Reduction in alternative complement pathway mediated C3 conversion following burn injury.

Abstract:

:Studies were performed to further investigate an abnormality of the alternative complement pathway associated with burn injury. C3 conversion by inulin and cobra venom factor was measured in serial serum samples from 18 burned patients and in the sera from 25 normal controls. C3 conversion by both activating substances in the patients' sera was significantly decreased during 50 days postburn in comparison to C3 conversion in the normal sera. The most marked reduction in C3 conversion occurred in patients with large full-thickness injuries and infectious complications. However, the abnormality was not more severe in patients with pneumonia and bacteremia in comparison to patients with bacteremia only. It was also not predictive of fatal outcome resulting from infectious complications. Preliminary evidence was presented to suggest that the abnormality is caused by a serum inhibitor, which has an affinity for cellulose and/or is inactivated by it.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Bjornson AB,Bjornson HS,Altemeier WA

doi

10.1097/00000658-198108000-00018

subject

Has Abstract

pub_date

1981-08-01 00:00:00

pages

224-31

issue

2

eissn

0003-4932

issn

1528-1140

journal_volume

194

pub_type

杂志文章
  • Sensitivity of the canine pancreatic intraductal pressure to subclinical reduction in cholinesterase acitivity.

    abstract::As a continuation of work from this laboratory on anticholinesterase induced pancreatitis, a study of the relationship between reduced serum cholinesterase activity and changes in pancreatic intraductal pressure was undertaken. Pharmakokinetic studies in three dogs revealed rapid reduction in serum cholinesterase acti...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197907000-00002

    authors: Dressel TD,Goodale RL Jr,Hunninghake DB,Borner JW

    更新日期:1979-07-01 00:00:00

  • Desmoid tumors in familial polyposis coli.

    abstract::Desmoid tumors are locally invasive, nonmetastasizing fibrous tumors most frequently seen in patients with familial polyposis coli (FPC). Of 325 patients with FPC treated at the Cleveland Clinic, 29 (8.9%) were found to have a total of 36 desmoid tumors. These tumors occur in young patients (mean age: 29.8 years), par...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198607000-00014

    authors: Jones IT,Jagelman DG,Fazio VW,Lavery IC,Weakley FL,McGannon E

    更新日期:1986-07-01 00:00:00

  • Emergency portacaval shunt for variceal hemorrhage. A prospective study.

    abstract::Emergency portacaval shunt for variceal bleeding is associated with a high operative mortality, particularly if used as a last resort. Because of this, a strong case has been made against emergency shunt. This report describes an experience with emergency portacaval shunt for the treatment of variceal bleeding when us...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198707000-00007

    authors: Villeneuve JP,Pomier-Layrargues G,Duguay L,Lapointe R,Tanguay S,Marleau D,Willems B,Huet PM,Infante-Rivard C,Lavoie P

    更新日期:1987-07-01 00:00:00

  • Serum amylase level on admission in the diagnosis of blunt injury to the pancreas: its significance and limitations.

    abstract:OBJECTIVE:The objective of this study was to elucidate the significance and limitations of serum amylase levels in the diagnosis of blunt injury to the pancreas. SUMMARY BACKGROUND DATA:Several recently published reports of analyses of patients with blunt abdominal trauma have indicated that determination of the serum...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199707000-00010

    authors: Takishima T,Sugimoto K,Hirata M,Asari Y,Ohwada T,Kakita A

    更新日期:1997-07-01 00:00:00

  • Host defense against opportunist microorganisms following trauma. II. Changes in complement and immunoglobulins in patients with abdominal trauma and in septic patients without trauma.

    abstract::Total hemolytic complement (CH50), conversion of C3 by inulin and cobra venom factor (CoVF), and immunochemical levels of Clq, C4, C2, C3, C5, factor B, properdin, C3b inactivator (KAF), and immunoglobulins (Igs) G, A, and M were measured in the sera of ten patients with abdominal trauma and ten medical patients with ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197807000-00017

    authors: Bjornson AB,Altemeier WA,Bjornson HS

    更新日期:1978-07-01 00:00:00

  • Differences in healing of skin wounds caused by burn and freeze injuries.

    abstract::Circular, full-thickness dermal burn- and freeze-produced wounds were produced in rats to compare the difference in healing between the two types of thermal injuries. Contraction did not occur in wounds (n = 30) caused by freezing, while burn wounds (n = 30) contracted to less than one-third of original size by 21 day...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198002000-00019

    authors: Li AK,Ehrlich HP,Trelstad RL,Koroly MJ,Schattenkerk ME,Malt RA

    更新日期:1980-02-01 00:00:00

  • The LeVeen shunt in the elective treatment of intractable ascites in cirrhosis. A prospective study on 140 patients.

