Consumption of water contaminated by nitrate and its deleterious effects on the human thyroid gland: a review and update.

Abstract:

:Nowadays, the nitrates have been established as carcinogenic components due to the endogenous formation of N-nitroso compounds, however, the consumption of water contaminated with nitrates has only been strongly related to the presence of methemoglobinemia in infants, as an acute effect, leaving out other side effects that demand attention. The thyroid gland takes relevance because it can be altered by many pollutants known as endocrine disruptors, which are agents capable of interfering with the synthesis of hormones, thus far, it is known that nitrates may disrupt the amount of iodine uptake causing most of the time hypothyroidism and affecting the metabolic functions of the organism in all development stages, resulting in an important health burden for the exposed population. Here, this review and update highlighted the impact of consumption of water contaminated with nitrates and effects on the thyroid gland in humans, concluding that nitrates could act as true endocrine disruptor.

authors

García Torres E,Pérez Morales R,González Zamora A,Ríos Sánchez E,Olivas Calderón EH,Alba Romero JJ,Calleros Rincón EY

doi

10.1080/09603123.2020.1815664

subject

Has Abstract

pub_date

2020-08-31 00:00:00

pages

1-18

eissn

0960-3123

issn

1369-1619

pub_type

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