Abstract:
PURPOSE:To explore the clinical features, management, and prognosis of metastatic basal cell carcinoma originating in the orbitofacial region. METHODS:Ten cases of orbitofacial metastatic basal cell carcinoma were identified by searching databases at 2 institutions from 1995 to 2015. A retrospective chart review was performed. Main outcome measures included patient demographics, lesion size, location of metastases, histologic subtype, recurrence rate, time between primary tumor diagnosis and metastasis, perineural invasion, treatment modalities, and survival from time of metastasis. RESULTS:The median tumor size at largest dimension was 3.3 cm (range, 1.9-11.5 cm), and 6 of 10 patients had at least 1 local recurrence before metastasis (range, 0-2 recurrences). The most common sites of metastasis included the ipsilateral parotid gland (n = 6) and cervical lymph nodes (n = 5). Histologic subtypes included infiltrative (n = 5), basosquamous (n = 2), nodular (n = 1), and mixed (n = 1). The median time from primary tumor diagnosis to metastasis was 7.5 years (range, 0-13). The median survival time from diagnosis of metastasis to last documented encounter or death was 5.3 years (range, 7 months-22.8 years). Treatment regimens included surgical excision, radiotherapy, and hedgehog inhibitors. CONCLUSIONS:Based on our findings, the following features may be markers of high risk orbitofacial basal cell carcinoma: 1) increasing tumor size, 2) local recurrence of the primary tumor, 3) aggressive histologic subtype, and 4) perineural invasion. Screening should include close observation of the primary site and tissues in the distribution of regional lymphatics, particularly the parotid gland and cervical lymph nodes.
journal_name
Ophthalmic Plast Reconstr Surgjournal_title
Ophthalmic plastic and reconstructive surgeryauthors
Branson SV,McClintic E,Ozgur O,Esmaeli B,Yeatts RPdoi
10.1097/IOP.0000000000000715subject
Has Abstractpub_date
2017-05-01 00:00:00pages
213-217issue
3eissn
0740-9303issn
1537-2677journal_volume
33pub_type
杂志文章abstract:PURPOSE:To analyze a new bioresorbable orbital implant (open-celled polylactic acid, also known as OPLA). METHODS:The implants were examined macroscopically, with chemical analysis (Fourier transform infrared spectroscopy), and microscopically with scanning electron microscopy. Animal implantation of OPLA implants was...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-200209000-00005
更新日期:2002-09-01 00:00:00
abstract::A 64-year-old woman presented with periorbital induration of 6 months' duration. Computed tomography (CT) revealed enlargement of extraocular muscles. A biopsy specimen of the orbicularis muscle and indurated preaponeurotic fat demonstrated an infiltrating carcinoma, and immunoperoxidase studies for surface antigens s...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-199112000-00003
更新日期:1991-01-01 00:00:00
abstract::A 21-year-old US soldier received a penetrating eye injury while fighting in Iraq and was treated with evisceration. Sympathetic ophthalmia developed, which responded well to steroid treatment. This is the first case of sympathetic ophthalmia after a war injury reported since World War II. ...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/01.iop.0000203495.67894.c7
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:The Golden ratio, or Phi, has been used to explain the substrates of two-dimensional beauty utilizing the faces of models. A "Phi point" has been identified at the apex of the cheek mound that can be targeted in filler injections. The authors report herein how they have applied this algorithm for surgical shapi...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0000000000001167
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:To assess the effect of upper eyelid blepharoplasty surgery on contrast sensitivity. METHODS:A prospective study was performed. Pre- and postoperative contrast sensitivity measurements were taken on patients undergoing routine upper eyelid blepharoplasty surgery. The patients were selected for surgery on the b...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e31823d2125
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:To examine the relationship of horizontal lower eyelid laxity, frequency of involutional entropion occurrence, and age of Asian patients. METHODS:Three hundred seventy-six Japanese patients were examined (age range, 3-95 years). The horizontal laxity was examined with a pinch test. A pinch test of >8 mm was ju...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e3182a64f88
更新日期:2013-11-01 00:00:00
abstract::A 50-year-old male presented with bilateral cicatricial entropion with subepithelial fibrosis and fornix foreshortening. Conjunctival biopsy showed lymphocytic infiltrate along the interface of the epithelium and lamina propria with linear, shaggy fibrinogen deposition along the epithelial basement membrane zone, supp...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0000000000000933
