A minute demyelinating lesion causing acute positional vertigo.

abstract：BACKGROUND:Cladribine causes sustained reduction in peripheral T and B cell populations while sparing other immune cells. We determined two populations of dendritic cells (DCs): namely CD1c(+)/CD19(-) (myeloid DCs) and CD303(+)/CD123(+) (plasmacytoid DCs), CD19(+) B lymphocytes, CD3(+) T lymphocytes and CD4(+) or CD8(+...

journal_title：Journal of the neurological sciences

authors： Mitosek-Szewczyk K,Tabarkiewicz J,Wilczynska B,Lobejko K,Berbecki J,Nastaj M,Dworzanska E,Kolodziejczyk B,Stelmasiak Z,Rolinski J

更新日期：2013-09-15 00:00:00

abstract：:Recently described techniques for separating myosin isoenzymes have been adapted for analysis of myosins from diseased and developing human skeletal muscle. The method is highly suitable for analysis of human myosins because only 2 - 3 mg of muscle are required for routine analyses. Human embryonic/foetal myosins are ...

journal_title：Journal of the neurological sciences

authors： Fitzsimons RB,Hoh JF

更新日期：1981-11-01 00:00:00

abstract：INTRODUCTION:The aim of the present systematic review and meta-analysis was to compare the reported ADC values in different meningiomas and to analyze associations between ADC and cell count and proliferation activity in this tumor entity. METHOD:MEDLINE library and SCOPUS database were screened for papers investigati...

journal_title：Journal of the neurological sciences

authors： Meyer HJ,Wienke A,Surov A

更新日期：2020-08-15 00:00:00

abstract：BAKGROUND:Hereditary Spastic paraplegias (HSPs) are a clinically and genetically heterogeneous group of degenerative disorders characterized by progressive spasticity and weakness of the lower limbs. This study aimed to identify causative gene variants in two unrelated consanguineous Pakistani families presented with 2...

journal_title：Journal of the neurological sciences

authors： Bibi F,Efthymiou S,Bourinaris T,Tariq A,Zafar F,Rana N,Salpietro V,Houlden H,Raja GK,SYNaPS Study Group.,Saeed S,Minhas NM

更新日期：2020-04-15 00:00:00

abstract：OBJECTIVE:We carried out a meta-analysis focusing on the relationships between rs1137070 C>T and rs1799836 A>G polymorphisms in the MAO gene as a modifier of Parkinson disease (PD) susceptibility. METHOD:A literature search of the Cochrane Library Database, Web of Science, PubMed, CINAHL, EMBASE, and the Chinese Biome...

journal_title：Journal of the neurological sciences

authors： Sun YX,Wang XH,Xu AH,Zhao JH

更新日期：2014-10-15 00:00:00

abstract：:We studied a 53-year-old woman with progressive weakness of the left arm, gradually spreading to the other limbs. Neurological examination revealed a motor neuron syndrome with paresis, fasciculations and atrophy. Electrophysiological studies showed multiple motor conduction blocks. The anti-GM1 IgM titer was elevated...

journal_title：Journal of the neurological sciences

authors： Veugelers B,Theys P,Lammens M,Van Hees J,Robberecht W

更新日期：1996-03-01 00:00:00

abstract：:To elucidate a possible role of vitamin A in the pathogenesis of Parkinson's disease (PD) we compared serum levels of retinol (vitamin A), measured by HPLC, and the vitamin A/retinol binding protein (RBP) ratio of 42 PD patients (22 males and 20 females, mean age 67.3 +/- 1.34 years) and their respective spouses as co...

journal_title：Journal of the neurological sciences

authors： Jiménez-Jiménez FJ,Molina JA,Fernández-Calle P,Vázquez A,Pondal M,del Ser T,Gómez-Pastor A,Codoceo R

更新日期：1992-08-01 00:00:00

abstract：:The inflammation plays a critical role in the stroke onset and even in the worsening of the lesions. Therefore, the investigation of inflammatory response in the acute stage may contribute to improve the treatment of ischemic stroke. High-sensitive CRP (hsCRP), IL-6 and TNFalpha were measured as inflammatory markers o...

journal_title：Journal of the neurological sciences

authors： Nakase T,Yamazaki T,Ogura N,Suzuki A,Nagata K

更新日期：2008-08-15 00:00:00

abstract：:The findings are reported of various CSF abnormalities, including IgG indices and oligoclonal IgG, in 160 patients with multiple sclerosis of differing diagnostic certainty and 146 patients with other neurological disorders. An abnormal IgG index, defined as the ratio of IgG/albumin in CSF to that in serum, has been f...

journal_title：Journal of the neurological sciences

authors： Perkin GD,Sethi K,Muller BR

更新日期：1983-08-01 00:00:00

abstract：:We have evaluated cortical excitability in nine patients affected by Wilson's disease (WD) using transcranial magnetic (TMS) and electric (TES) cortical stimulation and central silent period (CSP) data. A clinical score was derived from the sum of scores assigned to extrapyramidal, pyramidal and cerebellar signs. All ...

