Endoscopic hemostasis by local injection of epinephrine and polidocanol in bleeding ulcer. A prospective randomized trial.

Abstract:

:The present prospective randomized trial has been carried out to assess the efficacy of the endoscopic injection of epinephrine plus polidocanol, in the prompt treatment of upper gastrointestinal bleeding due to peptic lesions. Over a period of one year, 72 patients were admitted to the study. Thirty-six of these underwent endoscopic treatment (group A), while the others received medical treatment (group B). Definitive hemostasis was achieved in 29 patients in group A, and in 21 in group B (p less than 0.05). Seven patients in group A and 12 in group B underwent emergency surgery for persistent or recurrent bleeding (p = NS). Three patients from group B received endoscopic treatment owing to relative surgical contraindications. It was successful in all of them. Patients from group A needed a significantly lower number of units of packed red cells (p less than 0.05). Our results show that it is justified to employ endoscopic injection as the first therapeutic step in upper GI bleeding due to peptic gastroduodenal lesions.

journal_name

Endoscopy

journal_title

Endoscopy

authors

Balanzó J,Sainz S,Such J,Espinós JC,Guarner C,Cussó X,Monés J,Vilardell F

doi

10.1055/s-2007-1013023

subject

Has Abstract

pub_date

1988-11-01 00:00:00

pages

289-91

issue

6

eissn

0013-726X

issn

1438-8812

journal_volume

20

pub_type

临床试验,杂志文章,随机对照试验
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    更新日期:2015-02-01 00:00:00

  • Endoscopic treatment of scar stenosis in the upper GI tract.

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    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1010687

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    journal_title:Endoscopy

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  • Efficacy of precutting endoscopic mucosal resection with full or partial circumferential incision using a snare tip for difficult colorectal lesions.

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  • Confocal laser scanning fluorescence microscopy for in vivo determination of microvessel density in Barrett's esophagus.

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    journal_title:Endoscopy

    pub_type: 临床试验,杂志文章

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    pub_type: 杂志文章,多中心研究

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    journal_title:Endoscopy

    pub_type: 杂志文章,meta分析

    doi:10.1055/s-2003-42614

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    更新日期:2003-10-01 00:00:00

  • Endoscopy-assisted emergency treatment of gastroduodenal and pancreatobiliary ascariasis.

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  • Endoscopic gallstone extraction following hydrostatic balloon dilatation of stricture in the common bile duct.

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    doi:10.1055/s-2007-1018488

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    doi:10.1055/s-2004-814533

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    更新日期:2004-07-01 00:00:00

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    pub_type:

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