Efficacy of absorption of sublingual and intravenous Cardio-Green.

Abstract:

:To simulate the effect of sublingual injections on pediatric patients, open-chested kid goats were injected sublingually or peripherally with Cardio-Green while being supported by internal cardiac massage. Our study demonstrates that there is statistically a ten-fold lower central blood level after sublingual injection compared to that after use of the peripheral intravenous route. Our experiment casts doubt on whether absorption through the sublingual route is adequate, and shows that if a peripheral intravenous line cannot be started, vigorous attempts should be made to obtain a central line rather than taking valuable time to inject sublingual drugs. Further studies must be done before these results can be applied to clinical situations.

journal_name

Ann Emerg Med

authors

Ordog GJ,Wasserberger J,Jones J,Rouzier R,Elstin D,Balasubramaniam S

doi

10.1016/s0196-0644(84)80005-0

subject

Has Abstract

pub_date

1984-06-01 00:00:00

pages

426-8

issue

6

eissn

0196-0644

issn

1097-6760

pii

S0196-0644(84)80005-0

journal_volume

13

pub_type

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