The effect of unilateral partial facial paralysis on nasofrontal sutural growth: an experimental study in the rabbit.

Abstract:

:In a previous study in the rabbit, it was demonstrated that paralysis of the midfacial musculature results in decreased anteroposterior growth of the snout. At the end of growth, these animals showed macroscopically striking similarities to animals with unilateral fusion of the nasofrontal suture. In this study, whether nasofrontal sutural growth is unilaterally restricted in animals with unilateral partial facial paralysis was investigated. A left-sided partial facial paralysis was induced in sixteen 12-day-old New Zealand White rabbits. At the ages of 5, 9, 12, and 17 weeks, four animals were randomly assigned to be killed for analysis of nasofrontal sutural growth. In each animal, the left experimental side was compared with the right control side. By means of histomorphometric measurements, it was shown that diminished sutural growth activity was present on the left paralyzed side in periods of rapid growth. On the other hand, no significant alterations in sutural width were found. These findings seem to explain some of the macroscopic growth alterations (i.e., diminished anterior maxillary length) observed in rabbits with unilateral partial facial paralysis.

journal_name

Plast Reconstr Surg

authors

Sinsel NK,Guelinckx PJ,Opdebeeck H

doi

10.1097/00006534-199906000-00013

subject

Has Abstract

pub_date

1999-06-01 00:00:00

pages

1887-92

issue

7

eissn

0032-1052

issn

1529-4242

journal_volume

103

pub_type

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