Abstract：
:In this review we will describe newly developed techniques that are being used to recover levels of motor function after a severe spinal cord injury that have not been observed previously. These new approaches include pharmacological neuromodulation and/or epidural stimulation of the spinal cord circuitries in combination with motor training. By combining the increased levels of excitability of the interneuronal spinal circuitries using these interventions and the ability of the spinal circuitries to interpret and respond appropriately to ongoing complex ensembles of sensory input, the peripheral sensory system can become an effective source for the control of motor function. Similar types of neuromodulation have been shown to enable the brain to regain functional connectivity with the spinal cord circuitries below a clinically complete spinal cord lesion. In fact, some level of voluntary control of movement has been observed in subjects with complete paralysis in the presence of epidural stimulation. The biological mechanisms thought to underlie the recovery of motor function after a severe spinal cord injury are based on decades of research on a wide range of animal models. Fortunately the extensive conservation of neural mechanisms of motor control has provided a window for gaining considerable insight into the mechanisms of recovery of motor function in humans.
journal_name
Eur J Phys Rehabil Medjournal_title
European journal of physical and rehabilitation medicineauthors
Edgerton VR,Roy RRsubject
Has Abstractpub_date
2012-03-01 00:00:00pages
99-109issue
1eissn
1973-9087issn
1973-9095pii
R33122778journal_volume
48pub_type
杂志文章,评审abstract：BACKGROUND:Freezing of speech (FoS) and other repetitive speech behaviours can frequently occur in parkinsonian syndromes, worsening the efficacy of language functioning, hampering social interactions, and thus reducing quality of life. Pharmacological treatment are ineffective and other interventions have not specific...
journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章
doi：
更新日期：2014-10-01 00:00:00
abstract：:The purpose of this article was to describe the use of noninvasive inspiratory and expiratory muscle aids to prevent chest wall deformities including pectus excavatum, to prevent respiratory complications of vertebral surgery, to prevent acute and long-term ventilatory insufficiency and failure in children with paraly...
journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,评审
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更新日期：2010-12-01 00:00:00
abstract：AIM:Since 2007 we have been focusing our attention to EJPRM as the best available clinical evidence as offered by the Cochrane Collaboration. Due to the absence of a specific Rehabilitation Group (only a Field does exist), some reviews in the field of PRM are not easy to find. Consequently, the EJPRM lists and presents...
journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,评审
doi：
更新日期：2009-12-01 00:00:00
abstract：:Chronic respiratory conditions are among the top causes of death and disability. The aim of the paper was to improve Physical and Rehabilitation Medicine (PRM) physicians' professional practice for people with chronic respiratory conditions in order to promote their functioning and to reduce activity limitations and/o...
journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,评审
doi：10.23736/S1973-9087.18.05309-1
更新日期：2018-08-01 00:00:00
abstract：INTRODUCTION:Multiple sclerosis (MS) is a chronic, inflammatory, progressive, disabling autoimmune disease affecting the central nervous system. Symptoms and signs of MS vary widely and patients may lose their ability to walk. To date the benefits of aquatic therapy often used for rehabilitation in MS patients have not...
journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,评审
doi：10.23736/S1973-9087.17.04570-1
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Decreased range of motion is a common secondary complication of motor neuron disease (MND) that can contribute to functional decline and decreased participation in daily activities. AIM:The purpose of this study was to develop and assess the effectiveness of educational brochures and videos aimed at improvi...
journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章
doi：10.23736/S1973-9087.20.06245-0
更新日期：2020-08-03 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,随机对照试验
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更新日期：2016-12-01 00:00:00
abstract：:The translation of scientific knowledge into clinical practice is still not consistently achieved and the Cochrane Knowledge Translation (KT) Strategy, has been developed in response to this issue, as key step in moving from knowledge to action. "Blogshots" are a new means of presenting evidence in a way that can be e...
journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章
doi：10.23736/S1973-9087.18.05313-3
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:Excessive ankle plantar flexion (equinus foot) is a common problem in cerebral palsy (CP) and several treatment options can be considered depending on the equinus type. Few attempts have been made to classify different forms of equinus foot for specific treatment. AIM:This study is aimed at defining equinus...
journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
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journal_title：European journal of physical and rehabilitation medicine
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更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Microcurrent therapy (MCT) is a novel electrotherapy modality with very low current-levels that may reduce pain especially in joints and muscles. AIM:The aim of this study is to explore potential effects of MCT on pain in patients with knee osteoarthritis, to explore effects of different treatment parameter...
journal_title：European journal of physical and rehabilitation medicine
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更新日期：2020-08-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,评审
doi：
更新日期：2016-08-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,评审
doi：
更新日期：2014-12-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,随机对照试验
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更新日期：2010-12-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
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更新日期：2020-04-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章
doi：
更新日期：2009-12-01 00:00:00
abstract：:The World Health Organization's International Classification of Functioning, Disability and Health (ICF) has provided a new foundation for our understanding of health, functioning, and disability. However, different challenges have to be addressed during its implementation process. The objective of this paper is to ad...
journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,评审
doi：
更新日期：2008-09-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章
doi：
更新日期：2011-09-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章
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更新日期：2013-12-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章
doi：
更新日期：2016-10-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,随机对照试验
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更新日期：2014-02-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,评审
doi：
更新日期：2008-03-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
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更新日期：2019-04-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章
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更新日期：2019-04-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:Coronavirus disease 2019 (COVID-19) pandemic is quickly spreading, putting under heavy stress health systems worldwide and especially Intensive Care Units (ICU). Rehabilitation Units have a crucial role in reducing disability in order to reintroduce patients in the community. AIM:The aim of this study is to...
journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章
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更新日期：2020-10-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,meta分析,评审
doi：
更新日期：2014-02-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,随机对照试验
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更新日期：2013-06-01 00:00:00
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journal_title：European journal of physical and rehabilitation medicine
pub_type： 杂志文章,评审
doi：
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