journal_title：Journal of the neurological sciences

authors： Perretti A,Pellecchia MT,Lanzillo B,Campanella G,Santoro L

更新日期：2001-11-15 00:00:00

abstract：:Recent evidence has suggested that Alzheimer's disease may result from an underlying defect of protein catabolism. In an attempt to identify such a defect, we have determined the levels of Ca(2+)-activated proteinase (principally calpain II) and endogenous inhibitor (calpastatin) activity in normal and Alzheimer's dis...

journal_title：Journal of the neurological sciences

authors： Mantle D,Perry EK

更新日期：1991-04-01 00:00:00

abstract：:The physiological and histological changes following injection of 10 microliter of proteinase K into the rat tibial nerve have been compared with those induced by proteinase K and specific inhibitor phenylmethylsulphonyl fluoride (PMSF) and also by rabbit experimental allergic neuritis (EAN) serum. Proteinase K and PM...

journal_title：Journal of the neurological sciences

authors： Westland K,Pollard JD

更新日期：1987-12-01 00:00:00

abstract：:A Finnish family is described with 9 cases of presenile dementia in 3 generations. The mean age at onset was 52 years (range 46--62 years). Progressive dementia, upper motor neuron signs, muscular rigidity, and twitching, irregular tremors were consistent features in the 6 clinically investigated patients and were ass...

journal_title：Journal of the neurological sciences

authors： Haltia M,Kovanen J,Van Crevel H,Bots GT,Stefanko S

更新日期：1979-08-01 00:00:00

abstract：:A 75-year-old woman developed painful legs and moving toes syndrome (PLMT) 16 months after the onset of herpes zoster (HZ) myelitis. Although the scattered extensive lesions due to HZ myelitis were observed to be eccentric near the posterior horn on MRI, these changes had disappeared upon the development of PLMT. Comb...

journal_title：Journal of the neurological sciences

authors： Ikeda K,Deguchi K,Touge T,Sasaki I,Tsukaguchi M,Shimamura M,Komatsu E,Takeuchi H,Kuriyama S

更新日期：2004-04-15 00:00:00

abstract：OBJECTIVE:Characteristic sleep disturbance in patients with Parkinson's disease (PD) was evaluated using a subjective questionnaire called the PD sleep scale (PDSS). In this study we sought to examine the relationship between the results from the PDSS with those from the Pittsburgh Sleep Quality Index (PSQI), the Epwor...

journal_title：Journal of the neurological sciences

authors： Uemura Y,Nomura T,Inoue Y,Yamawaki M,Yasui K,Nakashima K

更新日期：2009-12-15 00:00:00

abstract：:Demonstration of lesion dissemination in space (DIS) and time (DIT) is necessary for the diagnosis of multiple sclerosis (MS) in clinically isolated syndromes (CIS). The McDonald criteria accepted two methods to demonstrate DIS. The fulfillment of at least three of four MRI Barkhof criteria (MRI-BC) or, alternatively,...

journal_title：Journal of the neurological sciences

authors： Villar LM,García-Barragán N,Sádaba MC,Espiño M,Gómez-Rial J,Martínez-San Millán J,González-Porqué P,Alvarez-Cermeño JC

更新日期：2008-03-15 00:00:00

abstract：BACKGROUND:Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (GNE) myopathy, also called distal myopathy with rimmed vacuoles (DMRV) or hereditary inclusion body myopathy (HIBM), is a rare, progressive autosomal recessive disorder caused by mutations in the GNE gene. Here, we examined the relationship b...

journal_title：Journal of the neurological sciences

authors： Mori-Yoshimura M,Monma K,Suzuki N,Aoki M,Kumamoto T,Tanaka K,Tomimitsu H,Nakano S,Sonoo M,Shimizu J,Sugie K,Nakamura H,Oya Y,Hayashi YK,Malicdan MC,Noguchi S,Murata M,Nishino I

更新日期：2012-07-15 00:00:00

abstract：:We followed two cohorts of Amyotrophic Lateral Sclerosis (ALS) patients to examine the survival and prognostic factors of ALS and the impact of selective referral on prognosis of ALS. The first cohort consisted of population-based incident ALS cases from Harris County, Texas, first diagnosed between 1985 and 1988. The...

journal_title：Journal of the neurological sciences

authors： Lee JR,Annegers JF,Appel SH

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:To investigate whether there is a difference in the neuro-autonomic and hemodynamic parameters in patients with postural tachycardia syndrome (POTS) according to onset time of orthostatic tachycardia during the Head-up tilt (HUT) test. METHODS:We retrospectively reviewed neuro-autonomic and hemodynamic data ...

journal_title：Journal of the neurological sciences

authors： Lee H,Kim HA

更新日期：2018-07-15 00:00:00

abstract：:The mirror system includes a group of neurons in the monkey cortex that discharge both when a movement is executed and when that same movement is observed. An equivalent system in humans has been proposed to mediate action and emotion understanding, being therefore related to theory of mind. Theory of mind (TOM) is th...

