Mink is a highly susceptible host species to circulating human and avian influenza viruses.

abstract：:Hepatitis B infection, especially by perinatal transmission, is endemic in Asian countries. After the first successful universal hepatitis B virus (HBV) vaccination programme for newborns in Taiwan, it became feasible to prevent HBV transmission and the resultant hepatocellular carcinoma in endemic countries. However,...

journal_title：Emerging microbes & infections

authors： Su TH,Chen PJ

更新日期：2012-09-01 00:00:00

abstract：:The incidence and severity of hand, foot and mouth disease have increased in mainland China since 2008. Therapies and vaccines are currently at different stages of development. This study aimed to determine the social factors associated with the outbreaks and severity of the disease in Chinese children. A multicentre,...

journal_title：Emerging microbes & infections

authors： Zeng M,Pu D,Mo X,Zhu C,Gong S,Xu Y,Lin G,Wu B,He S,Jiao X,Wang X,Wang X,Zhu Q,Altmeyer R

更新日期：2013-10-01 00:00:00

abstract：:We sought to review the epidemiology, international geographical distribution, and economic consequences of selected swine zoonoses. We performed literature searches in two stages. First, we identified the zoonotic pathogens associated with swine. Second, we identified specific swine-associated zoonotic pathogen repor...

journal_title：Emerging microbes & infections

authors： Uddin Khan S,Atanasova KR,Krueger WS,Ramirez A,Gray GC

更新日期：2013-12-01 00:00:00

abstract：:While much is known about the prevalence of influenza viruses in North America and Eurasia, their prevalence in birds and mammals in South America is largely unknown. To fill this knowledge gap and provide a baseline for future ecology and epidemiology studies, we conducted 2 years of influenza surveillance in the eas...

journal_title：Emerging microbes & infections

authors： Karlsson EA,Ciuoderis K,Freiden PJ,Seufzer B,Jones JC,Johnson J,Parra R,Gongora A,Cardenas D,Barajas D,Osorio JE,Schultz-Cherry S

更新日期：2013-04-01 00:00:00

abstract：:Pyrazinamide (PZA) is a frontline anti-tuberculosis drug that plays a crucial role in the treatment of both drug susceptible and multidrug-resistant tuberculosis (MDR-TB). Resistance to PZA is most commonly associated with mutations in the pncA gene encoding nicotinamidase/pyrazinamidase which converts the prodrug PZA...

journal_title：Emerging microbes & infections

authors： Zhang S,Chen J,Shi W,Liu W,Zhang W,Zhang Y

更新日期：2013-06-01 00:00:00

abstract：:Clostridium difficile is a spore-forming gram-positive bacillus, and the leading cause of antibiotic-associated nosocomial diarrhea and colitis in the industrialized world. With the emergence of a hypervirulent strain of C. difficile (BI/NAP1/027), the epidemiology of C. difficile infection has rapidly changed in the ...

journal_title：Emerging microbes & infections

authors： Ghose C

更新日期：2013-09-01 00:00:00

abstract：:Neuraminidase inhibitors (NAIs) are the only available licensed therapeutics against human H7N9 influenza virus infections. The emergence of NAI-resistant variants of H7N9viruses with an NA R292K mutation poses a therapeutic challenge. A comprehensive understanding of the susceptibility of these viruses to clinically ...

journal_title：Emerging microbes & infections

authors： Zhang X,Song Z,He J,Yen HL,Li J,Zhu Z,Tian D,Wang W,Xu L,Guan W,Liu Y,Wang S,Shi B,Zhang W,Qin B,Cai J,Wan Y,Xu C,Ren X,Chen H,Liu L,Yang Y,Zhou X,Zhou W,Xu J,Zhang X,Peiris M,Hu Y,Yuan Z

更新日期：2014-11-01 00:00:00

abstract：:A wide range of influenza A viruses of pigs and birds have infected humans in the last decade, sometimes with severe clinical consequences. Each of these so-called zoonotic infections provides an opportunity for virus adaptation to the new host. Fortunately, most of these human infections do not yield viruses with the...

