Abstract:
:In the present work fluctuations of number of ligands adsorbed on macromolecule are investigated. We have taken into account the adsorption and desorption of ligands under the circumstance of some adsorption centers fluctuations affected by medium fluctuation. The correlation function and spectral density of number of ligands adsorbed on macromolecule are calculated. The properties of these fluctuations which allow identifying a noisemaker are determined. It has been shown, thatfas andsluggis adsorption can be distinguished by properties of dispersion and spectral density. It has been also shown, that comparison of experimental and theoretical correlation functions (or spectral densities) allows to calculate constants of ligand - adsorption center binding and unbinding.
journal_name
J Biomol Struct Dynjournal_title
Journal of biomolecular structure & dynamicsauthors
Arakelyan VB,Haroutiunian SG,Arakelyan HV,Haroutiunian TSdoi
10.1080/07391102.2002.10506829subject
Has Abstractpub_date
2002-08-01 00:00:00pages
135-9issue
1eissn
0739-1102issn
1538-0254pii
d=3011&c=4084&p=11144&do=detailjournal_volume
20pub_type
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