Abstract：
:Selenium levels in the Inuit population of Greenland have been declining during the last decades. The association between Selenium and asthma has been investigated previously, but with conflicting results. The objective was to measure human serum Se (s-Se) in Greenlandic seafood processing workers, to compare with levels recorded in previous decades and to establish if s-Se is associated with asthma or lung function. Data, including questionnaire answers, spirometry, skin-prick test and s-Se from 324 seafood processing workers in Greenland were collected during 2016-2017. Mean s-Se values were compared by t-test and one-way ANOVA. Associations between s-Se and asthma, symptoms from the lower airways at work and lung function were assessed using linear regression. The mean s-Se was 96.2 µg/L. S-Se was higher among non-smokers and workers living in settlements. Workers with asthma did not have s-Se levels significantly different from those of non-asthmatics. We found a positive association between s-Se levels and FEV1 values. Selenium levels appear to continue declining in Greenland, presumably because of a more Westernised lifestyle. The health effects of declining Selenium levels remain unclear. We did not establish an association between s-Se and asthma, but we did record a positive association between s-Se and FEV1.
journal_name
Int J Circumpolar Healthjournal_title
International journal of circumpolar healthauthors
Laustsen BH,Omland Ø,Würtz ET,Jørgensen L,Bønløkke JHdoi
10.1080/22423982.2021.1972525keywords:
["Greenland","Selenium","antioxidant","asthma","inuit","lung function","seafood"]subject
Has Abstractpub_date
2021-12-01 00:00:00pages
1972525issue
1eissn
1239-9736issn
2242-3982journal_volume
80pub_type
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