A phenolic acid phenethyl urea derivative protects against irradiation-induced osteoblast damage by modulating intracellular redox state.

abstract：:Many regions of the adult central nervous system contain cycling cells. Such cells comprise a relatively small fraction of the total population of the CNS. Work over decades has attempted to determine the normal fates of these cells and their fates under pathological conditions. The recent interest in "stem" cells and...

journal_title：Journal of cellular biochemistry

authors： Goldman JE

更新日期：2003-01-01 00:00:00

abstract：:Recombinant adenovirus serotype 5 (Ad5) vectors have been studied extensively in preclinical gene therapy models and in a range of clinical trials. However, innate immune responses to adenovirus vectors limit effectiveness of Ad5 based therapies. Moreover, extensive pre-existing Ad5 immunity in human populations will ...

journal_title：Journal of cellular biochemistry

authors： Zaiss AK,Machado HB,Herschman HR

更新日期：2009-11-01 00:00:00

abstract：UNLABELLED:Chemotherapy treatment is the standard in triple negative breast cancers, a cancer subgroup which lacks a specific target. The mechanisms leading to the response, as well as any markers that allow the differentiation between responder and non-responder groups prior to treatment are unknown. In parallel, miRN...

journal_title：Journal of cellular biochemistry

authors： Tormo E,Pineda B,Serna E,Guijarro A,Ribas G,Fores J,Chirivella E,Climent J,Lluch A,Eroles P

更新日期：2015-09-01 00:00:00

abstract：:Beta-dystroglycan (beta-DG) is a widely expressed transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton, and thereby contributing to plasma membrane integrity and signal transduction. We previously observed nuclear localization of beta-DG in cultured cell lines, im...

journal_title：Journal of cellular biochemistry

authors： Lara-Chacón B,de León MB,Leocadio D,Gómez P,Fuentes-Mera L,Martínez-Vieyra I,Ortega A,Jans DA,Cisneros B

更新日期：2010-06-01 00:00:00

abstract：:Common differentially expressed genes (DEGs) in acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) might play critical roles in the pathogenesis and process of leukemia. We collected RNA sequencing (RNA-seq) data of human CLL, ALL samples, and normal peripheral blood CD19+ B cells as well as thy...

journal_title：Journal of cellular biochemistry

authors： Zhang S,Zhang Q,Yin J,Wu X

更新日期：2019-09-01 00:00:00

abstract：:Circular RNA (circRNA) is a new noncoding RNAs and plays an important role in many pathological processes. Recently, studies have shown that circular RNA_PRKCI (circ-PRKCI) regulates cell proliferation and cell migration of tumor cells. Esophageal carcinoma is a highly malignant digestive tract tumor, which is divided...

journal_title：Journal of cellular biochemistry

authors： Shi N,Shan B,Gu B,Song Y,Chu H,Qian L

更新日期：2019-06-01 00:00:00

abstract：:Fluorescent proteins have enabled the color-coding of cells growing in vivo. Noninvasive imaging of cells expressing fluorescent proteins has allowed the real-time determination of the behavior of cancer cells, the progression of infection, the differentiation of stem cells, and interaction of stromal and cancer cells...

journal_title：Journal of cellular biochemistry

authors： Hoffman RM

更新日期：2017-09-01 00:00:00

abstract：:Our previous study demonstrate that vitamin D3 induces the binding of vitamin D3 receptor (VDR) to Sp1 transcription factor and stimulates p27Kip1 expression via the Sp1 consensus sequences in the promoter. Both VDR and Sp1 are transcriptional activators, it is unclear which protein functions as the transcription comp...

journal_title：Journal of cellular biochemistry

authors： Cheng HT,Chen JY,Huang YC,Chang HC,Hung WC

更新日期：2006-08-15 00:00:00

abstract：:We previously reported that prostaglandin F2 alpha (PGF2 alpha) receptor is coupled to pertussis toxin (PTX)-sensitive GTP-binding protein (G protein) in osteoblast-like MC3T3-E1 cells [Miwa et al. (1990): Biochem Biophys Res Commun 171:1229-1235]. In the present study, we examined the effect of PGF2 alpha on the acti...

journal_title：Journal of cellular biochemistry

authors： Kozawa O,Suzuki A,Kotoyori J,Tokuda H,Watanabe Y,Ito Y,Oiso Y

更新日期：1994-07-01 00:00:00

abstract：:Procollagen (Type I) contains a noncollagenous COOH-terminal propeptide (C-propeptide) hypothesized to be important in directing chain association and alignment during assembly. We previously expressed human pro-alpha2(I) cDNA in rat liver epithelial cells, W8, that produce only pro-alpha1(I) trimer collagen (Lim et a...

