Abstract：
:The Coronavirus disease in 2019 (COVID-19), also referred to as the novel 'CoV19 (nCov19)' is caused by a new coronavirus strain similar to Severe Acute Respiratory Syndrome (SARS-CoV-2). SARS-CoV-2 spreads via respiratory droplets, saliva, or direct contact. Therefore it is important to control the viral load in the saliva and respiratory secretions. One of the most simple and cost-effective measures that can be adopted by the public and healthcare professionals to prevent cross-contamination and community transmission, is the implementation of effective oral and throat hygiene. Recent evidence has confirmed that 0.5% povidone iodine (PVP-I) mouthrinse/gargle for 30 s can reduce SARS-CoV-2 virus infectivity to below detectable levels. PVP-I can even interrupt SARS-CoV-2 attachment to oral and nasopharyngeal tissues and lower the viral particles in the saliva and respiratory droplets. Thus, the use of PVP-I mouthrinse as a prophylactic measure has been advocated across the globe to reduce disease transmission. Although the efficacy of PVP-I against SARS-CoV-2 is proven, no review articles have yet discussed the evidence and mechanisms of PVP-I against the SARS-CoV-2. Thus, this paper highlights the rationale, safety, recommendations, and dosage of PVP-I gargle/mouthrinse as an effective method to decrease the viral loads during the pressing times of COVID-19.
journal_name
Jpn Dent Sci Revjournal_title
The Japanese dental science reviewauthors
Chopra A,Sivaraman K,Radhakrishnan R,Balakrishnan D,Narayana Adoi
10.1016/j.jdsr.2021.03.001keywords:
["COVID-19","Coronavirus","Global health","Mouthwash","Oral health","Povidone-iodine","SARS-CoV-2","Viral infection"]subject
Has Abstractpub_date
2021-11-01 00:00:00pages
39-45eissn
1882-7616issn
2213-6851pii
S1882-7616(21)00006-5journal_volume
57pub_type
杂志文章,评审相关文献
文献大全abstract：:Aggressive periodontitis (AgP) is a form of periodontitis that affects adolescents and has a significantly higher prevalence in individuals of African descent. AgP typically shows familial aggregation, suggesting a genetic predisposition. Young age, good health status, rapid attachment loss, and familial aggregation a...
journal_title：The Japanese dental science review
pub_type： 杂志文章,评审
doi：10.1016/j.jdsr.2020.12.001
更新日期：2021-11-01 00:00:00
abstract：:Chewing is one of the most important orofacial functions. During this process, food is reduced in size, while saliva moistens the food and binds it into a bolus that can be easily swallowed. Characteristics of the oral system, including the number of teeth, bite force, and salivary flow, influence the masticatory proc...
journal_title：The Japanese dental science review
pub_type： 杂志文章,评审
doi：10.1016/j.jdsr.2019.11.001
更新日期：2020-12-01 00:00:00
abstract：:The purpose of this review was to present the currently available information on oral appliance (OA) therapy for dentists, especially clinic-based dentists, to aid them in performing this treatment for the management of symptoms of obstructive sleep apnea (OSA). The clinical research evidence comprised of systematic r...
journal_title：The Japanese dental science review
pub_type： 杂志文章,评审
doi：10.1016/j.jdsr.2019.10.002
更新日期：2020-12-01 00:00:00
abstract：:Inflammation substantially affects the risk of oral malignancy. Pro-inflammatory cytokine, interferon (IFN)-γ, confers anti-tumor activity using several different mechanisms. Conversely, higher expression of interleukin (IL)-17 is associated with worse prognosis. Monocyte chemotactic protein (MCP)-1 correlates positiv...
journal_title：The Japanese dental science review
pub_type： 杂志文章,评审
doi：10.1016/j.jdsr.2019.09.001
更新日期：2019-11-01 00:00:00
abstract：Purpose:To compare marginal bone level changes (MBLCs) of immediately- and conventionally-loaded implants supporting a mandibular implant overdenture (IOD). Materials and methods:Both electronic (MEDLINE, PubMed, and The Cochrane Library) and manual searches were conducted for all relevant studies published from 1 Jan...
journal_title：The Japanese dental science review
pub_type： 杂志文章,评审
doi：10.1016/j.jdsr.2018.09.005
更新日期：2019-11-01 00:00:00
abstract：:The oral and maxillofacial region has a complicated anatomy with critical contiguous organs, including the brain, eyes, vital teeth, and complex networks of nerves and blood vessels. Therefore, advances in basic scientific research within the field of intraoperative oral and maxillofacial surgery have enabled the intr...
journal_title：The Japanese dental science review
pub_type： 杂志文章,评审
doi：10.1016/j.jdsr.2018.03.005
更新日期：2018-08-01 00:00:00
abstract：:The causes of pain symptoms in the temporomandibular joint (TMJ) and masticatory muscle (MM) regions may not be determined by clinical examination alone. In this review, we document that pain symptoms of the TMJ and MM regions in patients with temporomandibular disorders (TMDs) are associated with computed tomography ...
journal_title：The Japanese dental science review
pub_type： 杂志文章,评审
doi：10.1016/j.jdsr.2016.04.004
更新日期：2016-11-01 00:00:00
abstract：:Nitric oxide (NO) is a free radical which is produced from a wide variety of cells and tissues in the human body. NO is involved in the regulation of many physiological processes, such as vascular relaxation, neurotransmission, immune regulation, and cell death. NO is generated by nitric oxide synthase (NOS), which ha...
journal_title：The Japanese dental science review
pub_type： 杂志文章,评审
doi：10.1016/j.jdsr.2015.08.001
更新日期：2016-02-01 00:00:00
abstract：:Dry mouth results from hypofunction of the salivary glands due to Sjögren's syndrome (SS), various medications, and radiation therapy for head and neck cancer. In severe cases of salivary gland hypofunction, sialagogues are not always effective due to the loss of salivary parenchyma. Therefore, regenerative medicine u...
journal_title：The Japanese dental science review
pub_type： 杂志文章,评审
doi：10.1016/j.jdsr.2021.03.002
更新日期：2021-11-01 00:00:00
abstract：:Molar incisor hypomineralization (MIH) is defined as hypomineralization of systemic origin of one to four first permanent molars, and incisors are also frequently affected. This disorder is a serious concern in pediatric dentistry. Teeth affected by MIH have many dental problems, such as hypersensitivity, poor aesthet...
journal_title：The Japanese dental science review
pub_type： 杂志文章,评审
doi：10.1016/j.jdsr.2021.05.001
更新日期：2021-11-01 00:00:00
abstract：:This article presents a review of silver-based dental alloys, with a focus on their bonding behavior and their chemical and mechanical properties. The most effective pretreatment for bonding silver-based alloys involves alumina air-abrasion followed by the application of a metal adhesive primer containing both the vin...
journal_title：The Japanese dental science review
pub_type： 杂志文章,评审
doi：10.1016/j.jdsr.2021.05.005
更新日期：2021-11-01 00:00:00
