Abstract:
INTRODUCTION:Transcranial direct current stimulation (tDCS) has been explored as a neuromodulatory tool to prime motor function in several neurological disorders. Studies using tDCS in amyotrophic lateral sclerosis (ALS) are limited. We investigated the safety, feasibility and effects of long-term tDCS in an individual with ALS. METHODS:A 36-year-old male diagnosed with clinically definite ALS received 12 sessions each of anodal, sham, and cathodal tDCS. Outcome measures included disease progression (revised ALS functional rating scale (ALSFRS-R)), clinical measures of endurance and mobility, and corticomotor excitability. RESULTS:No adverse events or change in disease progression were noticed during the study. Small improvement in gait speed (15% increase) was noticed with anodal tDCS only. CONCLUSIONS:This case study demonstrates the safety and feasibility of long-term facilitatory and inhibitory tDCS on a single participant with ALS. This study serves as a guideline for implementing tDCS in future ALS trials.
journal_name
Physiother Theory Practjournal_title
Physiotherapy theory and practiceauthors
Madhavan S PT, PhD,Sivaramakrishnan A PT, MS,Bond S MS,Jiang QL MDdoi
10.1080/09593985.2018.1443536subject
Has Abstractpub_date
2019-05-01 00:00:00pages
458-463issue
5eissn
0959-3985issn
1532-5040journal_volume
35pub_type
杂志文章abstract::Background and Purpose: The Multiple sclerosis walking scale-12 (MSWS-12) and the Modified Fatigue Impact Scale (MFIS) are two popular outcome measures applied widely for assessing self-perceived walking ability and fatigue in people with multiple sclerosis (PwMS). The present study aimed to examine responsiveness and...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2020.1762267
更新日期:2020-05-20 00:00:00
abstract::Background: Although it has been reported that neurocognitive rehabilitation is effective for improving upper limb function in acute and subacute stroke patients, its effectiveness has not been clarified in community-dwelling chronic stroke patients. Objective: To examine the effect of neurocognitive rehabilitation on...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2020.1861669
更新日期:2020-12-15 00:00:00
abstract::The main goal was to investigate changes in muscle activity and joint moments related to step length (SL) symmetry improvements in individuals poststroke following repeated split-belt treadmill (SBT) walking. Twelve individuals with a first unilateral cerebral stroke presenting initial SL asymmetry (ratio = 1.10-2.05)...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2018.1530708
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Many individuals with stroke express desires to resume activities involving deep knee flexion, such as daily living, work-related, and sports activities. However, training methods for improving deep flexion activities have not commonly been reported in the stroke rehabilitation literature. The pu...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.3109/09593985.2013.850564
更新日期:2014-04-01 00:00:00
abstract::Introduction: To assist with the professional development of physical therapists in Kenya, a post-graduate residency program was developed and implemented in the country.Purpose: The purpose of this study was to explore the influence of residency training on the professional development of physical therapists.Methods:...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2020.1737994
更新日期:2020-03-09 00:00:00
abstract::Introduction: The primary purpose of this study was to examine the feasibility and informativeness of the Patient-Specific Functional Scale (PSFS) for identifying activities that persons with Parkinson disease (PD) self-identified as difficult.Method: Informativeness was investigated by cross-referencing the identifie...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2019.1571134
更新日期:2020-11-01 00:00:00
abstract::Background: Chronic pain management is a challenging area of practice for new graduate physiotherapists entering the workforce. Understanding the readiness and experience of new graduates entering this area of practice is important for informing requirements for preparation for practice.Objective: The aim of this stud...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2019.1692394
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of "breathing control" on sonographic diaphragmatic excursion. METHOD:A prospective, randomized, assessor-blinded study design involving 20 physiotherapy students; ten with knowledge of the breathing control technique (Group BC) and ten without (Group CON). All participants were ask...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章,随机对照试验
doi:10.1080/09593985.2017.1323363
更新日期:2017-07-01 00:00:00
abstract::Background: The majority of patients with chronic kidney disease (CKD) are physically inactive. Simple yet accurate assessment of physical activity is important in identifying those in need of intervention. The 'General Practice Physical Activity Questionnaire' (GPPAQ) is a well-used clinical and research tool, but ha...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2020.1855684
更新日期:2020-12-02 00:00:00
abstract::Background and Purpose: The Groningen Meander Walking time (GMW-sec) test has not been clinically validated as a feasible assessment to test functional mobility skills. The purpose of this study was to determine the concurrent validity of the GMW-sec test with the Timed Up and Go (TUG) test in older adults with dement...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2019.1579285
更新日期:2020-12-01 00:00:00
abstract::Introduction: Fibromyalgia syndrome (FMS) is a chronic musculoskeletal pain and fatigue condition. Despite extensive research, there is currently no known therapy leading to a cure for FMS. Although studies have reported that some patients can regain their health, little is known about their personal process of becomi...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2020.1830454
更新日期:2020-10-07 00:00:00
abstract::Some respiratory muscles work in synergy with the pelvic floor (PF). Pelvic organ prolapse (POP) is characterized by weak PF muscles and has been associated with worse pulmonary ventilation function in women. To date no studies have investigated the association between respiratory muscle strength and POP. This study a...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2019.1642428
更新日期:2019-07-11 00:00:00
abstract::Objective: To determine the effects of an exercise intervention on physical performance and reported fall incidents among individuals living with dementia in nursing homes. Methods: The study was a randomized controlled trial to determine the effect of the physical activity on physical performance and reported fall in...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2019.1594470
更新日期:2021-01-01 00:00:00
abstract::Background: Body mass index, pain, female sex, and age have been reported as predictors of physical activity in patients with lumbar spinal stenosis (LSS). However, no reports have examined the psychological factors associated with physical activity in people with LSS. Purpose: To use psychological assessments to iden...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2020.1855685
更新日期:2020-12-03 00:00:00
abstract::Ashworth Scales are the most widely used tests to assess the severity of muscle spasticity. These scales offer qualitative and subjective information; consequently, there are issues concerning validity and reliability. This article presents the results of a study comparing interrater reliability of the original and of...