journal_title：Journal of cellular biochemistry

authors： Lim AL,Doyle SA,Balian G,Smith BD

更新日期：1998-11-01 00:00:00

abstract：:We previously identified human CAP, a homolog of the yeast adenylyl cyclase-associated protein. Previous studies suggest that the N-terminal and C-terminal domains of CAP have distinct functions. We have explored the interactions of human CAP with various proteins. First, by performing yeast two-hybrid screens, we hav...

journal_title：Journal of cellular biochemistry

authors： Hubberstey A,Yu G,Loewith R,Lakusta C,Young D

更新日期：1996-06-01 00:00:00

abstract：:We examined the mRNA expression of scleraxis, a non-myogenic helix-loop-helix type transcription factor in C2C12 myogenic cells. Scleraxis mRNA has been shown to be expressed in sclerotome and perichondrium of the embryos. We found that C2C12 cells express 1.2 kb scleraxis mRNA constitutively. Since BMP was reported t...

journal_title：Journal of cellular biochemistry

authors： Liu Y,Nifuji A,Tamura M,Wozney JM,Olson EN,Noda M

更新日期：1997-10-01 00:00:00

abstract：:We have examined the effect of polyoma virus infection of primary mouse embryo cells on the tyrosyl kinase activity associated with the cellular src gene product, pp60c-src. The results of our studies demonstrate that infection of mouse cells with wild-type polyoma virus or viral mutants capable of transforming rodent...

journal_title：Journal of cellular biochemistry

authors： Bolen JB,Lewis AM Jr,Israel MA

更新日期：1985-01-01 00:00:00

abstract：:Two monoclonal antibodies that cause changes in the morphology of cultured myogenic cells are described. Antibody JG9 causes myoblasts to round up and causes myotubes to become thin, cable-like structures with multiple round swellings. Antibody JG22 causes both myoblasts and myotubes to become round refractile cells p...

journal_title：Journal of cellular biochemistry

authors： Greve JM,Gottlieb DI

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Curcuminoids are polyphenols with documented anti-inflammatory activity and has been shown to improve the symptoms of several inflammatory diseases. We aimed to evaluate the effectiveness of a nanoformulation of curcuminoids in the treatment of ulcerative colitis. METHODS:This randomized double-blinded cont...

journal_title：Journal of cellular biochemistry

authors： Masoodi M,Mahdiabadi MA,Mokhtare M,Agah S,Kashani AHF,Rezadoost AM,Sabzikarian M,Talebi A,Sahebkar A

更新日期：2018-11-01 00:00:00

abstract：:"microRNA-383 suppresses the PI3K-AKT-MTOR signaling pathway to inhibit development of cervical cancer via downregulating PARP2," by Peng Teng, Yan Jiao, Min Hao, Xin Tang, J Cell Biochem. 2018; 5243-5252: The above article, published online on 13 December 2017 in Wiley Online Library (https://onlinelibrary.wiley.com/...

journal_title：Journal of cellular biochemistry

authors：

更新日期：2021-01-01 00:00:00

abstract：:Adipose tissue is critical in obesity and type II diabetes. Blocking of adipocyte differentiation is one of the anti-obesity strategies targeting on strong rise in fat storage and secretion of adipokine(s). However, the molecular basis of adipocyte differentiation and its regulation remains obscure. Therefore, we expo...

journal_title：Journal of cellular biochemistry

authors： Ye F,Zhang H,Yang YX,Hu HD,Sze SK,Meng W,Qian J,Ren H,Yang BL,Luo MY,Wu X,Zhu W,Cai WJ,Tong JB

更新日期：2011-10-01 00:00:00

abstract：:Colorectal cancer (CRC), regardless of standard procedures of treatment and screening, is still considered one of the deadliest cancers in the Western world, and in economically developed Asian countries, especially Iran. The current study was undertaken to investigate whether changes in the level of Cripto-1 (CR-1) e...

journal_title：Journal of cellular biochemistry

authors： Igder S,Mohammadiasl J,Azadpour S,Mansouri E,Ashktorab H,Mokarram P

更新日期：2020-04-01 00:00:00

abstract：:Malignant gliomas, the most common subtype of primary brain tumors, are characterized by high proliferation, great invasion, and neurological destruction and considered to be the deadliest of human cancers. Analgesic-antitumor peptide (AGAP), one of scorpion toxic polypeptides, has been shown to have antitumor activit...

journal_title：Journal of cellular biochemistry

authors： Zhao Y,Cai X,Ye T,Huo J,Liu C,Zhang S,Cao P

更新日期：2011-09-01 00:00:00

abstract：:Weightlessness induces bone loss in humans and animal models. We employed the NASA-approved Rotating Wall Vessel bioreactor (RWV) to develop osteoblast-like cell cultures under microgravity and evaluate osteoblast phenotype and cell function. Rat osteoblast-like cell line (ROS.SMER#14) was grown in the RWV at a calcul...