    abstract::One hundred and forty patients with an intractable ascites complicating a chronic liver disease received a peritoneovenous shunt (PVS) using the LeVeen valve. Operative mortality was ten per cent but was 25% in patients with severe liver failure. Intraoperative drainage of ascites sharply decreased postoperative compl...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198504000-00014

    authors: Smadja C,Franco D

    更新日期:1985-04-01 00:00:00

  • Risk factors for prolonged length of stay after major elective surgery.

    abstract:OBJECTIVE:Length of stay (LOS) is an important outcome as a marker of resource consumption. Determining which factors increase LOS may provide information on reducing costs and improving the delivery of care. The purpose of this study was to determine the independent association of intraoperative process of care and po...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199908000-00016

    authors: Collins TC,Daley J,Henderson WH,Khuri SF

    更新日期:1999-08-01 00:00:00

  • Studies of the modified venous allograft.

    abstract::Segments of rat inferior vena cava were modified by proteolytic digestion and dialdehyde starch tanning in an attempt to alter their antigenic nature and increase their tensile strength. These tissues were found to retain their ability to sensitize allogeneic recipients in both the intradermal and intra-aortic positio...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197708000-00018

    authors: Perloff LJ,Rowlands DT,Barker CF

    更新日期:1977-08-01 00:00:00

  • Higher Recurrence Rate After Endoscopic Totally Extraperitoneal (TEP) Inguinal Hernia Repair With Ultrapro Lightweight Mesh: 5-Year Results of a Randomized Controlled Trial (TULP-trial).

    abstract:OBJECTIVE:The aim of this study was to determine inguinal hernia recurrence rates 5 years after endoscopic totally extraperitoneal (TEP) inguinal hernia repair when either lightweight or heavyweight mesh was used. BACKGROUND:Recurrence is an important complication of inguinal hernia surgery. Higher recurrence rates of...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0000000000002649

    authors: Roos MM,Bakker WJ,Schouten N,Voorbrood CEH,Clevers GJ,Verleisdonk EJ,Davids PH,Burgmans JP

    更新日期:2018-08-01 00:00:00

  • Modified technique of obturator bypass in failed or infected grafts.

    abstract::The obturator bypass graft operation can be performed in a moderately simplified manner by a technique that allows extension of indications for the procedure beyond situations in which sepsis is present in the groin. Long-term analysis of the results of the cases available for study indicates that the procedure may ve...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198303000-00015

    authors: Pearce WH,Ricco JB,Yao JS,Flinn WR,Bergan JJ

    更新日期:1983-03-01 00:00:00

  • Evolution of the modified Rossetti fundoplication in children: surgical technique and results.

    abstract:OBJECTIVE:To compare the modified Rossetti fundoplication with the classic Nissen. SUMMARY BACKGROUND DATA:The traditional surgical treatment of gastroesophageal reflux in children has been the classic Nissen fundoplication, defined by liver mobilization, crural repair, takedown of short gastric vessels, and floppy wr...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199906000-00003

    authors: Levy MS,Sorrels CW,Wagner CW,Jackson RJ,Barnes RW,Smith SD

    更新日期:1999-06-01 00:00:00

  • Necrotizing pancreatitis: contemporary analysis of 99 consecutive cases.

    abstract:OBJECTIVE:To analyze the impact of a conservative strategy of management in patients with necrotizing pancreatitis, reserving intervention for patients with documented infection or the late complications of organized necrosis. SUMMARY BACKGROUND DATA:The role of surgery in patients with sterile pancreatic necrosis rem...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-200110000-00016

    authors: Ashley SW,Perez A,Pierce EA,Brooks DC,Moore FD Jr,Whang EE,Banks PA,Zinner MJ

    更新日期:2001-10-01 00:00:00

  • Chronic respiratory symptoms and occult gastroesophageal reflux. A prospective clinical study and results of surgical therapy.

    abstract::Seventy-seven patients with a primary complaint of persistent cough, wheezing, and/or recurrent pneumonia were evaluated for the presence of occult gastroesophageal reflux disease. Fifty-four patients (70%) had increased esophageal acid exposure on 24-hour pH monitoring of the distal esophagus. In 28% of these patient...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199003000-00005

    authors: DeMeester TR,Bonavina L,Iascone C,Courtney JV,Skinner DB

    更新日期:1990-03-01 00:00:00

  • Reconstruction for chronic dysfunction of ileoanal pouches.

    abstract:OBJECTIVE:A retrospective review was performed to determine the results after surgical reconstruction for chronic dysfunction of ileal pouch-anal procedures for ulcerative colitis and familial colonic polyposis at a university medical center. METHODS:During the 20-year period from 1978 to 1998, 601 patients underwent ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199902000-00006

    authors: Fonkalsrud EW,Bustorff-Silva J

    更新日期:1999-02-01 00:00:00

  • Adjuvant radiotherapy is associated with increased sexual dysfunction in male patients undergoing resection for rectal cancer: a predictive model.

