Keratin 19 maintains E-cadherin localization at the cell surface and stabilizes cell-cell adhesion of MCF7 cells.

abstract：:The aim of this study is to examine a novel drop culture model using a biologically inspired self-assembling peptide: hydrogel (RAD16-I, also called PuraMatrix), which produces a nanoscale environment similar to native extracellular matrix (ECM) for a cell line weakly adherent to a plastic surface during cell culture....

journal_title：Cell adhesion & migration

authors： Yoshida D,Teramoto A

更新日期：2007-04-01 00:00:00

abstract：:The heart is the first organ to function during vertebrate development and cardiac progenitors, are among the first cell lineages to be established from mesoderm cells emerging from the primitive streak during gastrulation. Cardiac progenitors have been mapped in the epiblast of pre-streak embryos. In the early chick ...

journal_title：Cell adhesion & migration

authors： Münsterberg A,Yue Q

更新日期：2008-04-01 00:00:00

abstract：:The central nervous system (CNS) acquires its vasculature by angiogenesis, a process consisting of proliferation of endothelial cells in existing blood vessels or vascular plexuses and leading to formation of new blood vessels. Angiogenesis begins early in CNS development and continues throughout life. Prevailing noti...

journal_title：Cell adhesion & migration

authors： Vasudevan A,Bhide PG

更新日期：2008-07-01 00:00:00

abstract：:We compared the in vitro effect of boric acid (BA) versus phenylboronic acid (PBA) on the migration of prostate and breast cancer cell lines and non-tumorigenic cells from the same tissues. Treatment at 24 hours with BA (< or =500 microM) did not inhibit chemotaxis on fibronectin in any cell line. However, treatment o...

journal_title：Cell adhesion & migration

authors： Bradke TM,Hall C,Carper SW,Plopper GE

更新日期：2008-07-01 00:00:00

abstract：:Tor (target of rapamycin) pathway underlies a major signaling mechanism for controlling cell growth and proliferation.(1) Rheb (Ras homolog enriched in brain) is a small GTPase in the Tor pathway.(2-4) Similar to other small GTPases, Rheb cycles between a GTP-bound active state and a GDP-bound inactive state. TSC2 (tu...

journal_title：Cell adhesion & migration

authors： Choi KW,Hsu YC

更新日期：2007-07-01 00:00:00

abstract：:Atherosclerosis is currently the leading factor of death in developed countries. It is now recognized as a chronic immune-inflammatory disease, whose initial stages involve the interaction of leukocytes with the endothelial monolayer. The initial stage of atherosclerosis requires the interplay of various cell adhesion...

journal_title：Cell adhesion & migration

authors： Chi Z,Melendez AJ

更新日期：2007-10-01 00:00:00

abstract：:VEGF-C is a crucial player in lymphangiogenesis. Besides VEGFR-2 and VEGFR-3, it also binds NRP2. NRP2 enhances VEGF-C/VEGFR-3 effects in developmental lymphangiogenesis, but its role in adult and tumoral lymphangiogenesis is not known. In their study, Bagri and colleagues demonstrate that blocking NRP2 results in a d...

journal_title：Cell adhesion & migration

authors： Roth L

更新日期：2008-10-01 00:00:00

abstract：:Cell migration is central to normal physiology in embryogenesis, the inflammatory response and wound healing. In addition, the acquisition of a motile and invasive phenotype is an important step in the development of tumors and metastasis. Arf GTPase-activating proteins (GAPs) are nonredundant regulators of specialize...

journal_title：Cell adhesion & migration

authors： Campa F,Randazzo PA

更新日期：2008-10-01 00:00:00

abstract：:Vascular smooth muscle cell (SMC) migration and proliferation contribute to arterial wound repair and thickening of the intimal layer in atherosclerosis, restenosis and transplant vascular disease. These processes are influenced by cell adhesion to molecules present in the extracellular matrix, and regulated by the in...

journal_title：Cell adhesion & migration

authors： Ho B,Bendeck MP

更新日期：2009-04-01 00:00:00

abstract：:Ischemia-induced ionic imbalance leads to the activation of numerous events including mitochondrial dysfunction and eventual cell death. Dysregulation of mitochondrial Ca(2+) (Ca(2+)(m)) plays a critical role in cell damage under pathological conditions including traumatic brain injury and stroke. High Ca(2+)(m) level...

