Soft tissue attachment of a filamentous carbon-absorbable polymer tendon and ligament replacement.

Abstract:

:Soft tissue structures can be replaced by a filamentous carbon-polylactic acid polymer tissue scaffold. A successful replacement requires a secure bond between the synthetic material and living soft tissue. This attachment has been investigated in a rabbit model. In 23 male, white New Zealand rabbits, the proximal third of the Achilles tendon of the hind leg was resected. Seventeen of these rabbits received composite tendon implants; six received no implants and served as shams. In all cases, the contralateral limb served as a unoperated control. Biological fixation of the synthetic material to the tendinous and myotendinous tissues of the rabbit gastrocnemius system was achieved. This occurred by ingrowth of soft tissue into the 7 mu carbon fiber network. This bond developed rapidly and was mechanically secure under physiologic loading conditions. The anastomoses' strengths were tested in tension over a 12-week period and compared to the breaking strengths of their contralateral, unoperated gastrocnemius systems and the sham systems. After four weeks, the systems with implants had strengths equivalent to those of the unoperated systems. Sham systems were significantly weaker throughout the test period. Histologically, the ingrowth process was associated with little inflammatory response. The ingrown tissue was found to be highly cellular with collagen oriented longitudinally to the tendon. After 12 weeks, the volume of collagenous tissue making up the regrown tendon section appeared nearly normal. Secure biological fixation of the carbon-polylactic acid scaffold to soft tissues may allow it application in repair or replacement of tendon or ligament deficits.

journal_name

Clin Orthop Relat Res

authors

Aragona J,Parsons JR,Alexander H,Weiss AB

subject

Has Abstract

pub_date

1981-10-01 00:00:00

pages

268-78

issue

160

eissn

0009-921X

issn

1528-1132

pub_type

杂志文章
  • Physiologically significant thromboembolic disease following total hip arthroplasty. A prospective study.

    abstract::A prospective study was performed of 115 patients without previous history of thromboembolic disease undergoing 117 total hip arthroplasties. No prophylactic anticoagulants were used; two patients developed physiologically significant thromboembolic disease. No deaths were encountered. This incidence of 1.7% is signif...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Ogilvie JW,Higgins GL

    更新日期:1982-11-01 00:00:00

  • Joint injury, repair, and remodeling: roles in post-traumatic osteoarthritis.

    abstract::Joint injuries, especially intraarticular fractures, frequently lead to progressive joint degeneration that causes the clinical syndrome of posttraumatic osteoarthritis. Orthopaedists try to prevent this disease by attempting to restore joint congruity, alignment, and stability; however, many patients have crippling j...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:

    authors: Buckwalter JA,Brown TD

    更新日期:2004-06-01 00:00:00

  • Fixation of the femoral head prosthesis with methylmethacrylate.

    abstract::The techniques used in fixation of the femoral prosthesis in total hip replacement are often based on empiricism and raise questions about: venting the medullary canal with a catheter during the insertion of cement; the inclusion of blood into cement during insertion with possible deleterious effects; recementing a pr...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-197509000-00018

    authors: Buerkle AR Jr,Eftekhar NS

    更新日期:1975-09-01 00:00:00

  • Do patients with a failed metal-on-metal hip implant with a pseudotumor present differences in their peripheral blood lymphocyte subpopulations?

    abstract:BACKGROUND:Early adverse tissue reactions around metal-on-metal (MoM) hip replacements, especially pseudotumors, are a major concern. Because the causes and pathomechanisms of these pseudotumors remain largely unknown, clinical monitoring of patients with MoM bearings is challenging. QUESTIONS/PURPOSES:The purpose of ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-015-4466-8

    authors: Catelas I,Lehoux EA,Hurda I,Baskey SJ,Gala L,Foster R,Kim PR,Beaulé PE

    更新日期:2015-12-01 00:00:00

  • Retained bullet removal in civilian pelvis and extremity gunshot injuries: a systematic review.

    abstract:BACKGROUND:Although gunshot injuries are relatively common, there is little consensus about whether retained bullets or bullet fragments should be removed routinely or only in selected circumstances. QUESTIONS/PURPOSES:We performed a systematic review of the literature to answer the following questions: (1) Is bullet ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1007/s11999-013-3260-8

    authors: Riehl JT,Sassoon A,Connolly K,Haidukewych GJ,Koval KJ

    更新日期:2013-12-01 00:00:00

  • Influenza Vaccination Is Not Associated with Increased Number of Visits for Shoulder Pain.

