Neonatal critical illness and development: white matter and hippocampus alterations in school-age neonatal extracorporeal membrane oxygenation survivors.

Abstract:

AIM:To examine the neurobiology of long-term neuropsychological deficits after neonatal extracorporeal membrane oxygenation (ECMO). METHOD:This cross-sectional study assessed white matter integrity and hippocampal volume of ECMO survivors (8-15y) and healthy children (8-17y) using diffusion tensor imaging (DTI) and structural magnetic resonance imaging (MRI) respectively. Neuropsychological outcome was evaluated in ECMO survivors. Included clinical predictors of white matter integrity: age start ECMO, ECMO duration, highest oxygenation index before ECMO, highest mean airway pressure, and mechanical ventilation duration. RESULTS:ECMO survivors (n=23) had lower global fractional anisotropy than healthy children (n=54) (patients=0.368; comparison group=0.381; p=0.018), but similar global mean diffusivity (p=0.410). ECMO survivors had lower fractional anisotropy in the left cingulum bundle (ECMO survivors=0.345; comparison group=0.399; p<0.001) and higher mean diffusivity in a region of the left parahippocampal cingulum (patients=0.916; comparison group=0.871; p<0.001). Higher global mean diffusivity predicted worse verbal memory in ECMO survivors (n=17) (β=-0.74, p=0.008). ECMO survivors (n=23) had smaller bilateral hippocampal volume than healthy children (n=43) (left, p<0.001; right, p<0.001) and this was related to worse verbal memory (left, β=0.65, p=0.018; right, β=0.71, p=0.006). INTERPRETATION:Neonatal ECMO survivors are at risk for long-term brain alterations, which may partly explain long-term neuropsychological impairments. Neuroimaging may contribute to better risk stratification of long-term impairments.

journal_name

Dev Med Child Neurol

authors

Schiller RM,van den Bosch GE,Muetzel RL,Smits M,Dudink J,Tibboel D,Ijsselstijn H,White T

doi

10.1111/dmcn.13309

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

304-310

issue

3

eissn

0012-1622

issn

1469-8749

journal_volume

59

pub_type

杂志文章
  • Feeding ability in Rett syndrome.

    abstract::Feeding abilities in 20 individuals with Rett syndrome aged 1 1/2 to 33 years were investigated by history and clinical assessment during a meal, followed by videofluoroscopy of feeding. All were shown to have reduced movements of the mid and posterior tongue, with premature spillover of food and liquid from the mouth...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1997.tb07440.x

    authors: Morton RE,Bonas R,Minford J,Kerr A,Ellis RE

    更新日期:1997-05-01 00:00:00

  • Power mobility skill progression for children and adolescents: a systematic review of measures and their clinical application.

    abstract:AIM:To identify and critically appraise standardized measures of power mobility skill used with children (18y or younger) with mobility limitations and explore the measures' application for 'exploratory', 'operational', and 'functional' learners. METHOD:Five electronic databases were searched along with hand-searching...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章,评审

    doi:10.1111/dmcn.13709

    authors: Field DA,Livingstone RW

    更新日期:2018-10-01 00:00:00

  • Botulinum toxin as an adjunct to motor learning therapy and surgery for obstetrical brachial plexus injury.

    abstract::Following obstetrical brachial plexus injury, infants are unable to learn specific patterns of movement due to the disruption of neural pathways. Even with successful reinnervation (spontaneously or post surgical reconstruction), function can be suboptimal due to overactivity in antagonist muscles preventing movement ...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1017/S0012162206000557

    authors: DeMatteo C,Bain JR,Galea V,Gjertsen D

    更新日期:2006-04-01 00:00:00

  • One-Minute Walk and modified Timed Up and Go tests in children with cerebral palsy: performance and minimum clinically important differences.

    abstract::AIM This prospective multicenter study assessed performance and changes over time, with and without surgical intervention, in the modified Timed Up and Go (mTUG) and One-Minute Walk tests (1MWT) in children with bilateral cerebral palsy (CP). Minimum clinically important differences (MCIDs) were established for these ...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/dmcn.12325

    authors: Hassani S,Krzak JJ,Johnson B,Flanagan A,Gorton G 3rd,Bagley A,Ounpuu S,Romness M,Tylkowski C,Oeffinger D

    更新日期:2014-05-01 00:00:00

  • Wearable wrist activity monitor as an indicator of functional hand use in children with cerebral palsy.

    abstract:AIM:New tools that capture hand function in everyday activities and contexts are needed for assessing children with hemiplegic cerebral palsy. This study evaluates a wearable wrist monitor and tests the hypothesis that wrist extension frequency (FreqE) is an appropriate indicator of functional hand use. METHOD:Fifteen...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.2011.04078.x

    authors: Howcroft J,Fehlings D,Zabjek K,Fay L,Liang J,Biddiss E

    更新日期:2011-11-01 00:00:00

  • Childhood nocturnal enuresis: factors associated with outcome of treatment with an enuresis alarm.

