Identification of Hb Q-India (alpha64 Asp-->His) in Thailand.

abstract：:The serum ferritin assays, Ferritin RIA Amersham(TM) and Abbott AxSYM(TM) Ferritin were compared in order to translate values from one assay to the other. Serum ferritin was analysed with both assays in 102 samples. Logarithmic transformation of the results was performed in order to stabilize the variance. The relatio...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Milman N,Byg KE,Juul-Jørgensen B,Weis Bentzon M

更新日期：1999-01-01 00:00:00

abstract：:Chronic granulomatous disease is caused by a genetic defect in the oxidase of phagocytic cells which results in increased susceptibility to recurrent infections. Conventional treatment includes the use of antimicrobials and interpheron-gamma. This study was performed to assess the clinical efficacy of allogeneic bone ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Di Bartolomeo P,Papalinetti G,Olioso P,Di Girolamo G,Bavaro P,De Mattia D,Manzionna MM,Schettini F,Torlontano G

更新日期：1999-01-01 00:00:00

abstract：:Hairy cell leukaemia, previously known as leukaemic reticuloendotheliosis, is an indolent lymphoproliferative disorder of unknown etiology. It typically affects males, causes marked splenomegaly and moderate enlargement of the liver, whilst lymphadenopathy is inconspicuous. Pancytopenia is characteristic with unusuall...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Jacobs P,Wood L,Mansvelt EP,Gartrell K

更新日期：2000-01-01 00:00:00

abstract：:Recently there has been an increased awareness of a possible link between the use of purine nucleoside analogues and myelodysplasia. We report the case of a patient who developed myelodysplasia with complex cytogenetic changes after receiving fludarabine. We review the literature, discuss the possible links between my...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Hennessy BJ,Ryley S,Kasprzyk A,Reid CD

更新日期：2000-01-01 00:00:00

abstract：:Thrombotic microangiopathy is a severe microvascular disorder which may occur in up to 70% of patients undergoing bone marrow transplant. Clinically the term thrombotic microangiopathy encompasses a wide spectrum of syndromes, most importantly the thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Busca A,Uderzo C

更新日期：2000-01-01 00:00:00

abstract：:A forty year old man was seen in 1984 with a four year history of a painful vasculitis that responded transiently to plasma exchange. Diagnosis was revised to atypical pyoderma gangrenosum with further temporary benefit from lamprene and continuing maximally tolerated corticosteroids. The course fluctuated over the ne...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Jacobs P,Wood L,Van Niekerk GD

更新日期：2000-01-01 00:00:00

abstract：:Twenty-five patients with a diagnosis of myelodysplastic syndromes (MDS) were randomized to either begin therapy with pentoxifylline, ciprofloxacin and dexamethasone (PCD) immediately (10 patients) or after a 12 week observation period (control arm, 15 patients). PCD was administered with the goal of suppressing cytok...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Raza A,Qawi H,Andric T,Dar S,Lisak L,Huang RW,Venugopal P,Gezer S,Gregory SA,Hsu WT,Loew J,Robin E,Rifkin S,Shah R,Divgi A,Taylor R,Grosset A

更新日期：2000-01-01 00:00:00

abstract：:A 27-month-old child developed acute hemolysis on two occasions after the administration of cephalosporin. On the first occasion, hemolysis was intravascular and was due to the formation of complexes between antibodies and the drug, which bound to red blood cells and caused severe hemolysis. On the second occasion, he...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Malaponte G,Arcidiacono C,Mazzarino C,Pelligra S,Li Volti G,Bevelacqua V,Li Volti S

更新日期：2000-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study is to assess circulating thrombopoietin concentrations in patients with both clonal and reactive thrombocytosis (RT), which are two distinct categories of extreme platelet production circumstances. Investigation of the thrombopoietin levels in clonal versus reactive thrombocytosis may...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Karakuş S,Ozcebe OI,Haznedaroğlu IC,Göker H,Ozatli D,Koşar A,BüyükaşIk Y,Ertuğrul D,SayInalp N,KirazlI S,Dündar SV