更新日期:2017-11-01 00:00:00
abstract::We present the results of a pilot study of the use of Nd:Yag laser in the removal of permanent eyeliner tattoos. Fourteen eyelids were treated, and in all cases a reduction in pigmentation was achieved although responses were variable. The advantages of such therapy over existing techniques are described. The techniqu...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-199212000-00010
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:An experimental study to demonstrate in animal eyelids that the controlled exposure of excised tarsal plate to ultraviolet-A radiation can induce a rigidification effect due to photochemical crosslinking of the constitutive collagen. METHODS:Excised strips of sheep tarsus were irradiated with ultraviolet-A ray...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0000000000001063
更新日期:2018-09-01 00:00:00
abstract::A 60-year-old woman under treatment for a left lower eyelid abscess developed a right caruncle abscess. Methicillin-resistant Staphylococcus aureus (MRSA) was identified in cultures performed on both lesions. Treatment consisted of oral ciprofloxacin and moxifloxacin drops. There was resolution of both lesions with in...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e3180300700
更新日期:2007-03-01 00:00:00
abstract::The repair of severe upper eyelid entropion with trichiasis was reported early in ophthalmological literature; a historical review of the main operative techniques is provided. The aim of treatment is to bring the eyelashes away from the lid margin. Recent procedures use an upward transposition of the anterior lamella...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::Primary localized lacrimal gland amyloidosis is an extremely rare occurrence. The typical clinical and radiologic appearances have been suggested but not clearly established. This report describes two patients with amyloid tumor of the lacrimal gland. Both patients were middle-aged women of Asian origin, one a Chinese...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/01.iop.0000222354.44000.eb
更新日期:2006-07-01 00:00:00
abstract:PURPOSE:To compare the success rate of monocanalicular versus bicanalicular silicone intubation of incomplete nasolacrimal duct obstruction (nasolacrimal duct stenosis) in adults. METHODS:In a retrospective, nonrandomized comparative case series, 48 eyes of 44 adult patients with nasolacrimal duct stenosis underwent e...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/01.iop.0000155524.04390.7b
更新日期:2005-03-01 00:00:00
abstract::Orbital intraosseous hemangiomas are rare entities, with only 15 previously reported. We review these and present our own. They are benign, vascular tumors, typically found in the frontal, ethmoid, or zygomatic bones. They tend to present in the 4th or 5th decades as a mildly painful orbital rim mass. Ocular findings ...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章,评审
doi:10.1097/00002341-198912000-00004
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:To report three patients with sinonasal undifferentiated carcinoma (SNUC) that invaded the orbit. METHODS:Retrospective small case series. The clinical, radiographic, and pathologic features of three patients with SNUC were reviewed. RESULTS:Three patients with SNUC that invaded the orbit were evaluated. A bi...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-200107000-00009
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:Essential blepharospasm can be associated with apraxia of eyelid opening and is characterized by the inability to initiate the act of eyelid elevation even after cessation of orbicularis spasms. Current therapies such as botulinum toxin injections, orbicularis resection, or neurectomy may be unsuccessful or hav...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-200001000-00006
更新日期:2000-01-01 00:00:00
abstract:PURPOSE:Aimed to evaluate normal volume of the lacrimal gland in patients of different age groups and race. METHODS:All MRI studies of the brain that were done between June 2012 and April 2013 were examined. Lacrimal glands were identified using fat-saturated fluid-attenuated inversion recovery (FLAIR) images, and the...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0000000000000117
更新日期:2014-09-01 00:00:00
abstract::Medical photographic documentation is important for professional, research, and ethical concerns. This study analyzed the possible interference that the flash could cause on evaluation of lower eyelid cosmetic results. Standardized photographs with and without flash were taken of 10 patients with dermatochalasis. The ...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e31821b6daf
更新日期:2012-03-01 00:00:00
abstract::Seven patients with significant frontal trauma involving the supraorbital region associated with orbital roof "blow-in" fractures were admitted to the Maryland Institute for Emergency Medical Services Systems (MIEMSS) at the University of Maryland Medical System over a 16-month period. High-resolution computed tomogra...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-199106000-00001