journal_title：Cell adhesion & migration

authors： Liu Y,Liu XJ,Sun D

更新日期：2009-01-01 00:00:00

abstract：:It is now well established that neuropilins (NRP1 and NRP2), first described as mediators of neuronal guidance, are also mediators of angiogenesis and tumor progression. NRPs are receptors for the class-3 semaphorin (SEMA) family of axon guidance molecules and also for the vascular endothelial growth factor (VEGF) fam...

journal_title：Cell adhesion & migration

authors： Geretti E,Klagsbrun M

更新日期：2007-04-01 00:00:00

abstract：:Polysialic acid (PSA) is a large carbohydrate added post-translationally to the extracellular domain of the Neural Cell Adhesion Molecule (NCAM) that influences its adhesive and other functional properties. PSA-NCAM is widely distributed in the developing nervous system where it promotes dynamic cell interactions, lik...

journal_title：Cell adhesion & migration

authors： Bonfanti L,Theodosis DT

更新日期：2009-01-01 00:00:00

abstract：:It is increasingly clear that melanoma cells modify their environment not only through the release of growth factors (GFs) and cytokines that have autocrine or paracrine effects and strongly modulate the immune response, but also by secreting proteins that become structural or transient components of the extracellular...

journal_title：Cell adhesion & migration

authors： Vallacchi V,Rodolfo M

更新日期：2009-01-01 00:00:00

abstract：:Nucleic acid oligodeoxynucleotides (ODN) are increasingly used in biological research and in clinics where they are used for both diagnostic and therapeutic purposes. In order to increase the stability and efficacy of ODNs, various chemical modifications have been applied to create nucleic acid derivatives that are no...

journal_title：Cell adhesion & migration

authors： Okun E,Lathia JD,Mattson MP

更新日期：2009-07-01 00:00:00

abstract：:Long-term clinical outcomes are dependent on whether carcinoma cells leave the primary tumor site and invade through adjacent tissue. Recent evidence links tissue rigidity to alterations in cancer cell phenotype and tumor progression. We found that rigid extracellular matrix (ECM) substrates promote invasiveness of tu...

journal_title：Cell adhesion & migration

authors： Parekh A,Weaver AM

更新日期：2009-07-01 00:00:00

abstract：:Despite our advanced understanding of primary cancer development and progression, metastasis and the systemic spread of the disease to secondary sites remains the leading cause of cancer-associated death. The metastatic process is therefore a major potential therapeutic target area for cancer researchers and elucidati...

journal_title：Cell adhesion & migration

authors： Timpson P,Serrels A,Canel M,Frame MC,Brunton VG,Anderson KI

更新日期：2009-10-01 00:00:00

abstract：:The glia that reside at the midline of the Drosophila CNS are an important embryonic signaling center and also wrap the axons that cross the CNS. The development of the midline glia (MG) is characterized by migration, ensheathment, subdivision of axon commissures, apoptosis, and the extension of glial processes. All o...

journal_title：Cell adhesion & migration

authors： Crews ST

更新日期：2010-01-01 00:00:00

abstract：:Guidance molecules were first described in the nervous system to control axon outgrowth direction. They are also widely expressed outside the nervous system where they control cell migration, tissue development and establishment of the vascular network. In addition, they are involved in cancer development, tumor angio...

journal_title：Cell adhesion & migration

authors： Nasarre P,Potiron V,Drabkin H,Roche J

更新日期：2010-01-01 00:00:00

abstract：:Epithelial to mesenchymal transition (EMT) is a critical event in embryogenesis and plays a fundamental role in cancer progression and metastasis. Numb has been shown to play an important role in the proper functions of Par protein complex and in cell-cell junctions, both of which are associated with EMT. However, the...

journal_title：Cell adhesion & migration

authors： Wang Z,Li SS

更新日期：2010-04-01 00:00:00

abstract：:B-cell lymphomas, which arise in lymphoid organs, can spread rapidly via the circulatory system and form solid tumors within multiple organs. Rate-limiting steps in this metastatic process may be the adhesion of lymphoma cells to vascular endothelial cells, their exit from the vasculature and their migration to tissue...

