Abstract:
BACKGROUND:The main objective of this study was to describe selected clinico-pathological characteristics of Oral Squamous Cell Carcinoma (OSCC) in Sri-Lanka. MATERIALS & METHODS:The study sample comprised of eight hundred and ninety six biopsies diagnosed as OSCC. The clinical and histopathological features were analyzed using the Chi-square test. RESULTS:Of the 896 biopsies, 801 were primary OSCCs, while 95 were recurrent OSCCs. Majority of the patients (78 %) were in the 5(th) to 7(th) decades of life and showed a male predilection. The buccal mucosa was the commonest site of primary OSCC comprising of 43 % of the sample. Of the primary OSCCs, with known TNM stage, 86 % were in stage 3&4 and majority (59 %) of stage 4 tumours showed tumour at one or more excision margins. Of the recurrent OSCC, 46 % developed their recurrences within one year of the excision of the primary tumour. CONCLUSION:In Sri-Lanka, OSCC is a major problem. Only half the patients had completely excised tumours (with clearance of >5 mm at all excision margins) at operation, and recurrences appeared early. This data should be considered in the future management policy of OSCC in Sri-Lanka.
journal_name
BMC Oral Healthjournal_title
BMC oral healthauthors
Jayasooriya PR,Pitakotuwage TN,Mendis BR,Lombardi Tdoi
10.1186/s12903-015-0139-ysubject
Has Abstractpub_date
2016-01-08 00:00:00pages
1issn
1472-6831pii
10.1186/s12903-015-0139-yjournal_volume
16pub_type
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