    abstract:BACKGROUND:Shoulder injury from vaccination was approved for automatic compensation from the Vaccine Injury Compensation Program (VICP)-a federal government program started in 1988 to shield the manufacturers of childhood vaccines from liability. The approval was made on the basis of case reports rather than experiment...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/CORR.0000000000001215

    authors: Gonzalez AI,Kortlever JTP,Moore MG,Ring DC

    更新日期:2020-10-01 00:00:00

  • Bone-block iliotibial band reconstruction for anterior cruciate insufficiency. Follow-up note and minimum five-year follow-up period.

    abstract::Sixty-two of 71 patients (87%) who received a bone-block iliotibial band transfer were followed with a minimum follow-up period of five years (range, 5-10 years). Sixteen of the originally studied knees were examined with an average follow-up period of 104 months (range, 90-120 months). A second group of 46 knees was ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Windsor RE,Insall JN

    更新日期:1990-01-01 00:00:00

  • Mobility and contact mechanics of a rotating platform total knee replacement.

    abstract::Despite their increasing clinical use, mobile-bearing total knee replacements have not been well characterized biomechanically. An experimental and finite element analysis was done to assess the mobility and contact mechanics of a widely used rotating platform total knee replacement. Parameters that varied were axial ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-200111000-00004

    authors: Otto JK,Callaghan JJ,Brown TD

    更新日期:2001-11-01 00:00:00

  • Biomechanical study of tibialis anterior tendon transfer.

    abstract::The tibialis anterior tendon transfer has been used in the treatment of recurrent congenital clubfoot and paralytic equinovarus foot deformities in cerebral palsy. This study attempts to determine the optimal site of tibialis anterior tendon insertion for ankle and foot motion and to compare the split and whole tendon...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-199804000-00031

    authors: Hui JH,Goh JC,Lee EH

    更新日期:1998-04-01 00:00:00

  • Treatment of Paget's disease of bone with ethane-1, hydroxy-1,1 diphosphonate (EHDP) at a low dosage (5 mg/kg/day).

    abstract::Paget's disease of bone in 51 patients was treated with ethane-1, hydroxy-1,1 diphosphonate (EHDP) for six months at a dosage of 5 mg/kg/day. Clinically, the analgesic effect on bone pain is clear, with parallel reduction in radioisotope uptake observed by quantitative bone scintigraphy. There is also a reduction of a...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Alexandre CM,Chapuy MC,Vignon E,Edouard C,Johnston CC,Meunier PJ

    更新日期:1983-04-01 00:00:00

  • Age-related bone loss. A hypothesis and initial assessment in mice.

    abstract::The osteopenia associated with advanced age appears to be a universal phenomenon in humans and animals, but the mechanisms by which it occurs are understood incompletely. However, the explanation must lie in an absolute or relative diminution in the level of osteoblastic bone-forming activity when compared with osteoc...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Kahn A,Gibbons R,Perkins S,Gazit D

    更新日期:1995-04-01 00:00:00

  • Psychological aspects of chronic pain.

    abstract::Except in emergencies, the physician's obligation is not to relieve pain, but to diagnose and treat pathology. Psychological factors complicate organic pain, and make the diagnosis of "psychogenic" pain virtually impossible on the basis of psychological tests alone. In acute (short-term) pain, anti-anxiety agents are ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-197711000-00017

    authors: Sternbach RA

    更新日期:1977-11-01 00:00:00

  • Brachial artery laceration with closed posterior elbow dislocation in an eight year old.

    abstract::Elbow dislocations are relatively uncommon in children. Rupture of the brachial artery associated with closed elbow dislocations in children is rare. This is a report of an 8-year-old boy, the youngest patient ever to be reported to have a closed posterior dislocation of the elbow associated with a brachial artery lac...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Manouel M,Minkowitz B,Shimotsu G,Haq I,Feliccia J

    更新日期:1993-11-01 00:00:00

  • Differences in the Risser grading systems in the United States and France.