journal_title：Cell adhesion & migration

authors： Lin KB,Freeman SA,Gold MR

更新日期：2010-07-01 00:00:00

abstract：:Wound closure and infection control are the primary goal of wound management. A variety of disinfectants and antimicrobial agents are widely available today and routinely achieve infection control. On the contrary, wound closure still remains a challenging goal. Cell adhesion, migration and contraction play significan...

journal_title：Cell adhesion & migration

authors： Lin A,Hokugo A,Nishimura I

更新日期：2010-07-01 00:00:00

abstract：:Single-chain receptors and multi-chain immune recognition receptors (SRs and MIRRs, respectively) represent families of structurally related but functionally different surface receptors expressed on different cells. In contrast to SRs, a distinctive and common structural characteristic of MIRR family members is that t...

journal_title：Cell adhesion & migration

authors： Sigalov AB

更新日期：2010-04-01 00:00:00

abstract：:As a whole, integral membrane proteins represent about one third of sequenced genomes, and more than 50% of currently available drugs target membrane proteins, often cell surface receptors. Some membrane protein classes, with a defined number of transmembrane (TM) helices, are receiving much attention because of their...

journal_title：Cell adhesion & migration

authors： Hubert P,Sawma P,Duneau JP,Khao J,Hénin J,Bagnard D,Sturgis J

更新日期：2010-04-01 00:00:00

abstract：:The major mental disorders, schizophrenia and bipolar disorder are substantially heritable. Recent genomic studies have identified a small number of common and rare risk genes contributing to both disorders and support epidemiological evidence that genetic susceptibility overlaps between them. Prompted by the question...

journal_title：Cell adhesion & migration

authors： Corvin AP

更新日期：2010-10-01 00:00:00

abstract：:During the infiltration process, glioma cells are known to migrate along preexisting anatomical structures such as blood vessels, axonal fiber tracts and the subependymal space, thereby widely invading surrounding CNS tissue. This phenomenon represents a major obstacle for the clinical treatment of these tumours. Seve...

journal_title：Cell adhesion & migration

authors： Dützmann S,Gessler F,Harter PN,Gerlach R,Mittelbronn M,Seifert V,Kögel D

更新日期：2010-10-01 00:00:00

abstract：:Leukocyte chemotaxis plays an essential role in generating and delivering immune responses and is a critical component of inflammation. In order to identify novel genes and pathways important for regulating chemotaxis, we performed an RNAi-based screen and identified several genes involved with vesicle movement and fu...

journal_title：Cell adhesion & migration

authors： Colvin RA,Luster AD

更新日期：2011-01-01 00:00:00

abstract：:The existence of multiple VEGF-A isoforms raised the possibility that they may have distinct functions in tumor growth. We have previously published that VEGF189 and VEGF165 contribute to breast cancer progression and angiogenesis, but VEGF165 induced the most rapid tumor uptake. Since VEGF165 has been described as a ...

journal_title：Cell adhesion & migration

authors： Vintonenko N,Pelaez-Garavito I,Buteau-Lozano H,Toullec A,Lidereau R,Perret GY,Bieche I,Perrot-Applanat M

更新日期：2011-07-01 00:00:00

abstract：:Filopodia are long, slender, actin-rich cellular protrusions, which recently have become a focus of cell biology research because of their proposed roles as sensory and exploratory organelles that allow for "intelligent" cell behavior. Actin nucleation, elongation and bundling are believed to be essential for filopodi...

journal_title：Cell adhesion & migration

authors： Yang C,Svitkina T

更新日期：2011-09-01 00:00:00

abstract：:Recent findings indicate that cannabinoid-altered vocal development involves elevated densities of dendritic spines in a subset of brain regions involved in zebra finch song learning and production suggesting that cannabinoid receptor activation may regulate cell structure. Here we report that activation of zebra finc...

journal_title：Cell adhesion & migration

authors： Soderstrom K,Zhang Y,Wilson AR

更新日期：2012-03-01 00:00:00

abstract：:Phagocytosis is an important component of innate immunity that contributes to the eradication of infectious microorganisms; however, successful bacterial pathogens often evade different aspects of host immune responses. A common bacterial evasion strategy entails the production of toxins and/or effectors that disrupt ...

journal_title：Cell adhesion & migration

authors： Flannagan RS

更新日期：2012-07-01 00:00:00