journal_title：Journal of cellular biochemistry

authors： Rucci N,Migliaccio S,Zani BM,Taranta A,Teti A

更新日期：2002-01-01 00:00:00

abstract：:Hepatitis B virus (HBV) is the most common of the hepatitis viruses that cause chronic liver infections in humans and it is considered a major global health problem. However, the mechanisms of HBV replication are complex and not yet fully understood. In this study, the HBV DNA-transfected HepG2.2.15 cell line and its ...

journal_title：Journal of cellular biochemistry

authors： Tong SW,Yang YX,Hu HD,An X,Ye F,Ren H,Li SL,Zhang DZ

更新日期：2013-01-01 00:00:00

abstract：:Enhanced phosphorylation of the ribosomal protein s6 kinase, p70(s6k), and the translational repressor, 4E-BP1, are associated with either insulin-induced or amino acid-induced protein synthesis. Hyperphosphorylation of p70(s6k) and 4E-BP1 in response to insulin or amino acids is mediated through the mammalian target ...

journal_title：Journal of cellular biochemistry

authors： Pham PT,Heydrick SJ,Fox HL,Kimball SR,Jefferson LS Jr,Lynch CJ

更新日期：2000-09-07 00:00:00

abstract：:The present study investigates the direct action of 5-methoxytryptophol (5-MTX) in both MC3T3-E1 and RAW264.7 cells and compares it with melatonin (MEL), another 5-methoxyindol known to play a significant role on bone metabolism. We first screened increasing doses of both 5-MTX and MEL to determine their effect on met...

journal_title：Journal of cellular biochemistry

authors： Satué M,Ramis JM,del Mar Arriero M,Monjo M

更新日期：2015-04-01 00:00:00

abstract：:The contribution of proximal tubules (PT) to albumin uptake is now well recognized, however, its regulation is understudied area. There are reports suggesting that insulin resistance is associated with the development of albuminuria in nondiabetic individuals. We have previously reported reduced insulin receptor (IR) ...

journal_title：Journal of cellular biochemistry

authors： Kumari M,Sharma R,Pandey G,Ecelbarger CM,Mishra P,Tiwari S

更新日期：2019-06-01 00:00:00

abstract：:There has been an impressive emergence of mass spectrometry based technologies applied toward the study of proteins. Equally notable is the rapid adaptation of these technologies to biomedical approaches in the realm of clinical proteomics. Concerted efforts toward the elucidation of the proteomes of organ sites or sp...

journal_title：Journal of cellular biochemistry

authors： Semmes OJ,Malik G,Ward M

更新日期：2006-06-01 00:00:00

abstract：:The Zika virus is a rapidly spreading Aedes mosquito-borne sickness, which creates an unanticipated linkage birth deformity and neurological turmoil. This study represents the use of the combinatorial immunoinformatics approach to develop a multiepitope subunit vaccine using the structural and nonstructural proteins o...

journal_title：Journal of cellular biochemistry

authors： Kumar Pandey R,Ojha R,Mishra A,Kumar Prajapati V

更新日期：2018-09-01 00:00:00

abstract：:In a human lymphoblastoid cell line (Z83) in which rDNA genes on chromosome 22 are amplified but transcribed at a low level, immunocytological studies with antibodies to 5 methylcytidine provided evidence for hypermethylation of the rDNA. The extent of methylation of the 5' flanking sequences of the ribosomal DNA was ...

journal_title：Journal of cellular biochemistry

authors： Dante R,Percy ME,Baldini A,Markovic VD,Miller DA,Rocchi M,Niveleau A,Miller OJ

更新日期：1992-12-01 00:00:00

abstract：:A panel of monoclonal antibodies and conventional antisera directed against desmosomal proteins from bovine muzzle epidermis was used to identify immunologically related proteins from two other bovine stratified squamous epithelia, cornea and esophagus. Desmosome-enriched tissue fractions were prepared from epidermis,...

journal_title：Journal of cellular biochemistry

authors： Giudice GJ,Cohen SM,Patel NH,Steinberg MS

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Acinetobacter baumannii has emerged as a major cause of nosocomial infections. Various resistance mechanisms of A. baumannii against antibiotics have transformed it into a successful nosocomial pathogen. Because of the limited number of available antibiotics, we used a medicinal plant with an antibacterial e...

journal_title：Journal of cellular biochemistry

authors： Hassannejad N,Bahador A,Rudbari NH,Modarressi MH,Parivar K

更新日期：2019-11-01 00:00:00

abstract：:We investigated the role of tetracycline in the transcriptional regulation of matrix metalloproteinases. Using interleukin-1beta (IL-1) induced stromelysin as a model system, we describe the repression of the endogenous stromelysin RNA accumulation, as well as the transcriptional inhibition of various stromelysin prom...

journal_title：Journal of cellular biochemistry

authors： Jonat C,Chung FZ,Baragi VM

更新日期：1996-03-01 00:00:00