journal_title：Emerging microbes & infections

authors： Schrauwen EJ,Fouchier RA

更新日期：2014-02-01 00:00:00

abstract：:Vaccine development and pathogenesis studies for human enterovirus 71 are limited by a lack of suitable animal models. Here, we report the development of a novel neonatal gnotobiotic pig model using the non-pig-adapted neurovirulent human enterovirus 71 strain BJ110, which has a C4 genotype. Porcine small intestinal e...

journal_title：Emerging microbes & infections

authors： Yang X,Li G,Wen K,Bui T,Liu F,Kocher J,Jortner BS,Vonck M,Pelzer K,Deng J,Zhu R,Li Y,Qian Y,Yuan L

更新日期：2014-05-01 00:00:00

abstract：:Predominantly occurring in developing parts of the world, Buruli ulcer is a severely disabling mycobacterium infection which often leads to extensive necrosis of the skin. While the exact route of transmission remains uncertain, like many tropical diseases, associations with climate have been previously observed and c...

journal_title：Emerging microbes & infections

authors： Morris A,Gozlan RE,Hassani H,Andreou D,Couppié P,Guégan JF

更新日期：2014-08-01 00:00:00

abstract：:Fluoroquinolone resistance is gradually acquired through several mechanisms. In particular, chromosomal mutations in the genes encoding topoisomerases II and IV and increased expression of the multidrug efflux pump AcrAB-TolC are the most common mechanisms. In this study, multiplex polymerase chain reaction (PCR) prot...

journal_title：Emerging microbes & infections

authors： Zayed AA,Essam TM,Hashem AG,El-Tayeb OM

更新日期：2015-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1038/emi.2015.1.]. ...

journal_title：Emerging microbes & infections

authors： Liu H,Zhao Y,Zhao D,Gong T,Wu Y,Han H,Xu T,Peschel A,Han S,Qu D

更新日期：2015-03-01 00:00:00

abstract：:The complement system, an important part of innate immunity, plays a critical role in pathogen clearance. Unregulated complement activation is likely to play a crucial role in the pathogenesis of acute lung injury (ALI) induced by highly pathogenic virus including influenza A viruses H5N1, H7N9, and severe acute respi...

journal_title：Emerging microbes & infections

authors： Wang R,Xiao H,Guo R,Li Y,Shen B

更新日期：2015-05-01 00:00:00

abstract：:The fourth conserved region (C4) in the HIV-1 envelope glycoprotein (Env) gp120 is a structural element that is important for its function, as it binds to both the receptor CD4 and the co-receptor CCR5/CXCR4. It has long been known that this region is highly immunogenic and that it harbors B-cell as well as T-cell epi...

journal_title：Emerging microbes & infections

authors： Pan R,Chen Y,Vaine M,Hu G,Wang S,Lu S,Kong XP

更新日期：2015-07-01 00:00:00

abstract：:Capnocytophaga canimorsus are gram-negative bacteria living as commensals in the mouth of dogs and cats. C. canimorsus cause rare but life-threatening generalized infections in humans that have been in contact with a dog or a cat. Over the last years we collected 105 C. canimorsus strains from different geographical o...

journal_title：Emerging microbes & infections

authors： Renzi F,Dol M,Raymackers A,Manfredi P,Cornelis GR

更新日期：2015-08-01 00:00:00

abstract：:A universal rotavirus (RV) immunization program is a potentially cost-effective measure for preventing RV infection in China. However, the efficacy of the only licensed RV vaccine (Lanzhou lamb rotavirus vaccine, LLR), which is made by a domestic manufacturer, has not been proven by a properly designed clinical trial....

journal_title：Emerging microbes & infections

authors： Zhen SS,Li Y,Wang SM,Zhang XJ,Hao ZY,Chen Y,Wang D,Zhang YH,Zhang ZY,Ma JC,Zhou P,Zhang Z,Jiang ZW,Zhao YL,Wang XY

