Confirmation of the pulse oximetry gap in carbon monoxide poisoning.

Abstract:

STUDY OBJECTIVES:To demonstrate the degree to which pulse oximetry overestimates actual oxyhemoglobin (O2Hb) saturation in patients with carbon monoxide (CO) poisoning. This phenomenon has been reported in fewer than 20 humans in the English medical literature. METHODS:A retrospective chart review of 191 patients evaluated for CO poisoning at a regional hyperbaric center identified 124 patients 10 years of age and older who had had both arterial blood gas and pulse oximetry measurements and who had received either high-flow oxygen through a nonrebreather mask or 100% inspired oxygen through an endotracheal tube. Blood gas measurements, including direct spectrophotometric determination of O2Hb and carboxyhemoglobin (COHb) saturation values, were compared with finger-probe pulse oximetry readings. RESULTS:Measured O2Hb saturation (mean +/- SD, 88.7 +/- 10.2%; range, 51.4% to 99.0%) decreased linearly and predictably with rising COHb levels (10.7 +/- 10.4%; range, .2% to 46.4%). Pulse oximetry saturation (99.2% +/- 1.3%; range, 92% to 100%) remained elevated across the range of COHb levels and failed to detect decreased O2Hb saturation. The pulse oximetry gap, defined as the difference between pulse oximetry saturation and actual O2Hb saturation (10.5% +/- 9.7%; range, 0% to 40.6%), approximated the COHb level. CONCLUSION:There is a linear decline in O2Hb saturation as COHb saturation increases. This decline is not detected by pulse oximetry, which therefore overestimates O2Hb saturation in patients with increased COHb levels. The pulse oximetry gap increases with higher levels of COHb and approximates the COHb level. In patients with possible CO poisoning, pulse oximetry must be considered unreliable and interpreted with caution until the COHb level has been measured.

journal_name

Ann Emerg Med

authors

Bozeman WP,Myers RA,Barish RA

doi

10.1016/s0196-0644(97)70077-5

subject

Has Abstract

pub_date

1997-11-01 00:00:00

pages

608-11

issue

5

eissn

0196-0644

issn

1097-6760

pii

S0196-0644(97)70077-5

journal_volume

30

pub_type

杂志文章
  • Profile of patients with human immunodeficiency virus infection presenting to an inner-city emergency department: preliminary report.

    abstract::Increasing numbers of patients with diagnosed HIV infection are presenting to inner-city emergency departments. Unfortunately, there is little information available on the characteristics and emergency clinical problems of HIV-infected patients to guide physicians in patient care and strategies for resource use. Preli...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(05)82555-7

    authors: Kelen GD,Johnson G,DiGiovanna TA,Loring K,Sivertson KT

    更新日期:1990-09-01 00:00:00

  • Usefulness and validity of diagnostic nasogastric aspiration in patients without hematemesis.

    abstract:STUDY OBJECTIVE:We estimate the test characteristics of nasogastric aspiration to diagnose upper gastrointestinal tract hemorrhage in patients without hematemesis. METHODS:In this retrospective cohort study, medical records from patients admitted to 2 urban hospitals between 1997 and 2002 for gastrointestinal tract bl...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2003.09.002

    authors: Witting MD,Magder L,Heins AE,Mattu A,Granja CA,Baumgarten M

    更新日期:2004-04-01 00:00:00

  • Overwhelming postsplenectomy infection.

    abstract::A characteristic case of overwhelming postsplenectomy infection in a previously healthy, 25-year-old man is presented. The patient progressed from influenza-like symptoms to irreversible septic shock and death within 24 hours. His spleen had been removed nine years earlier because of abdominal trauma. Aggressive thera...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0196-0644(88)80304-4

    authors: Stryker RM,Orton DW

    更新日期:1988-02-01 00:00:00

  • Lacerations and Embedded Needles Caused by Epinephrine Autoinjector Use in Children.

    abstract:STUDY OBJECTIVE:Epinephrine autoinjector use for anaphylaxis is increasing. There are reports of digit injections because of incorrect autoinjector use, but no previous reports of lacerations, to our knowledge. We report complications of epinephrine autoinjector use in children and discuss features of these devices, an...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2015.07.011

    authors: Brown JC,Tuuri RE,Akhter S,Guerra LD,Goodman IS,Myers SR,Nozicka C,Manzi S,Long K,Turner T,Conners GP,Thompson RW,Park E

    更新日期:2016-03-01 00:00:00

  • Frequent users of emergency departments: developing standard definitions and defining prominent risk factors.