journal_title：Journal of the neurological sciences

authors： Alegre M,Guridi J,Artieda J

更新日期：2011-11-15 00:00:00

abstract：OBJECTIVE:The purpose of this study is to identify predictors of stroke-related readmissions at 30days on a safety net hospital level and suggest interventions to reduce the number of readmissions. BACKGROUND:Hospital readmissions are an important measure of the quality of health care services. Readmissions indicate u...

journal_title：Journal of the neurological sciences

authors： Parikh S,George P,Wilson K,Rybin D,Hohler AD

更新日期：2018-02-15 00:00:00

abstract：:Ultrastructural alterations were observed in the sciatic nerve of dystrophic mice. Myelin sheaths were abnormal in shape, abruptly ceased beyond a node of Ranvier, leaving the axon naked. These changes were seen in both afferent and efferent nerve fibres. Apparent embryonal Schwann cells and Schwann cells which were a...

journal_title：Journal of the neurological sciences

authors： Okada E,Mizuhira V,Nakamura H

更新日期：1976-08-01 00:00:00

abstract：:Neurocysticercosis commonly presents with seizures, raised intracranial tension and dementia. The unusual location of the cysts may result in uncommon manifestations mimicking a host of neurological disorders. Ten patients with neurocysticercosis with rare clinical presentations have been described in this series. The...

journal_title：Journal of the neurological sciences

authors： Sawhney IM,Singh G,Lekhra OP,Mathuriya SN,Parihar PS,Prabhakar S

更新日期：1998-01-21 00:00:00

abstract：:Thirty-one HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and 34 asymptomatic carriers were studied in order to investigate the presence of anti-lymphocyte antibodies in their sera. 32% of the patients produced allolymphocytotoxic antibodies reactive to peripheral blood lymphocytes (mainl...

journal_title：Journal of the neurological sciences

authors： Godoy AJ,Itoyama Y,Tokunaga K,Hara H,Kawaga Y,Kiyokawa H,Maeda Y,Goto I

更新日期：1994-08-01 00:00:00

abstract：:We have studied the regional distribution of glycoasparagine storage material in the brain in aspartylglycosaminuria, a condition characterized by inherited deficiency of lysosomal N-aspartyl-beta-N-acetylglucosamine amidohydrolase. Gaschromatographic measurements of the main accumulating glycoprotein-derived metaboli...

journal_title：Journal of the neurological sciences

authors： Maury CP,Haltia M,Palo J

更新日期：1981-05-01 00:00:00

abstract：:Cerebral gliomas may cause a reduction of glucose metabolism in the cerebellum contralateral to the tumor side (crossed cerebellar diaschisis, CCD). We investigated whether CCD is related to tumor localization, histological grade, size and tumor biochemistry. Cerebellar glucose metabolism was measured in 44 glioma pat...

journal_title：Journal of the neurological sciences

authors： Otte A,Roelcke U,von Ammon K,Hausmann O,Maguire RP,Missimer J,Müller-Brand J,Radü EW,Leenders KL

更新日期：1998-01-01 00:00:00

abstract：:Acetylcholine (ACh) plays an important role in cognitive function and muscle atonia in rapid eye movement (REM) sleep. This quantitative study used surface electromyography (sEMG) to investigate changes in muscular activity, which may indicate a deficiency of ACh among patients with cognitive impairment. We recruited ...

journal_title：Journal of the neurological sciences

authors： Chen PC,Wu D,Chen CC,Chi NF,Kang JH,Hu CJ

更新日期：2011-06-15 00:00:00

abstract：:Focal spinal cord blood flow was measured in the left dorsal column during left sciatic nerve stimulation, and compared to blood flow in the same area during sciatic nerve inactivity. Blood flow was found to be significantly increased during stimulation. It is suggested that this increased blood flow is a reflection o...

journal_title：Journal of the neurological sciences

authors： Kobrine AI,Evans DE,Rizzoli HV

更新日期：1978-10-01 00:00:00

abstract：:Plasma levels of testosterone, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) after 3 or 6 days of administration of the synthetic androgenic hormone fluoxymesterone (10 mg/day) were measured in 26 patients with X-linked recessive bulbospinal neuronopathy (X-BSNP) and 22 age-matched male controls. The...

journal_title：Journal of the neurological sciences

authors： Sobue G,Doyu M,Morishima T,Mukai E,Yasuda T,Kachi T,Mitsuma T

更新日期：1994-02-01 00:00:00

abstract：:Prolonged-release (PR) fampridine is approved to treat walking impairment in persons with multiple sclerosis (MS); however, treatment benefits may extend beyond walking. MOBILE was a phase 2, 24-week, double-blind, placebo-controlled exploratory study to assess the impact of 10mg PR-fampridine twice daily versus place...

journal_title：Journal of the neurological sciences

authors： Gasperini C,Hupperts R,Lycke J,Short C,McNeill M,Zhong J,Mehta LR

更新日期：2016-11-15 00:00:00