更新日期：2015-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection affects approximately 3% of the world's population and causes chronic liver diseases, including liver fibrosis, cirrhosis, and hepatocellular carcinoma. Although current antiviral therapy comprising direct-acting antivirals (DAAs) can achieve a quite satisfying sustained virological r...

journal_title：Emerging microbes & infections

authors： Qian XJ,Zhu YZ,Zhao P,Qi ZT

更新日期：2016-01-06 00:00:00

abstract：:Lyme disease is the leading tick-borne disease in the USA. Whereas the majority of Lyme disease patients with early disease can be cured with standard treatment, some patients suffer from chronic fatigue and joint and muscular pain despite treatment, a syndrome called posttreatment Lyme disease syndrome. Although the ...

journal_title：Emerging microbes & infections

authors： Feng J,Shi W,Zhang S,Zhang Y

更新日期：2015-06-03 00:00:00

abstract：:Aluminum compounds (alum) are the most widely used adjuvants in veterinary and human vaccines. Alum was initially thought to be a simple depot for antigen retention; however, our understanding of the mechanism by which it works has progressed substantially in recent decades. Nonetheless, consensus regarding its roles ...

journal_title：Emerging microbes & infections

authors： Wen Y,Shi Y

更新日期：2016-03-23 00:00:00

abstract：:The purpose of this study was to identify fecal bacterial microbiome changes in patients with chronic human immunodeficiency virus (HIV) infection in China. Bacterial 16S rRNA genes were amplified, sequenced (454 pyrosequencing), and clustered into operational taxonomic units using the QIIME software. Relative abundan...

journal_title：Emerging microbes & infections

authors： Sun Y,Ma Y,Lin P,Tang YW,Yang L,Shen Y,Zhang R,Liu L,Cheng J,Shao J,Qi T,Tang Y,Cai R,Guan L,Luo B,Sun M,Li B,Pei Z,Lu H

更新日期：2016-04-06 00:00:00

abstract：:Pteropine orthoreovirus (PRV), potentially of bat origin, is reported to be a causative agent of emerging respiratory tract infections among humans in Southeast Asia. We evaluated the efficacy of serologic assays using the major outer capsid and cell attachment proteins (CAP) of PRV strains in the screening, confirmat...

journal_title：Emerging microbes & infections

authors： Singh H,Shimojima M,Fukushi S,Fukuma A,Tani H,Yoshikawa T,Taniguchi S,Yang M,Sugamata M,Morikawa S,Saijo M

更新日期：2016-05-11 00:00:00

abstract：:Cryptococcal meningitis is an important fungal infection among systemic lupus erythematosus patients. We conducted a pooled analysis and systematic review to describe the epidemiological and clinical profile of cryptococcal meningitis in systemic lupus erythematosus patients. From two hospitals in China and nine liter...

journal_title：Emerging microbes & infections

authors： Fang W,Chen M,Liu J,Hagen F,Ms A,Al-Hatmi,Zhang P,Guo Y,Boekhout T,Deng D,Xu J,Pan W,Liao W

更新日期：2016-09-07 00:00:00

abstract：:Human enterovirus 71 (EV-A71) causes hand, foot and mouth disease (HFMD). EV-A71 circulates in many countries and has caused large epidemics, especially in the Asia-Pacific region, since 1997. In April 2012, an undiagnosed fatal disease with neurological involvement and respiratory distress occurred in young children ...

journal_title：Emerging microbes & infections

authors： Duong V,Mey C,Eloit M,Zhu H,Danet L,Huang Z,Zou G,Tarantola A,Cheval J,Perot P,Laurent D,Richner B,Ky S,Heng S,Touch S,Sovann L,van Doorn R,Tan Tran T,Farrar JJ,Wentworth DE,Das SR,Stockwell TB,Manuguerra JC,

更新日期：2016-09-21 00:00:00

abstract：:The Saffold virus (SAFV) genome is translated as a single long polyprotein precursor and co-translationally cleaved to yield 12 separate viral proteins. Little is known about the activities of SAFV proteins although their homologs in other picornaviruses have already been described. To further support research on func...