journal_title:Physiotherapy theory and practice
pub_type: 临床试验,杂志文章
doi:10.1080/09593980600724188
更新日期:2006-06-01 00:00:00
abstract::Objective: To compare the segmental and extrasegmental hypoalgesic effects of TENS, IFC and Aussie current on pressure pain threshold (PPT) during and after stimulation in healthy subjects. The second objective was to compare the sensory comfort related to electrical stimulation. Material and Methods: 120 healthy subj...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2019.1650857
更新日期:2019-08-12 00:00:00
abstract::Provision of out of regular business hours (OBH) physiotherapy to hospital inpatients is widespread in the hospital setting. This systematic review evaluated the effect of additional OBH physiotherapy services on patient length of stay (LOS), pulmonary complications, discharge destination, discharge mobility status, q...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章,评审
doi:10.1080/09593980601023754
更新日期:2006-12-01 00:00:00
abstract::The aim of this study was to investigate satisfaction with physiotherapy and perception of change following single physiotherapy consultations in a hospital's outpatient service for people with multiple sclerosis (MS) (PwMS). The consultation included assessment, exploration of treatment, information, and instruction ...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.3109/09593985.2011.574782
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To verify effects of kinesio taping (KT) in shoulder subacromial impingement syndrome (SIS) when compared to sham taping applied in the same way with KT. PATIENTS AND METHODS:Patients were randomized as group 1 (n = 21) KT group and group 2 (n = 20) sham-taping group. Taping was applied every three days, thr...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章,随机对照试验
doi:10.1080/09593985.2016.1219434
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:Visual and proprioceptive cues are important for body orientation to maintain correct posture. This study investigated the effects of exercise training on subjective visual, postural, and haptic perception of verticality in patients with scoliosis. SUBJECTS AND METHODS:Thirty-two female adolescents with modera...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章,随机对照试验
doi:10.1080/09593985.2017.1423429
更新日期:2018-08-01 00:00:00
abstract::Background: The mini-Balance Evaluation Systems Test (mini-BESTest) is a valid tool for assessing standing balance in people with spinal cord injury (SCI). Its reliability has not yet been investigated with this population. Objective: To assess the test-retest and inter-rater reliability of the mini-BESTest in adults ...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2019.1622161
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Pain is a common symptom in people with chronic obstructive pulmonary disease (COPD) which negatively influences quality of life and psychological well-being. However, our understanding of how those with COPD interpret the experience of pain is very limited. OBJECTIVES:To explore how individuals with modera...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2018.1425512
更新日期:2018-10-01 00:00:00
abstract::Chronic pain is prevalent in the western world; however fear of pain often has a greater impact than the degree of initial injury. The aim of this study was to explore the relationship between knowledge of the neurophysiology of pain and fear avoidance in individuals diagnosed with chronic pain. Twenty-nine people wit...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.3109/09593985.2015.1138010
更新日期:2016-05-01 00:00:00
abstract::Superior Canal Dehiscence Syndrome (SCDS) causes auditory and vestibular symptoms. Following surgical repair of the dehiscence, patients often experience dizziness and imbalance. This case report describes a postoperative vestibular exercise program, focusing on the principles of central compensation and habituation, ...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2017.1374491
更新日期:2018-02-01 00:00:00
abstract::Study Design: Case Series. Background: Shoulder pain is a prevalent problem in health care. Traditionally, treatment is based on a pathoanatomical diagnosis determined through the use of special tests. The validity of these special tests is questionable and minimal evidence exists to support these tests to guide treat...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2019.1571136
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:Recent evidence has demonstrated that group-based physiotherapy interventions for musculoskeletal pain can have similar clinical outcomes compared to one-to-one treatment. This study qualitatively explored the experiences of individuals who participated in a physiotherapist-led group exercise class for people...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2017.1422208
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Muscle wasting in critical illness has been identified as a major clinical concern which can lead to persistent muscle weakness, impede recovery and limit physical function and quality of life in survivors. Neuromuscular electrical stimulation (NMES) has been suggested as an alternative to active exercise in...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章,评审
doi:10.3109/09593985.2013.811567
更新日期:2014-01-01 00:00:00
abstract:: Background: Physiotherapists (PTs) are responsible for the prevention and promotion of physical and mental health. Their beliefs toward mental illness (MI) are important to disclose stigmatization. Purpose: To investigate the b...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2020.1870251
更新日期:2021-01-21 00:00:00
abstract::The objective of the present study was to compare the effects of continuous ultrasound (CUS) with pulsed ultrasound (PUS) in patients with chronic rhinosinusitis (CRS). In this prospective, randomized, double-blind, parallel group study, 40 patients (10 losses) with CRS participated. Patients received either continuou...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章,随机对照试验
doi:10.3109/09593985.2011.571751
更新日期:2012-02-01 00:00:00
abstract:: Background: In Mechanical Diagnosis and Therapy (MDT), patients with low back pain (LBP) are classified into subgroups to guide a management strategy. A common subgroup where symptoms improve with lumbar extension is labeled posterior derangement syndrome. A less common su...
journal_title:Physiotherapy theory and practice
pub_type: 杂志文章
doi:10.1080/09593985.2018.1488906
更新日期:2020-04-01 00:00:00