    abstract:OBJECTIVES:The objectives of this study were to evaluate the effect of radiotherapy (RT) on sexual function in patients undergoing oncologic resection for rectal cancer, and to develop a mathematical model for quantifying the risk of sexual dysfunction through time for this group of patients. METHODS:Data were prospec...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/01.sla.0000183608.24549.68

    authors: Heriot AG,Tekkis PP,Fazio VW,Neary P,Lavery IC

    更新日期:2005-10-01 00:00:00

  • The American Medical Association's Section on Surgery: The Beginnings of the Organization, Professionalization, and Specialization of Surgery in the United States.

    abstract:OBJECTIVE:To explore the founding of the American Medical Association's Section on Surgery in 1859 and how it represented, on a national basis, the beginnings of organized surgery and the formal start of the professionalization and specialization of surgery in the United States. BACKGROUND:The broad social process of ...

    journal_title:Annals of surgery

    pub_type: 传,历史文章,杂志文章

    doi:10.1097/SLA.0000000000001635

    authors: Rutkow I

    更新日期:2017-01-01 00:00:00

  • Donating a Kidney to a Stranger: A Review of the Benefits and Controversies of Unspecified Kidney Donation.

    abstract:OF BACKGROUND DATA:Unspecified kidney donation (UKD) describes living donation of a kidney to a stranger. The practice is playing an increasingly important role within the transplant programme in the United Kingdom, where these donors are commonly used to trigger a chain of transplants; thereby amplifying the benefit d...

    journal_title:Annals of surgery

    pub_type: 杂志文章,评审

    doi:10.1097/SLA.0000000000003855

    authors: Maple H,Draper H,Gogalniceanu P,Burnapp L,Chilcot J,Mamode N

    更新日期:2020-07-01 00:00:00

  • Laparoscopic Heller myotomy versus endoscopic balloon dilatation for the treatment of achalasia: a network meta-analysis.

    abstract:OBJECTIVE:Comparison of short- and long-term effects after laparoscopic Heller myotomy (LHM) and endoscopic balloon dilation (EBD) considering the need for retreatment. BACKGROUND:Previously published studies have indicated that LHM is the most effective treatment for Achalasia. In contrast to that a recent randomized...

    journal_title:Annals of surgery

    pub_type: 杂志文章,meta分析

    doi:10.1097/SLA.0000000000000212

    authors: Schoenberg MB,Marx S,Kersten JF,Rösch T,Belle S,Kähler G,Vassiliou MC,Lüth S,von Renteln D

    更新日期:2013-12-01 00:00:00

  • Perineural invasion and lymph node involvement as indicators of surgical outcome and pattern of recurrence in the setting of preoperative gemcitabine-based chemoradiation therapy for resectable pancreatic cancer.

    abstract:OBJECTIVE:To analyze the histopathological indicators significantly associated with surgical outcome and the pattern of recurrence in the setting of preoperative gemcitabine-based chemoradiation therapy (CRT) and subsequent pancreatectomy. BACKGROUND:Clinicopathological assessment of the resected specimen is an indisp...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e31823d813c

    authors: Takahashi H,Ohigashi H,Ishikawa O,Gotoh K,Yamada T,Nagata S,Tomita Y,Eguchi H,Doki Y,Yano M

    更新日期:2012-01-01 00:00:00

  • Intraoperative gastrointestinal endoscopy.

    abstract::A four year experience with the adaptation of the flexible fiberoptic endoscope to the intraoperative environment is presented in 30 patients. The technique of intraoperative endoscopy was utilized in a wide variety of difficult gastrointestinal surgical problems to include the location of the site and cause of bleedi...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198006000-00004

    authors: Bowden TA Jr,Hooks VH 3rd,Mansberger AR Jr

    更新日期:1980-06-01 00:00:00

  • Risk factors for surgery and postoperative recurrence in Crohn's disease.

    abstract:OBJECTIVE:To assess the impact of possible risk factors on intestinal resection and postoperative recurrence in Crohn's disease (CD) and to evaluate the disease course. SUMMARY BACKGROUND DATA:The results of previous studies on possible risk factors for surgery and recurrence in Crohn's disease have been inconsistent....

