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Effect of perioperative complications after endovascular therapy in patients with peripheral artery disease due to femoropopliteal lesions.

Abstract：

OBJECTIVE:Despite wide use, high initial success, and acceptable durability of endovascular therapy (EVT) for femoropopliteal (FP) lesions, the frequency of 30-day perioperative complications (POCs) and their effect on clinical outcomes have not been systematically evaluated, which is the subject of this study. METHODS:We used a multicenter database of 2145 consecutive patients (70% male; overall mean age, 73 ± 9 years) who successfully underwent EVT for FP lesions to investigate independent predictors of POCs (logistic regression analysis) and effect of POCs on prognostic outcomes (Cox proportional regression). RESULTS:POCs were observed in 209 patients (10%). In multivariate logistic regression analysis, body mass index <18.5 kg/m(2), critical limb ischemia, and TransAtlanic Inter-Society Consensus for the Management of Peripheral Arterial Disease class D lesions were independently associated with POCs (adjusted odds ratios [95% confidence intervals], 2.0 [1.3-2.9], 2.5 [1.9-3.3], and 1.6 [1.2-2.1], respectively). After risk stratification of POCs according to the number of these risk factors, the incidence of POCs was higher in the groups with higher scores. Follow-up for >30 days (mean, 2.3 ± 1.8 years) was available for 2079 of 2145 patients. A Cox hazard regression model adjusted for baseline clinical characteristics showed POCs were negatively and independently associated with future occurrence of major adverse limb events (defined as major amputation and major reintervention) or death (hazard ratio [95% confidence interval], 1.6 [1.2-2.1]; P < .05). CONCLUSIONS:Body mass index <18.5 kg/m(2), critical limb ischemia, and TransAtlantic Inter-Society Consensus for the Management of Peripheral Arterial Disease class D lesion were positively associated with POCs after EVT for FP lesions. The occurrence of POCs may adversely affect clinical outcomes in the chronic phase.

journal_name

J Vasc Surg

journal_title

Journal of vascular surgery

authors

Sato K,Iida O,Takahara M,Soga Y,Suzuki K,Tanigawa T,Ito M,Uematsu M

doi

10.1016/j.jvs.2014.12.051

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

1272-7

issue

eissn

0741-5214

issn

1097-6809

pii

S0741-5214(15)00023-3

journal_volume

pub_type

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Effect of perioperative complications after endovascular therapy in patients with peripheral artery disease due to femoropopliteal lesions.