    abstract:UNLABELLED:A grading system for ossification of the iliac apophysis (Risser sign) came into use in the mid 1950s in the United States and was adopted sometime later with modifications in France and other European countries. Although called by the same name, these systems have important differences that could lead to di...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/01.blo.0000160819.10767.88

    authors: Bitan FD,Veliskakis KP,Campbell BC

    更新日期:2005-07-01 00:00:00

  • Radiation therapy for low-grade soft tissue sarcoma.

    abstract::One hundred eight patients with low-grade soft tissue sarcoma treated at the authors' institution from 1984 to 1999 were reviewed retrospectively. Low-grade sarcomas were defined as those designated as Grade I of III or Grade I or II of IV. Patients who presented with recurrent tumors or who had multiple procedures at...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-200204000-00023

    authors: Mollabashy A,Virkus WW,Zlotecki RA,Berrey BH,Scarborough MT

    更新日期:2002-04-01 00:00:00

  • Outcomes of shoulder arthroplasty in Olmsted County, Minnesota: a population-based study.

    abstract::Most studies on shoulder arthroplasty include a diverse group of patients presenting to a tertiary care center. Little information is available regarding outcomes in a community setting. We reviewed 98 residents (110 shoulders) of Olmsted County, Minnesota who had shoulder arthroplasties from 1976 to 2000. There were ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/01.blo.0000238870.99980.64

    authors: Adams JE,Sperling JW,Schleck CD,Harmsen WS,Cofield RH

    更新日期:2007-02-01 00:00:00

  • Treatment of the infected hip replacement.

    abstract::Selection of the suitable treatment method for an infected hip arthroplasty requires careful assessment of patient-related variables and expected treatment goals. The basic treatment options include antibiotic suppression, open debridement, resection arthroplasty, arthrodesis, reimplantation of another prosthesis, and...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/00003086-200403000-00010

    authors: Hanssen AD,Spangehl MJ

    更新日期:2004-03-01 00:00:00

  • Extended intralesional treatment versus resection of low-grade chondrosarcomas.

    abstract:UNLABELLED:The need for segmental resection versus intralesional treatment of low-grade chondrosarcomas of the appendicular skeleton remains controversial. We hypothesized extended intralesional treatment would equally control malignant disease but with improved functional outcomes and decreased postoperative complicat...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-008-0691-8

    authors: Aarons C,Potter BK,Adams SC,Pitcher JD Jr,Temple HT

    更新日期:2009-08-01 00:00:00

  • Long-term results with a lateral unicondylar replacement.

    abstract:UNLABELLED:While the literature suggests lateral unicondylar knee arthroplasty (UKA) improves function in the short- and medium-term, it is less clear on longer-term function. We asked (1) whether lateral UKA improved longer-term Knee Society scores and return to previous activity level); (2) whether there were any con...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-008-0351-z

    authors: Argenson JN,Parratte S,Bertani A,Flecher X,Aubaniac JM

    更新日期:2008-11-01 00:00:00

  • Blast injury research: modeling injury effects of landmines, bullets, and bombs.

    abstract::Terrorist blasts and landmine injuries have become more common in the past several decades generating thousands of casualties. Preventive and prognostic measures are limited by the lack of knowledge of these complex events. Previous blast research has focused on primary blast injuries that involve the lung, despite mu...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:

    authors: Hayda R,Harris RM,Bass CD

    更新日期:2004-05-01 00:00:00

  • Acetabular Version Increases During Adolescence Secondary to Reduced Anterior Femoral Head Coverage.

    abstract:BACKGROUND:Acetabular version influences joint mechanics and the risk of impingement. Cross-sectional studies have reported an increase in acetabular version during adolescence; however, to our knowledge no longitudinal study has assessed version or how the change in version occurs. Knowing this would be important beca...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/CORR.0000000000000900

    authors: Grammatopoulos G,Jamieson P,Dobransky J,Rakhra K,Carsen S,Beaulé PE

    更新日期:2019-11-01 00:00:00

  • Compression osteotomy of the tibia.

    abstract::Compression osteotomy of the tibia is to allow knee motion postoperatively without case immobilization. Rigid internal stabilization by axial compression and tension band wiring enhances union. The rigid internal stabilization prevents loss of position of the osteotomy, often seen in other techniques. The benchmark fo...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Sprenger TR,Weber BG,Howard FM

