Abstract:
BACKGROUND:Considerable racial and socio-economic disparities exist in breast cancer. In spite of the existence of numerous evidence-based interventions (EBIs) aimed at reducing breast cancer screening barriers among the underserved, there is a lack of uptake or sub-optimal uptake of EBIs in community and clinical settings. This study evaluates a theoretically based, systematically designed implementation strategy to support adoption and implementation of a patient navigation-based intervention, called Peace of Mind Program (PMP), aimed at improving breast cancer screening among underserved women. METHODS/DESIGN:The PMP will be offered to federally qualified health centers and charity clinics in the Greater Houston area using a non-randomized stepped wedge design. Due to practical constraints of implementing and adopting in the real-world, randomization of start times and blinding will not be used. Any potential confounding or bias will be controlled in the analysis. Outcomes such as appointment adherence, patient referral to diagnostics, time to diagnostic referral, patient referral to treatment, time to treatment referral, and budget impact of the intervention will be assessed. Assessment of constructs from the consolidated framework for implementation research (CFIR) will be assessed during implementation and at the end of the study (sustainment) from each participating clinic. Data will be analyzed using descriptive statistics (chi-square tests) and generalized estimating equations (GEE). DISCUSSION:While parallel group randomized controlled trials (RCT) are considered the gold standard for evaluating EBI efficacy, withholding an effective EBI in practice can be both unethical and/or impractical. The stepped wedge design addresses this issue by enabling all clinics to eventually receive the EBI during the study and allowing each clinic to serve as its own control, while maintaining strong internal validity. We expect that the PMP will prove to be a feasible and successful strategy for reducing appointment no-shows in underserved women. TRIAL REGISTRATION: CLINICAL TRIALS REGISTRATION NUMBER:NCT02296177.
journal_name
Implement Scijournal_title
Implementation science : ISauthors
Highfield L,Rajan SS,Valerio MA,Walton G,Fernandez ME,Bartholomew LKdoi
10.1186/s13012-015-0334-xsubject
Has Abstractpub_date
2015-10-14 00:00:00pages
143issn
1748-5908pii
10.1186/s13012-015-0334-xjournal_volume
10pub_type
临床试验,杂志文章abstract:BACKGROUND:Adapting interventions that have worked elsewhere can save resources associated with developing new interventions for each specific context. While a developing body of evidence shows benefits of adapted interventions compared with interventions transported without adaptation, there are also examples of inter...
journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
pub_type: 杂志文章
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abstract:BACKGROUND:Large-scale implementation of evidence-based psychotherapies (EBPs) such as cognitive processing therapy (CPT) for posttraumatic stress disorder can have a tremendous impact on mental and physical health, healthcare utilization, and quality of life. While many mental health systems (MHS) have invested heavil...
journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
pub_type: 杂志文章
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
pub_type: 杂志文章
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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journal_title:Implementation science : IS
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