    abstract:STUDY OBJECTIVE:We identify factors that define frequent and highly frequent emergency department (ED) users. METHODS:Administrative health care records were used to define less frequent (1 to 6 visits), frequent (7 to 17 visits), and highly frequent (≥18 visits) ED users. Analyses were conducted to determine the most...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2011.11.036

    authors: Doupe MB,Palatnick W,Day S,Chateau D,Soodeen RA,Burchill C,Derksen S

    更新日期:2012-07-01 00:00:00

  • Association of Antibiotic Choice With Hospital Length of Stay and Risk Factors for Readmission in Patients With Sickle Cell Disease and Acute Chest Syndrome: An Observational Cohort Study.

    abstract:STUDY OBJECTIVE:We determine the association between use of specific cephalosporins and macrolides and hospital length of stay in patients with sickle cell disease (SCD) who are admitted with acute chest syndrome, and determine treatment risk factors for acute chest syndrome-related 30-day readmission. METHODS:Patient...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2020.08.011

    authors: Badaki-Makun O,Casella JF,Tackett S,Tao X,Chamberlain JM

    更新日期:2020-09-01 00:00:00

  • Application of the trauma score in the prehospital setting.

    abstract::The Trauma Score (TS) is a physiologic measure of injury severity that correlates with patient outcome. Application of the TS has shown that it is useful for patient triage, for predicting patient outcome, and as a means of normalizing for case mix when comparing prehospital care and transport modalities. Our study ex...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(85)80917-3

    authors: Moreau M,Gainer PS,Champion H,Sacco WJ

    更新日期:1985-11-01 00:00:00

  • Geriatric training in emergency medicine residency programs.

    abstract:STUDY OBJECTIVES:The health care needs of the elderly population are significantly different from those of younger patients and require special knowledge and skills on the part of emergency physicians. The purpose of this study was to identify the nature and extent of geriatric training currently provided to emergency ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(05)81029-7

    authors: Jones JS,Rousseau EW,Schropp MA,Sanders AB

    更新日期:1992-07-01 00:00:00

  • Future role of thrombolytic therapy in emergency medicine.

    abstract::Thrombolytic therapy offers the promise of major therapeutic intervention in many areas as well as in the treatment of patients with acute myocardial infarction who present to the emergency department. Infusion of tissue-type plasminogen activator (tPA) during field transport has been proven safe, but optimal methods ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0196-0644(89)80271-9

    authors: Bresler MJ

    更新日期:1989-12-01 00:00:00

  • Preliminary program evaluation of emergency department HIV prevention counseling.

    abstract:OBJECTIVE:Controversy surrounds the linkage of prevention counseling with emergency department (ED)-based HIV testing. Further, the effectiveness and feasibility of prevention counseling in the ED setting is unknown. We investigate these issues by conducting a preliminarily exploration of several related aspects of our...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2011.03.036

    authors: Sitlinger AP,Lindsell CJ,Ruffner AH,Wayne DB,Hart KW,Trott AT,Fichtenbaum CJ,Lyons MS

    更新日期:2011-07-01 00:00:00

  • Latex allergy: a patient and health care system emergency.

    abstract::Latex allergy, an IgE-mediated reaction to proteins retained in finished natural rubber latex products, has become one of the most pervasive problems in medicine. Latex allergy has resulted in death, progressive asthma, severe food allergy from cross-reactivity, and disability of health care professionals with the acc...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0196-0644(98)70073-3

    authors: Kelly KJ,Walsh-Kelly CM

    更新日期:1998-12-01 00:00:00

  • Hands-Only Cardiopulmonary Resuscitation Education: A Comparison of On-Screen With Compression Feedback, Classroom, and Video Education.

    abstract:STUDY OBJECTIVE:We compare 3 methods of hands-only cardiopulmonary resuscitation (CPR) education, using performance scores. A paucity of research exists on the comparative effectiveness of different types of hands-only CPR education. This study also includes a novel kiosk approach that has not previously been studied, ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.annemergmed.2018.09.026

    authors: Heard DG,Andresen KH,Guthmiller KM,Lucas R,Heard KJ,Blewer AL,Abella BS,Gent LM,Sasson C

    更新日期:2019-06-01 00:00:00

  • High-dose hydrocortisone hemisuccinate in scorpion envenomation.

    abstract:STUDY OBJECTIVE:Scorpion envenomation is a common life-threatening hazard in tropical and subtropical countries. Standard treatment is not clearly defined. Many therapies, such as steroids, are prescribed without experimental justification. We sought to assess the efficacy of systematic administration of intravenous hy...

    journal_title:Annals of emergency medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0196-0644(97)70105-7

    authors: Abroug F,Nouira S,Haguiga H,Elatrous S,Belghith M,Boujdaria R,Touzi N,Bouchoucha S

    更新日期:1997-07-01 00:00:00

  • Pediatric bacterial meningitis: is prior antibiotic therapy associated with an altered clinical presentation?