journal_title：Emerging microbes & infections

authors： Xu Y,Victorio CB,Ng Q,Prabakaran M,Tan YJ,Chua KB

更新日期：2016-10-12 00:00:00

abstract：:Current antimicrobial susceptibility testing has limited screening capability for identifying empirical antibiotic combinations to treat severe bacterial infections with multidrug-resistant (MDR) organisms. We developed a new antimicrobial susceptibility assay using automated ultra-high-throughput screen technology in...

journal_title：Emerging microbes & infections

authors： Sun W,Weingarten RA,Xu M,Southall N,Dai S,Shinn P,Sanderson PE,Williamson PR,Frank KM,Zheng W

更新日期：2016-11-09 00:00:00

abstract：:Escherichia coli is both of a widespread harmless gut commensal and a versatile pathogen of humans. Domestic animals are a well-known reservoir for pathogenic E. coli. However, studies of E. coli populations from wild animals that have been separated from human activities had been very limited. Here we obtained 580 is...

journal_title：Emerging microbes & infections

authors： Lu S,Jin D,Wu S,Yang J,Lan R,Bai X,Liu S,Meng Q,Yuan X,Zhou J,Pu J,Chen Q,Dai H,Hu Y,Xiong Y,Ye C,Xu J

更新日期：2016-12-07 00:00:00

abstract：:Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe human infections and dromedary camels are considered an intermediary host. The dynamics of natural infection in camels are not well understood. Through systematic surveillance in Egypt, nasal, rectal, milk, urine and serum samples were collected fro...

journal_title：Emerging microbes & infections

authors： Ali MA,Shehata MM,Gomaa MR,Kandeil A,El-Shesheny R,Kayed AS,El-Taweel AN,Atea M,Hassan N,Bagato O,Moatasim Y,Mahmoud SH,Kutkat O,Maatouq AM,Osman A,McKenzie PP,Webby RJ,Kayali G

更新日期：2017-01-04 00:00:00

abstract：:We report the first imported case of Rift Valley fever (RVF) in China. The patient returned from Angola, a non-epidemic country, with an infection of a new reassortant from different lineages of Rift Valley fever viruses (RVFVs). The patient developed multiorgan dysfunction and gradually recovered with continuous rena...

journal_title：Emerging microbes & infections

authors： Liu J,Sun Y,Shi W,Tan S,Pan Y,Cui S,Zhang Q,Dou X,Lv Y,Li X,Li X,Chen L,Quan C,Wang Q,Zhao Y,Lv Q,Hua W,Zeng H,Chen Z,Xiong H,Jiang C,Pang X,Zhang F,Liang M,Wu G,Gao GF,Liu WJ,Li A,Wang Q

更新日期：2017-01-18 00:00:00

abstract：:Zika virus (ZIKV) is an emerging RNA virus in the widespread Flavivirus genus. Recently, ZIKV has rapidly spread around the world and has been implicated in human disease, including neurological disorders, triggering public and scientific attention. Understanding how ZIKV causes disease is the highest priority, yet li...

journal_title：Emerging microbes & infections

authors： Wang A,Thurmond S,Islas L,Hui K,Hai R

更新日期：2017-03-22 00:00:00

abstract：:Subtype H6 influenza A viruses (IAVs) are commonly detected in wild birds and domestic poultry and can infect humans. In 2010, a H6N6 virus emerged in southern China, and since then, it has caused sporadic infections among swine. We show that this virus binds to α2,6-linked and α2,3-linked sialic acids. Mutations at r...

journal_title：Emerging microbes & infections

authors： Sun H,Kaplan BS,Guan M,Zhang G,Ye J,Long LP,Blackmon S,Yang CK,Chiang MJ,Xie H,Zhao N,Cooley J,Smith DF,Liao M,Cardona C,Li L,Wang GP,Webby R,Wan XF

更新日期：2017-04-12 00:00:00