Abstract:
:To answer the need for the rigorous protection of biomedical data, we organized the Critical Assessment of Data Privacy and Protection initiative as a community effort to evaluate privacy-preserving dissemination techniques for biomedical data. We focused on the challenge of sharing aggregate human genomic data (e.g., allele frequencies) in a way that preserves the privacy of the data donors, without undermining the utility of genome-wide association studies (GWAS) or impeding their dissemination. Specifically, we designed two problems for disseminating the raw data and the analysis outcome, respectively, based on publicly available data from HapMap and from the Personal Genome Project. A total of six teams participated in the challenges. The final results were presented at a workshop of the iDASH (integrating Data for Analysis, 'anonymization,' and SHaring) National Center for Biomedical Computing. We report the results of the challenge and our findings about the current genome privacy protection techniques.
journal_name
BMC Med Inform Decis Makjournal_title
BMC medical informatics and decision makingauthors
Jiang X,Zhao Y,Wang X,Malin B,Wang S,Ohno-Machado L,Tang Hdoi
10.1186/1472-6947-14-S1-S1subject
Has Abstractpub_date
2014-01-01 00:00:00pages
S1issn
1472-6947pii
1472-6947-14-S1-S1journal_volume
14 Suppl 1pub_type
杂志文章abstract:BACKGROUND:Percutaneous coronary intervention (PCI) is the most commonly performed treatment for coronary atherosclerosis. It is associated with a higher incidence of repeat revascularization procedures compared to coronary artery bypass grafting surgery. Recent results indicate that PCI is only cost-effective for a su...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-015-0131-0
更新日期:2015-02-14 00:00:00
abstract:BACKGROUND:A major problem patients encounter when reading about health related issues is document interpretation, which limits reading comprehension and therefore negatively impacts health care. Currently, searching for medical definitions from an external source is time consuming, distracting, and negatively impacts ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-11-4
更新日期:2011-01-25 00:00:00
abstract:BACKGROUND:Evaluation is a challenging but necessary part of the development cycle of clinical information systems like the electronic medical records (EMR) system. It is believed that such evaluations should include multiple perspectives, be comparative and employ both qualitative and quantitative methods. Self-admini...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-4-1
更新日期:2004-02-09 00:00:00
abstract:BACKGROUND:Adopting mobile electronic medical record (MEMR) systems is expected to be one of the superior approaches for improving nurses' bedside and point of care services. However, nurses may use the functions for far fewer tasks than the MEMR supports. This may depend on their technological personality associated t...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-13-88
更新日期:2013-08-12 00:00:00
abstract:BACKGROUND:Electronic medical records (EMRs) contain a variety of valuable medical concepts and relations. The ability to recognize relations between medical concepts described in EMRs enables the automatic processing of clinical texts, resulting in an improved quality of health-related data analysis. Driven by the 201...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-019-0769-0
更新日期:2019-04-09 00:00:00
abstract:BACKGROUND:The objective of this study was to ascertain the performance of syndromic algorithms for the early detection of patients in healthcare facilities who have potentially transmissible infectious diseases, using computerised emergency department (ED) data. METHODS:A retrospective cohort in an 810-bed University...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-13-101
更新日期:2013-09-03 00:00:00
abstract:BACKGROUND:Transient ischemic attack (TIA) is a brief episode of neurological dysfunction resulting from cerebral ischemia not associated with permanent cerebral infarction. TIA is associated with high diagnostic errors because of the subjective nature of findings and the lack of clinical and imaging biomarkers. The go...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-020-01154-6
更新日期:2020-06-18 00:00:00
abstract:BACKGROUND:Mathematical models can be used to predict individual growth responses to growth hormone (GH) therapy. The aim of this study was to construct and validate high-precision models to predict the growth response to GH treatment of short children, independent of their GH status, birth size and gestational age. As...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-7-40
更新日期:2007-12-12 00:00:00
abstract:BACKGROUND:Accumulating evidence has linked environmental exposure, such as ambient air pollution and meteorological factors, to the development and severity of cardiovascular diseases (CVDs), resulting in increased healthcare demand. Effective prediction of demand for healthcare services, particularly those associated...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-020-1101-8
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Emergency room reports pose specific challenges to natural language processing techniques. In this setting, violence episodes on women, elderly and children are often under-reported. Categorizing textual descriptions as containing violence-related injuries (V) vs. non-violence-related injuries (NV) is thus a...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-020-01237-4
更新日期:2020-10-15 00:00:00
abstract:BACKGROUND:Simulation applications on operations management in hospitals are frequently published and claim to support decision-making on operations management subjects. However, the reported implementation rates of recommendations are low and the actual impact of the changes recommended by the modeler has hardly been ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章,评审
doi:10.1186/1472-6947-12-18
更新日期:2012-03-14 00:00:00
abstract:BACKGROUND:With wide applications of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS), statistical comparison of serum peptide profiles and management of patients information play ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-9-13
更新日期:2009-02-17 00:00:00
abstract:BACKGROUND:Diagnostic accuracy might be improved by algorithms that searched patients' clinical notes in the electronic health record (EHR) for signs and symptoms of diseases such as multiple sclerosis (MS). The focus this study was to determine if patients with MS could be identified from their clinical notes prior to...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-017-0418-4
更新日期:2017-02-28 00:00:00
abstract:BACKGROUND:Discharge planning is a care process that aims to secure the transfer of care for the patient at transition from home to the hospital and back home. Information exchange and collaboration between care providers are essential, but deficits are common. A wide range of initiatives to improve the discharge plann...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-016-0285-4