    更新日期:1979-05-01 00:00:00

  • Combined Administration of ASCs and BMP-12 Promotes an M2 Macrophage Phenotype and Enhances Tendon Healing.

    abstract:BACKGROUND:Outcomes after intrasynovial tendon repair are highly variable. An intense inflammatory cascade followed by a delayed healing response can cause adhesion formation and repair-site failure that severely impair the function of repaired digits. No effective remedies exist to fully address these issues. Cell- an...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-017-5369-7

    authors: Gelberman RH,Linderman SW,Jayaram R,Dikina AD,Sakiyama-Elbert S,Alsberg E,Thomopoulos S,Shen H

    更新日期:2017-09-01 00:00:00

  • Open fractures of the humerus treated with external fixation.

    abstract::Twenty-three patients with open fractures of the humerus who had been treated with immediate external fixation were reviewed retrospectively. Eighteen patients had adequate followup and were included in this study. Four patients (22%) had Gustilo and Anderson Grade I injury; 1 (5%), Grade II; and 13 (72%), Grade III (...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-199704000-00021

    authors: Mostafavi HR,Tornetta P 3rd

    更新日期:1997-04-01 00:00:00

  • Development of a new Knee Society scoring system.

    abstract:BACKGROUND:The Knee Society Clinical Rating System was developed in 1989 and has been widely adopted. However, with the increased demand for TKA, there is a need for a new, validated scoring system to better characterize the expectations, satisfaction, and physical activities of the younger, more diverse population of ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-011-2152-z

    authors: Noble PC,Scuderi GR,Brekke AC,Sikorskii A,Benjamin JB,Lonner JH,Chadha P,Daylamani DA,Scott WN,Bourne RB

    更新日期:2012-01-01 00:00:00

  • Lengthening of the forearm by the Ilizarov technique.

    abstract::The Ilizarov technique was used for lengthening 13 forearms in 12 patients. The different types of treatment were: lengthening of the radius alone, lengthening of the ulna alone with or without radial head relocation, lengthening of one-bone forearms, lengthening of the radius and ulna to the same extent, and differen...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Villa A,Paley D,Catagni MA,Bell D,Cattaneo R

    更新日期:1990-01-01 00:00:00

  • Delamination cysts: a predictor of acetabular cartilage delamination in hips with a labral tear.

    abstract:UNLABELLED:The treatment and prognosis of labral tears of the hip depend primarily on whether there is concomitant injury of the adjacent acetabular articular cartilage. We asked whether a delamination cyst on the preoperative plain radiographs correlated with delamination of the acetabular articular cartilage at the t...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-008-0564-1

    authors: Gdalevitch M,Smith K,Tanzer M

    更新日期:2009-04-01 00:00:00

  • The incidence and mechanism of transphyseal spread of osteosarcoma of long bones.

    abstract::Although the physeal cartilage is considered resistant to invasion by metaphyseal osteosarcoma, no objective clinical proof exists to support this view. Fourteen cases of osteosarcoma of long bones in patients ranging in age from ten to 19 years with open physes were reviewed to determine the incidence of transphyseal...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Ghandur-Mnaymneh L,Mnaymneh WA,Puls S

    更新日期:1983-07-01 00:00:00

  • Factors in optimizing the learning environment for surgical training.

    abstract::Today's surgeon is required to demonstrate a variety of professional competencies in an increasingly complex environment. Recently, the time available to train this surgeon has started to erode due to external pressures on administrators and faculty. This growing crisis has led to questions about how to optimize learn...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/01.blo.0000224028.93355.8c

    authors: Gofton W,Regehr G

    更新日期:2006-08-01 00:00:00

  • Graft selection in anterior cruciate ligament revision surgery.

    abstract::Revision anterior cruciate ligament surgery can be very demanding. Graft selection for revision surgery is a pivotal part of this procedure. Often, the usual first choice of tissue is not available. Therefore, familiarity with alternative graft sources and understanding their advantages and disadvantages is imperative...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/00003086-199604000-00008

    authors: Ritchie JR,Parker RD

    更新日期:1996-04-01 00:00:00