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-200001000-00006

    authors: Bernell O,Lapidus A,Hellers G

    更新日期:2000-01-01 00:00:00

  • Fat induced jejunal inhibition of gastric acid secretion in duodenal ulcer patients before and after truncal vagotomy.

    abstract::The effect of intrajejunal infusion of a fat solution on pentagastrin-stimulated (0.5 microgram/kg-hr) gastric acid secretion was studied in five duodenal ulcer patients before and three to five months after truncal vagotomy. Preoperatively mean acid output was reduced from 41 +/- 5.2 meq H+/hr to 15.4 +/- 1.3 meq H+/...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197711000-00005

    authors: Christiansen J

    更新日期:1977-11-01 00:00:00

  • Surgical management of carcinoma of the junction of the main hepatic ducts.

    abstract::Twenty-six patients are reviewed who had primary carcinomas involving the junction of the hepatic ducts. The majority had had an initial procedure of palliative biliary diversion elsewhere and were referred for further treatment. In three cases, en bloc resection of the tumor with total hepatectomy and orthotopic live...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197607000-00012

    authors: Fortner JG,Kallum BO,Kim DK

    更新日期:1976-07-01 00:00:00

  • The Australian and New Zealand Audit of Surgical Mortality-birth, deaths, and carriage.

    abstract:OBJECTIVE:This article outlines the formation of the Australian and New Zealand Audit of Surgical Mortality (ANZASM) and describes its objectives, governance, functioning and challenges. BACKGROUND:A nationwide audit of surgical mortality provides an overview of the leading causes of death in patients who require surg...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000000581

    authors: Raju RS,Guy GS,Majid AJ,Babidge W,Maddern GJ

    更新日期:2015-02-01 00:00:00

  • Human tissue reaction to sutures.

    abstract::Tissue reaction to sutures was studied in 666 specimens obtained from patients from one day to 23 years after operation. Reaction to catgut depends on the stage of absorption and is mainly histocytic in type. Nonabsorbable sutures are encapsulated by a rim of connective tissue, while near the suture histocytes, giant ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197502000-00003

    authors: Postlethwait RW,Willigan DA,Ulin AW

    更新日期:1975-02-01 00:00:00

  • Role of Serum Carcinoma Embryonic Antigen (CEA) Level in Localized Pancreatic Adenocarcinoma: CEA Level Before Operation is a Significant Prognostic Indicator in Patients With Locally Advanced Pancreatic Cancer Treated With Neoadjuvant Therapy Followed by

    abstract:OBJECTIVE:The aim of the study was to identify the prognostic factors before neoadjuvant chemoradiotherapy (NCRT) in the patients with localized PDAC. Furthermore, to identify the post-surgical survival predictors of patients with LAPC. SUMMARY OF BACKGROUND DATA:Surgical resection may occupy an important position in ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000004148

    authors: Kato H,Kishiwada M,Hayasaki A,Chipaila J,Maeda K,Noguchi D,Gyoten K,Fujii T,Iizawa Y,Tanemura A,Murata Y,Kuriyama N,Usui M,Sakurai H,Isaji S,Mizuno S

    更新日期:2020-07-24 00:00:00

  • Hypertonic saline resuscitation of hemorrhagic shock diminishes neutrophil rolling and adherence to endothelium and reduces in vivo vascular leakage.

    abstract:OBJECTIVE:To evaluate the in vivo effects of hypertonic saline (HTS) resuscitation on the interactions of endothelial cells (ECs) and polymorphonuclear neutrophils (PMNs) and vascular permeability after hemorrhagic shock. SUMMARY BACKGROUND DATA:The PMN has been implicated in the pathogenesis of EC damage and organ in...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-200211000-00014

    authors: Pascual JL,Ferri LE,Seely AJ,Campisi G,Chaudhury P,Giannias B,Evans DC,Razek T,Michel RP,Christou NV

    更新日期:2002-11-01 00:00:00

  • Association 'Between Gabapentinoids on the Day of Colorectal Surgery and Adverse Postoperative Respiratory Outcomes.

    abstract:OBJECTIVE:The aim of this study was to determine the association between gabapentinoids on the day of surgery and adverse postoperative outcomes in patients undergoing colorectal surgery in the United States. BACKGROUND:Gabapentinoids, gabapentin and pregabalin, are recommended in multimodal analgesia protocols for ac...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003317

    authors: Ohnuma T,Krishnamoorthy V,Ellis AR,Yan R,Ray ND,Hsia HL,Pyati S,Stefan M,Bryan WE,Pepin MJ,Lindenauer PK,Bartz RR,Raghunathan K

    更新日期:2019-12-01 00:00:00

  • Fifty years' experience with esophageal atresia and tracheoesophageal fistula. Beginning with Cameron Haight's first operation in 1935.

    abstract::Four hundred twenty-six patients with esophageal atresia with or without tracheoesophageal fistula have been primarily cared for at the University of Michigan Medical Center since Cameron Haight's initial experience with this entity. Over the period of observation, the incidence of new cases as well as the number of a...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198610000-00013

    authors: Manning PB,Morgan RA,Coran AG,Wesley JR,Polley TZ Jr,Behrendt DM,Kirsh MM,Sloan HE

    更新日期:1986-10-01 00:00:00