更新日期:2016-04-27 00:00:00
abstract:BACKGROUND:The linkage of records which refer to the same entity in separate data collections is a common requirement in public health and biomedical research. Traditionally, record linkage techniques have required that all the identifying data in which links are sought be revealed to at least one party, often a third ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-4-9
更新日期:2004-06-28 00:00:00
abstract:BACKGROUND:Chronic diseases affect millions of children worldwide leading to substantial disease burden to the children and their families as well as escalating health care costs. The increasing trend in the prevalence of complex pediatric chronic diseases requires innovative and optimal delivery of care. Biomedical in...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章,评审
doi:10.1186/1472-6947-9-22
更新日期:2009-05-05 00:00:00
abstract:BACKGROUND:The necessity to translate eligibility criteria from free text into decision rules that are compatible with data from the electronic health record (EHR) constitutes the main challenge when developing and deploying clinical trial recruitment support systems. Recruitment decisions based on case-based reasoning...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-13-134
更新日期:2013-12-09 00:00:00
abstract:BACKGROUND:Nowadays more and more clinical guidelines for health care professionals are being developed. However, this does not automatically mean that these guidelines are actually implemented. The aim of this meta-review is twofold: firstly, to gain a better understanding of which factors affect the implementation of...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章,meta分析,评审
doi:10.1186/1472-6947-8-38
更新日期:2008-09-12 00:00:00
abstract:BACKGROUND:The Kentucky Cancer Registry (KCR) is a central cancer registry for the state of Kentucky that receives data about incident cancer cases from all healthcare facilities in the state within 6 months of diagnosis. Similar to all other U.S. and Canadian cancer registries, KCR uses a data dictionary provided by t...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-020-01288-7
更新日期:2020-12-15 00:00:00
abstract:BACKGROUND:We have carried out an extensive qualitative research program focused on the barriers and facilitators to successful adoption and use of various features of advanced, state-of-the-art electronic health records (EHRs) within large, academic, teaching facilities with long-standing EHR research and development ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-11-13
更新日期:2011-02-17 00:00:00
abstract:BACKGROUND:The usefulness of syndromic surveillance for early outbreak detection depends in part on effective statistical aberration detection. However, few published studies have compared different detection algorithms on identical data. In the largest simulation study conducted to date, we compared the performance of...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-7-6
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Adjuvant! Online ( http://www.adjuvantonline.com) is an Internet-based software program that allows clinicians to make predictions about the benefits of adjuvant therapy and 10-year survival probability for early-stage breast cancer patients. This model has been validated in Western countries such as the Uni...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-12-108
更新日期:2012-09-17 00:00:00
abstract:BACKGROUND:This study implemented and evaluated a point-of-care, wireless Internet access using smart phones for information retrieval during daily clinical rounds and academic activities of internal medicine residents in a community hospital. We did the project to assess the feasibility of using smart phones as an alt...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-7-5
更新日期:2007-02-21 00:00:00
abstract:BACKGROUND:Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer and the most difficult to predict. When there are no distant metastases, the optimal therapy depends mainly on whether there are malignant lymph nodes in the mediastinum. Given the vigorous debate among specialists about which tests...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-016-0246-y
更新日期:2016-01-26 00:00:00
abstract:BACKGROUND:Automated reporting of estimated glomerular filtration rate (eGFR) is a recent advance in laboratory information technology (IT) that generates a measure of kidney function with chemistry laboratory results to aid early detection of chronic kidney disease (CKD). Because accurate diagnosis of CKD is critical ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-12-69
更新日期:2012-07-12 00:00:00
abstract:BACKGROUND:Congestive heart failure is one of the most common reasons those aged 65 and over are hospitalized in the United States, which has caused a considerable economic burden. The precise prediction of hospitalization caused by congestive heart failure in the near future could prevent possible hospitalization, opt...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-019-0734-y
更新日期:2019-01-31 00:00:00
abstract:BACKGROUND:Since the beginning of 2007, the National Health Research Institutes has been promoting the dissemination of evidence-based medicine (EBM). The current study examined longitudinal trends of behaviors in how hospital-based physicians and nurses have searched for medical information during the spread of EBM. ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-13-4
更新日期:2013-01-07 00:00:00
abstract:BACKGROUND:In the complex domain of medical decision making, reasoning under uncertainty can benefit from supporting tools. Automated decision support tools often build upon mathematical models, such as Bayesian networks. These networks require probabilities which often have to be assessed by experts in the domain of a...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-7-13
更新日期:2007-06-11 00:00:00
abstract:BACKGROUND:New algorithms for disease outbreak detection are being developed to take advantage of full electronic medical records (EMRs) that contain a wealth of patient information. However, due to privacy concerns, even anonymized EMRs cannot be shared among researchers, resulting in great difficulty in comparing the...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-10-59
更新日期:2010-10-14 00:00:00
abstract:BACKGROUND:Virtual Reality has been extensively used in a wide range of psychological experiments. In this study, we aimed to introduce NeuroVirtual 3D, a platform that clinicians could use free of charge. IMPLEMENTATION:The platform we developed relies on NeuroVR software, but we extended it to apply to experiments. ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-016-0276-5
更新日期:2016-03-19 00:00:00