更新日期：2002-02-01 00:00:00

abstract：:Bone marrow stromal cells (MSCs) administered intravenously are effective in reducing neurological deficits after stroke in the rodent. These cells appear to selectively migrate and express neural phenotypes in ischemic brain. To elucidate the mechanisms targeting MSC migration into the ischemic brain, we measured, us...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Wang L,Li Y,Chen X,Chen J,Gautam SC,Xu Y,Chopp M

更新日期：2002-04-01 00:00:00

abstract：:Troxacitabine is a novel L-enantiomer nucleoside analog with unique properties in terms of its structure, pharmacokinetics, intracellular transport, and susceptibility to mechanisms of resistance. Troxacitabine has significant activity in patients with refractory myeloid leukemias, both as a single agent and when comb...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Alvarado Y,Kantarjian HM,Cortes JE,Apostolidou E,Bivins C,Giles FJ

更新日期：2002-06-01 00:00:00

abstract：:The worlds of biology and medicine in general, and the discipline of hematology in particular, enjoy a rich lexicon full of fascinating etymologies. The term "Pawn Ball Megakaryocytes" has been used to describe a peculiar type of abnormal cell that can be found in bone marrow samples taken from some patients with the ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Steensma DP

更新日期：2003-02-01 00:00:00

abstract：UNLABELLED:The product of proto-oncogene c-Myc is a potent activator of cell proliferation. The prognostic importance of the over expression of c-Myc and its transcriptional target Cdc25A in non-Hodgkin lymphoma (NHL) patients remains to be elucidated. To determine the role and the prognostic relevance of c-Myc and Cdc...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Aref S,Fouda M,El-Dosoky E,Menessy A,Mabed M,Saleeb M,Zalata K

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Invasive rhinocerebral mucormycosis is a rare and often fatal opportunistic fungal infection. It is encountered in immunocompromised hosts exemplified by those with diabetes, human immunodeficiency viruses and particularly haematologic malignancies typically after high-dose chemotherapy and stem cell transpl...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Jacobs P,Wood L,Du Toit A,Esterhuizen K

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:This retrospective case-series review studied the effectiveness of epoetin alfa in community oncology practices, which until now has not been well documented. METHODS:We reviewed the medical records of 118 cancer patients treated between 1999 and 2001 with cyclic chemotherapy plus epoetin alfa in 27 US communi...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Harris Spiridonidis C,Brinkmannb K,Fridman M,Gupta S,Tannous RE

更新日期：2003-08-01 00:00:00

abstract：:Non-myeloablative stem cell transplantation (NMT) has been increasingly used in compromised patients who would otherwise have been unable to undergo allotransplant. There is little understanding of the kinetics of immune reconstitution and its influence on infective complications following NMT. The aim of present stud...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Busca A,Lovisone E,Aliberti S,Locatelli F,Serra A,Scaravaglio P,Omedè P,Rossi G,Cirillo D,Barbui A,Ghisetti V,Dall'Omo AM,Falda M

更新日期：2003-10-01 00:00:00

abstract：:The analysis of the T cell receptor (TCR) Vbeta repertoire is one of the most sensitive methods to identify the clonal expansion T cells which respond to tumor associated antigens. Recently, studies have focused on clonally expanded T cells from patients or normal donors induced by leukemia associated antigens in vivo...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Li Y

更新日期：2003-12-01 00:00:00

abstract：:Enhanced neutrophil apoptosis has been reported in neutropenic hepatosplenic schistosomiasis. The shortening of neutrophil survival via apoptosis may explain the neutropenia that occur in these patients. However, the regulation of neutrophil apoptosis in hepatosplenic schistosomiasis has not been clearly defined. Neut...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Aref S,El Refaei MF,Sakrana M,El-Nemre H

更新日期：2004-02-01 00:00:00

abstract：:The thalassaemias are a major health problem, and approximately 1 in 14 of the population are carriers for one of the sub types. For the purpose of prevention and control of clinically severe disease, molecular diagnosis either pre-natally or ante natal with genetic counselling are increasingly important. The majority...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Gu X,Zeng Y

更新日期：2002-08-01 00:00:00

abstract：:Disseminated intravascular coagulation (DIC) is characterized by an acute generalized, widespread activation of coagulation, which results in thrombotic complications, due to the intravascular formation of fibrin, as well as diffuse hemorrhages, due to the consumption of platelets and coagulation factors. In this revi...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Franchini M,Manzato F

