Abstract:
:Nowadays, the nitrates have been established as carcinogenic components due to the endogenous formation of N-nitroso compounds, however, the consumption of water contaminated with nitrates has only been strongly related to the presence of methemoglobinemia in infants, as an acute effect, leaving out other side effects that demand attention. The thyroid gland takes relevance because it can be altered by many pollutants known as endocrine disruptors, which are agents capable of interfering with the synthesis of hormones, thus far, it is known that nitrates may disrupt the amount of iodine uptake causing most of the time hypothyroidism and affecting the metabolic functions of the organism in all development stages, resulting in an important health burden for the exposed population. Here, this review and update highlighted the impact of consumption of water contaminated with nitrates and effects on the thyroid gland in humans, concluding that nitrates could act as true endocrine disruptor.
journal_name
Int J Environ Health Resjournal_title
International journal of environmental health researchauthors
García Torres E,Pérez Morales R,González Zamora A,Ríos Sánchez E,Olivas Calderón EH,Alba Romero JJ,Calleros Rincón EYdoi
10.1080/09603123.2020.1815664subject
Has Abstractpub_date
2020-08-31 00:00:00pages
1-18eissn
0960-3123issn
1369-1619pub_type
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