack precision and convenient application. To test the safety of a new HIVEC device (BR-TRG-II-type) in pigs and to perform a preliminary clinical trial in patients with bladder c...
journal_title:BMC urology
pub_type: 临床试验,杂志文章
doi:10.1186/s12894-019-0543-8
更新日期:2019-12-03 00:00:00
abstract:BACKGROUND:Upper urinary tract stones is the most common diseases in urology. Percutaneous nephrolithotomy (PCNL) and ureteroscopic lithotripsy (fURL) are common treatment, but both their efficacy and safety are controversial. Thus we aim to evaluate the efficacy and safety of PCNL and fURL in the treatment of upper ur...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00677-4
更新日期:2020-07-25 00:00:00
abstract:BACKGROUND:To assess the prognostic value of the extent of positive surgical margins (PSM) following radical prostatectomy (RP) on biochemical recurrence (BR) with long-term follow-up. METHODS:This retrospective study analyzed 1275 RPs performed between January 1992 and December 2013 in two university centers in Marse...
journal_title:BMC urology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12894-019-0470-8
更新日期:2019-05-15 00:00:00
abstract:BACKGROUND:Polyorchidism is a congenital anomaly of the urogenital system and means more than two testes. It is a rare phenomenon, where there are no more than 200 reported cases in the literature. In this case, we report a 13-month year's old case with five testicles. CASE PRESENTATION:We report a rare five testicles...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00681-8
更新日期:2020-08-20 00:00:00
abstract:BACKGROUND:Pheochromocytoma (paraganglioma) of the urinary bladder is a rare tumor. Herein we sought to review the contemporary literature on pheochromocytomas of the urinary bladder in order to further illustrate the presentation, treatment options and outcomes of patients diagnosed with these tumors. METHODS:A compr...
journal_title:BMC urology
pub_type: 杂志文章,meta分析,评审
doi:10.1186/1471-2490-13-22
更新日期:2013-04-29 00:00:00
abstract:BACKGROUND:To determine risk factors for postoperative fever (POF) after retrograding intrarenal surgery (RIRS) and a nomogram for prediction of POF in patients undertaking RIRS has been developed based on the risk factors found. METHODS:This is a retrospective designed-study. A continuous cohort from a single-center ...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00620-7
更新日期:2020-05-06 00:00:00
abstract:BACKGROUND:To evaluate the role of free-hand transperineal targeted prostate biopsy using multiparametric magnetic resonance imaging-transrectal ultrasound (mpMRI-TRUS) fusion in Chinese men with repeated biopsy. METHODS:A total of 101 consecutive patients suspicious of prostate cancer (PCa) at the mpMRI scan and with...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-017-0241-3
更新日期:2017-07-05 00:00:00
abstract:BACKGROUND:Atraumatic renal pelvis rupture without pre-existing renal or ureteric pathology is an uncommon event. It is reported in the setting of acute urinary tract obstruction, most often secondary to ureteric calculi. Typical symptoms include acute flank pain and nausea, mimicking pyelonephritis or other causes of ...
journal_title:BMC urology
pub_type: 杂志文章
doi:10.1186/s12894-020-00669-4
更新日期:2020-07-13 00:00:00