Meniscal regeneration and postmeniscectomy degenerative joint disease.

Abstract:

:The failure of meniscal regeneration via a fibrous semilunar mold can be correlated with an increased incidence of degenerative joint disease. Experiments on rabbits revealed a statistically significant relationship between the failure of meniscal regeneration and the development of degenerative joint disease, characterized by osteophyte formation, cartilage pitting and erosions, and loss of carbilage proteoglycan. Similar results in limited studies utilizing adult fox hounds supported this observation. In dogs, variation in the extent of tissues resected about the meniscus, including synovectomy, did not inhibit the reformation of a fibrous semilunar mold. No specific "zone of regeneration" responsible for meniscal regeneration was identified.

journal_name

Clin Orthop Relat Res

authors

Elmer RM,Moskowitz RW,Frankel VH

subject

Has Abstract

pub_date

1977-05-01 00:00:00

pages

304-10

issue

124

eissn

0009-921X

issn

1528-1132

pub_type

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