[Comparison of anterior lumbar fusion rates after circumferential fusion using beta-tricalcium phosphate (Cerasorb) versus autologous iliac crest spongiosa].

Abstract:

AIM:The aim of this prospective clinical trial was to analyse the ventral fusion rate following circumferential fusion for degenerative spine disease using a radiolucent carbon fibre cage (Brantigan, Fa. DePuy-Acromed) loaded with either autogeneous bone graft (iliac crest) or with the tricalcium phosphate Cerasorb with PRP (Curasan AG, Kleinostheim, Deutschland). METHODS:In 26 patients (15 female, 11 male, average age: 57.7 years) a circumferential fusion of the lumbar spine was performed (titanium posterior instrumentation and Brantigan, Fa. DePuy-Acromed). Autogeneous bone graft (iliac crest) and Cerasorb-PRP as cage filling substance were randomly assigned to each level in all patients. Anterior fusion was evaluated in a total number of 69 Brantigan cages by radiographs after 3, 6, 9 and 12 months and by CT 1 year after surgery. RESULTS:The evaluation of radiographs resulted in a fusion rate 49 %. This was significantly different from the fusion rate accessed by CT scanning (28 %). None of the Brantigan cages (n = 33) filled with Cerasorb with PRP showed an anterior fusion in the CT while fusion was proven in 19 of 36 (49 %) Brantigan cages loaded with cancellous bone from the iliac crest. CONCLUSION:The use a of cancellous bone from the iliac crest as filling substance for Brantigan cages in circumferential fusion of the lumbar spine leads to a significantly higher anterior fusion rate than Cerasorb with PRP.

journal_name

Z Orthop Unfall

authors

Hagel A,Zeh A,Hein W,Held A,Wohlrab D

doi

10.1055/s-2007-965252

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

488-92

issue

4

eissn

1864-6697

issn

1864-6743

journal_volume

145

pub_type

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