    abstract:STUDY HYPOTHESIS:The clinical features of children treated with oral antibiotics before the diagnosis of bacterial meningitis differ from those who receive no antibiotics. DESIGN:Retrospective case series. SETTING:University medical center. PARTICIPANTS:Two hundred fifty-eight children 24 months old or younger with ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(05)80149-0

    authors: Rothrock SG,Green SM,Wren J,Letai D,Daniel-Underwood L,Pillar E

    更新日期:1992-02-01 00:00:00

  • Experience with a mobile coronary care unit in Brisbane.

    abstract::We examined the performance of a hospital-based mobile coronary care unit staffed by emergency physicians, coronary care nurses, and ambulance personnel in a metropolitan setting (Brisbane, Australia). Our unit attended 2,260 calls during 18 months of operation. Standard dispatched ambulances arrived first to 78% of t...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(89)80462-7

    authors: Bett JH

    更新日期:1989-09-01 00:00:00

  • Premedication With Midazolam or Haloperidol to Prevent Recovery Agitation in Adults Undergoing Procedural Sedation With Ketamine: A Randomized Double-Blind Clinical Trial.

    abstract:STUDY OBJECTIVE:We evaluate the effect of midazolam and haloperidol premedication for reducing ketamine-induced recovery agitation in adult patients undergoing procedural sedation. We also compare physician satisfaction and recovery time. METHODS:We randomized emergency department patients older than 18 years who need...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.annemergmed.2018.11.016

    authors: Akhlaghi N,Payandemehr P,Yaseri M,Akhlaghi AA,Abdolrazaghnejad A

    更新日期:2019-05-01 00:00:00

  • When Safety Event Reporting Is Seen as Punitive: "I've Been PSN-ed!"

    abstract:STUDY OBJECTIVE:Reporting systems are designed to identify patient care issues so changes can be made to improve safety. However, a culture of blame discourages event reporting, and reporting seen as punitive can inhibit individual and system performance in patient safety. This study aimed to determine the frequency an...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2020.06.048

    authors: Feeser VR,Jackson AK,Savage NM,Layng TA,Senn RK,Dhindsa HS,Santen SA,Hemphill RR

    更新日期:2020-08-14 00:00:00

  • Cardiac arrest witnessed by prehospital personnel: intersystem variation in initial rhythm as a basis for a proposed extension of the Utstein recommendations.

    abstract:STUDY OBJECTIVE:To test the hypothesis that intersystem variation in initial rhythm among EMS-witnessed arrests is of sufficient magnitude to warrant standardization of survival by creation of an Utstein-style denominator of EMS-witnessed ventricular fibrillation (VF). METHODS:We conducted a planned subset analysis of...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(97)70115-x

    authors: Gallagher EJ,Lombardi G,Gennis P

    更新日期:1997-07-01 00:00:00

  • An assessment of the incremental value of the ABCD2 score in the emergency department evaluation of transient ischemic attack.

    abstract:STUDY OBJECTIVE:We study the incremental value of the ABCD2 score in predicting short-term risk of ischemic stroke after thorough emergency department (ED) evaluation of transient ischemic attack. METHODS:This was a prospective observational study of consecutive patients presenting to the ED with a transient ischemic ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2010.07.001

    authors: Stead LG,Suravaram S,Bellolio MF,Enduri S,Rabinstein A,Gilmore RM,Bhagra A,Manivannan V,Decker WW

    更新日期:2011-01-01 00:00:00

  • Ventricular arrhythmias during treatment for acute asthma.

    abstract::A double-blind, randomized study was performed to determine the occurrence of ventricular arrhythmias in acute asthma patients treated with epinephrine, aminophylline, or both in combination. Sixty patients were studied with Holter monitoring during the 90-minute study period. There was no statistical difference among...

    journal_title:Annals of emergency medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0196-0644(86)80428-0

    authors: Emerman CL,Crafford WA,Vrobel TR

    更新日期:1986-06-01 00:00:00

  • Near-fatal intoxication by 1, 1, 1-trichloroethane.

    abstract::This report describes a case of near-fatal intoxication following accidental exposure to 1, 1, 1-trichloroethane in a child. This solvent, generally safe, is widely used to 1, 1, 1-trichloroethane in a child. This solvent, generally safe, is widely used in industrial and domestic preparations. Exposure to high levels ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(81)80011-x

    authors: Gerace RV

    更新日期:1981-10-01 00:00:00

  • Improved outcomes in patients with acute allergic syndromes who are treated with combined H1 and H2 antagonists.

    abstract:STUDY OBJECTIVE:Although the addition of H(2) blockers to H(1) antagonists has been promoted for use in anaphylaxis, there have been no large studies establishing the advantage of this approach in treating acute allergic syndromes. In this study we tested the hypothesis that combined H(1) and H(2) blockage results in i...