更新日期：2004-04-01 00:00:00

abstract：:Granulocyte-macrophage colony stimulating factor (GM-CSF) enhances immune responses by inducing the proliferation, maturation, and migration of dendritic cells, and the expansion and differentiation of B and T lymphocytes. There is significant data in pre-clinical animal models demonstrating the adjuvant effects of GM...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Chang DZ,Lomazow W,Joy Somberg C,Stan R,Perales MA

更新日期：2004-06-01 00:00:00

abstract：:Acquired hemophilia is a rare disorder with an estimated annual incidence of 0.2-1 cases per million individuals. The etiology of the disorder remains obscure, although approximately half of all cases are associated with other underlying conditions. In acquired hemophilia, the severe hemorrhagic diathesis is caused by...

journal_title：Hematology (Amsterdam, Netherlands)

authors： von Depka M

更新日期：2004-08-01 00:00:00

abstract：:Prior to European settlement indigenous Australians were hunter-gatherers who lived in geographically isolated small clan groups, also separated by elaborate totemic rules. Today they still reside in isolated communities throughout Australia but many have moved to the cities. They share a high incidence of a range of ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Erber WN,Buck AM,Threlfall TJ

更新日期：2004-10-01 00:00:00

abstract：:Alemtuzumab (Campath 1H -MabCampath), initially used for prophylaxis of graft versus host disease in allogenic transplantaion, is now increasingly used for refractory chronic lymphatic leukaemia (CLL). Its efficacy has been well documented in this--the commonest form of leukaemia. Alemtuzumab is associated with severe...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Haider I,Cahill M

更新日期：2004-10-01 00:00:00

abstract：:The primary cause of treatment failures in acute myeloid leukemia (AML) is the emergence of both resistant disease and early relapse. Among the most frequent agents of these phenomena are defects in the mitochondrial-mediated apoptotic pathway. This pathway is regulated by bcl-2 family of anti-apoptotic (bcl-2, bcl-xl...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Del Principe MI,Del Poeta G,Venditti A,Buccisano F,Maurillo L,Mazzone C,Bruno A,Neri B,Irno Consalvo M,Lo Coco F,Amadori S

更新日期：2005-02-01 00:00:00

abstract：:Hematologists have classically been the treating physicians of patients with Gaucher disease, and today, despite both specific and symptomatic therapeutic advances, they remain at the forefront of specialists to whom patients with Gaucher disease present. It is therefore appropriate to review that has changed and what...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Zimran A,Altarescu G,Rudensky B,Abrahamov A,Elstein D

更新日期：2005-04-01 00:00:00

abstract：:Neoplasms putatively originating from precursor and mature natural killer (NK) cells are rare, and their clinical features are unclear. A nationwide survey was performed in Japan to clarify the clinical features of these neoplasms diagnosed between 1994 and 1998, and data for 237 patients who met the criteria for puta...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Oshimi K,Kawa K,Nakamura S,Suzuki R,Suzumiya J,Yamaguchi M,Kameoka J,Tagawa S,Imamura N,Ohshima K,Kojya S,Iwatsuki K,Tokura Y,Sato E,Sugimori H,NK-cell Tumor Study Group.

更新日期：2005-06-01 00:00:00

abstract：:Thymic function is important for the generation of T-cell diversity in the periphery of both children and adults during both health and disease. Until recently, thymic function could not be monitored, as a consequence of the absence of adequate technology to differentiate recent thymic emigrants (RTEs) from naïve T ce...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Li Y

更新日期：2005-08-01 00:00:00

abstract：:The molecular basis for aggressive transformation of multiple myeloma (MM) and other cancers is not completely understood. Global gene expression profiling on highly purified malignant plasma cells from 351 newly diagnosed patients with MM treated with autologous stem cell transplantation revealed a statistically sign...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Shaughnessy J

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:We report the first case of EBV-PTLD and pure red cell aplasia (PRCA) after an unrelated cord blood transplant in China, who was successfully treated with Rituximab. METHODS:Case report and literature review. RESULTS:A 5-year-old girl with CML underwent a major ABO-incompatible HLA-identical unrelated cord ...

journal_title：Hematology (Amsterdam, Netherlands)

authors： Zhu K,Chen J,Chen S

更新日期：2005-10-01 00:00:00