更新日期:1991-01-01 00:00:00
abstract:PURPOSE:To evaluate the effectiveness of oxymetazoline combined with lidocaine versus cocaine for outpatient dacryocystorhinostomy (DCR). METHODS:Twenty-seven patients underwent DCR with a combination of oxymetazoline 0.05% nasal spray and lidocaine 4% spray/pledgetts (oxy/lido) and were compared with 28 patients who ...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-200005000-00006
更新日期:2000-05-01 00:00:00
abstract:PURPOSE:To determine and compare the amount of force required to disrupt the integrity of various orbital implants. METHODS:Compression tests were carried out by using a servo-electrical universal testing system on orbital implants including aluminum oxide (Bioceramic implant, FCI, Issy-Les-Moulineaux, France), corall...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/01.iop.0000162959.30970.0d
更新日期:2005-05-01 00:00:00
abstract::Ocular dystopia with inferomedial displacement of the globe is an unusual but well-recognized complication of bony orbital decompression. It is caused by displacement of the muscle cone and orbital connective tissue system into the maxillary and ethmoidal sinuses. We illustrate a surgical variation of bony orbital dec...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-199203000-00005
更新日期:1992-01-01 00:00:00
abstract::A 14-year-old boy was referred with complaints of decreased vision, pain, and diplopia that developed in his right eye after trauma. Radiologic studies showed an orbital roof fracture with an associated subperiosteal hematoma. Orbital exploration with surgical drainage of the hematoma and roof fracture repair was perf...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-199805000-00008
更新日期:1998-05-01 00:00:00
abstract:PURPOSE:To compare the results of 2 methods of upper eyelid sling placement with autogenous fascia lata in the treatment of congenital ptosis. METHODS:In a randomized clinical trial, patients with congenital upper eyelid ptosis and poor levator function (<4 mm) were randomly assigned to either of 2 methods of upper ey...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章,随机对照试验
doi:10.1097/IOP.0b013e3180557479
更新日期:2007-05-01 00:00:00
abstract::To investigate causes, associations, and results of treatment with blepharospasm, 1,653 patients were evaluated by extensive questionnaires to study blepharospasm and long-term results of treatment with the full myectomy operation, botulinum-A toxin, drug therapy, and help from the Benign Essential Blepharospasm Resea...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 历史文章,杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::A meningoencephalocele is a herniation of meninges and brain out of the cranial fossa through a bony defect. Cerebrospinal fluid leakage may occur due to a defect in the wall of the meningoencephalocele. The defect may be traumatic, iatrogenic, or may appear spontaneously. In this report, the authors present an unreco...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e3181710962
更新日期:2008-05-01 00:00:00
abstract::A 26-year-old man presented with symptoms suggesting idiopathic orbital inflammatory disease. After a poor initial response to oral steroids, an orbital biopsy confirmed the diagnosis. A paucicellular lymphocytic infiltrate with areas of fibrosis was seen to replace normal tissue. With the development of exposure kera...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/01.iop.0000231549.24125.7a
更新日期:2006-09-01 00:00:00
abstract::An 89-year-old woman presented after blunt injury to the left orbit from a fall. Examination findings were suggestive of left-sided orbital compartment syndrome, unresponsive to emergent lateral canthotomy and cantholysis. CT revealed a left-sided orbital floor blowout fracture involving the infraorbital canal, with a...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0000000000000828
更新日期:2017-09-01 00:00:00
abstract::We report a case of a man who had undergone gold eyelid loading for lagophthalmos 22 years earlier. During examination for a complaint of foreign body sensation in the operated eye, the gold weight was found under the palpebral conjunctiva. Although extrusion of a gold weight through the skin anteriorly is well recogn...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/01.IOP.0000087032.75134.77
更新日期:2003-09-01 00:00:00
abstract:PURPOSE:Platinum chains are thinner than gold weights (GWs) and may confer a better eyelid curvature profile with reduced visibility. Outcomes compared eyelid measurements, cosmesis, and complications. METHODS:Forty-two primary GW and 17 primary platinum chain insertions were identified and subsequently matched for la...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章,随机对照试验
doi:10.1097/IOP.0b013e3182467bf7
更新日期:2012-05-01 00:00:00