    journal_title:Annals of emergency medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1067/mem.2000.109445

    authors: Lin RY,Curry A,Pesola GR,Knight RJ,Lee HS,Bakalchuk L,Tenenbaum C,Westfal RE

    更新日期:2000-11-01 00:00:00

  • Limitation on effectiveness of rapid defibrillation by emergency medical technicians in a rural setting.

    abstract::First-responding emergency medical technicians (EMTs) trained to defibrillate have been shown to increase survival from prehospital ventricular fibrillation (VF) almost fourfold in Washington's King County. Using Nebraska ambulance rescue run data from 1982 and published information relating ambulance response time to...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(84)80331-5

    authors: Ornato JP,McNeill SE,Craren EJ,Nelson NM

    更新日期:1984-12-01 00:00:00

  • A randomized, controlled trial of the use of music during laceration repair.

    abstract:STUDY OBJECTIVES:To determine whether music significantly reduces the pain and anxiety associated with laceration repair in the emergency department. PARTICIPANTS AND SETTING:Adult patients presenting to the ED at an urban teaching hospital for laceration repair. Exclusion criteria included patients less than 18 years...

    journal_title:Annals of emergency medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0196-0644(05)81652-x

    authors: Menegazzi JJ,Paris PM,Kersteen CH,Flynn B,Trautman DE

    更新日期:1991-04-01 00:00:00

  • Graduated driver licensing in Utah: is it effective?

    abstract:STUDY OBJECTIVE:We seek to examine the effectiveness of the graduated driver licensing system in Utah by determining whether crash rates of 16-year-old drivers decreased after graduated driver licensing implementation. METHODS:We studied 16-year-old-driver crashes using statewide motor vehicle crash data probabilistic...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2004.10.007

    authors: Hyde LK,Cook LJ,Knight S,Olson LM

    更新日期:2005-02-01 00:00:00

  • Survival and neurologic outcome after cardiopulmonary resuscitation with four different chest compression-ventilation ratios.

    abstract:STUDY OBJECTIVE:The optimal ratio of chest compressions to ventilations during cardiopulmonary resuscitation (CPR) is unknown. We determine 24-hour survival and neurologic outcome, comparing 4 different chest compression-ventilation CPR ratios in a porcine model of prolonged cardiac arrest and bystander CPR. METHODS:F...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1067/mem.2002.129507

    authors: Sanders AB,Kern KB,Berg RA,Hilwig RW,Heidenrich J,Ewy GA

    更新日期:2002-12-01 00:00:00

  • Intravenous access during out-of-hospital emergency care of noninjured patients: a population-based outcome study.

    abstract:STUDY OBJECTIVE:Advanced, out-of-hospital procedures such as intravenous access are commonly performed by emergency medical services (EMS) personnel, yet little evidence supports their use among noninjured patients. We evaluate the association between out-of-hospital, intravenous access and mortality among noninjured, ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2011.07.021

    authors: Seymour CW,Cooke CR,Hebert PL,Rea TD

    更新日期:2012-04-01 00:00:00

  • Emergency department management and 1-year outcomes of patients with atrial flutter.

    abstract:STUDY OBJECTIVE:Atrial flutter is a common arrhythmia seen in the emergency department (ED), yet there is little research describing its management and outcomes. We analyze the success and safety of treatment of ED patients with atrial flutter. METHODS:This was a retrospective cohort study obtained by searching the ED...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2010.09.027

    authors: Scheuermeyer FX,Grafstein E,Heilbron B,Innes G

    更新日期:2011-06-01 00:00:00

  • Delayed treatment of serious decompression sickness.

    abstract::We report the cases of three patients with residual symptoms from diving decompression sickness, each of whom presented to a recompression chamber three to seven days following original exposure. All three had complete resolution of symptomatology despite the delayed treatment. The late resolution of symptoms is evide...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(85)80450-9

    authors: Myers RA,Bray P

    更新日期:1985-03-01 00:00:00

  • An emergency department-based randomized trial of nonbronchoscopic bronchoalveolar lavage for early pathogen identification in severe community-acquired pneumonia.

    abstract:STUDY OBJECTIVES:Many patients with community-acquired pneumonia are treated empirically without an aggressive search for causative pathogens, an approach adopted largely because of the costs and difficulties encountered during efforts to identify the causative organisms. Blood and sputum cultures are not sensitive, an...

    journal_title:Annals of emergency medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1067/mem.2001.118014

    authors: Rodriguez RM,Fancher ML,Phelps M,Hawkins K,Johnson J,Stacks K,Rossini T,Way M,Holland D

    更新日期:2001-10-01 00:00:00