    abstract::A study was carried out to assess the factors that may affect the outcome of a single course of treatment for childhood nocturnal enuresis by use of an enuresis alarm. 113 children were treated and followed up; those showing failure of initial arrest of wetting, relapse and longterm successful outcome were analysed se...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1983.tb13723.x

    authors: Dische S,Yule W,Corbett J,Hand D

    更新日期:1983-02-01 00:00:00

  • Comparison of reflex modification procedures and auditory brainstem response in high-risk neonates.

    abstract::This study compared the results of reflex modification (RM)--an objective technique for assessing brainstem sensorineural processing--with those of auditory brainstem response (ABR) for a group of high-risk infants at comparable postconceptional ages. For the RM procedure, an eyeblink-eliciting tap to the glabella was...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1991.tb05091.x

    authors: Anday EK,Cohen ME,Hoffman HS

    更新日期:1991-02-01 00:00:00

  • Acquired aphasia in children after surgical resection of left-thalamic tumors.

    abstract::Five children (three males, two females; four right-, one left-handed; age range 6 to 14 years) who developed aphasia after gross-total excision of left predominantly thalamic tumors are reported. Three patients had Broca aphasia, one had mixed transcortical aphasia, and one patient had conduction aphasia. In the mont...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1017/s0012162200001109

    authors: Nass R,Boyce L,Leventhal F,Levine B,Allen J,Maxfield C,Salsberg D,Sarno M,George A

    更新日期:2000-09-01 00:00:00

  • The reliability and validity of a research-grade pedometer for children and adolescents with cerebral palsy.

    abstract:AIM:The aim of this study was to determine the reliability, validity, and optimal placement of pedometers in children with cerebral palsy (CP) who ambulate without aids. METHOD:Seventeen participants aged 7 to 17 years with CP (eight males, nine females; mean age 12y 4mo; SD 3y 2mo), who could ambulate without aids, w...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/dmcn.12181

    authors: Maher C,Kenyon A,McEvoy M,Sprod J

    更新日期:2013-09-01 00:00:00

  • Visually impaired children and haptic intelligence test scores: intelligence test for visually impaired children (ITVIC).

    abstract::This paper reports the results of verbal and haptic intelligence tests for the whole population of the visually impaired, braille-educated Dutch children and Dutch-speaking children in Belgium. The scores of children with and without usable vision generally confirmed expectations. Children with usable vision had highe...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1993.tb11678.x

    authors: Dekker R

    更新日期:1993-06-01 00:00:00

  • Peripheral neuropathy in Leigh's encephalomyelopathy.

    abstract::An infant with subacute necrotising encephalopathy is described, in whom slow motornerve conduction velocities suggested the presence of peripheral neuropathy. Peripheral nerves are not invariably involved in patients with this disease, but as they are involved in thiamine-deficiency states it is conjectured that the ...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1975.tb03529.x

    authors: Moosa A

    更新日期:1975-10-01 00:00:00

  • Goldenhar syndrome and autistic behaviour.

    abstract::Two girls with concomitant Goldenhar syndrome (oculo-auriculovertebral spectrum disorder) and autistic disorder are described. One was diagnosed as having Goldenhar syndrome in the first few weeks of life and as having autistic disorder in her fifth year; the other was diagnosed as having Goldenhar syndrome when she w...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1992.tb11405.x

    authors: Landgren M,Gillberg C,Strömland K

    更新日期:1992-11-01 00:00:00

  • Abnormalities in the coordination of respiration and swallow in preterm infants with bronchopulmonary dysplasia.

    abstract::Individual rhythms of suck, swallow, and respiration are disrupted in preterm infants with bronchopulmonary dysplasia (BPD). Integration of respiration into suck-swallow efforts is critical for establishing coordinated suckle feeding. This study quantitatively assessed the coordination of respiration and swallow in in...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1017/S0012162206001241

    authors: Gewolb IH,Vice FL

    更新日期:2006-07-01 00:00:00

  • The epidemiology of spina bifida in south-western Ohio--1970-1979.

    abstract::Multiple epidemiological variables of 131 children with spina bifida born during 1970 and 1979 in a seven-county urban/rural region of south-western Ohio were analyzed retrospectively via personal interviews, hospital and clinic records, and birth and stillbirth certificates. The estimated incidence of spina bifida wa...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1985.tb03767.x

    authors: Crowe CA,Heuther CA,Oppenheimer SG,Barth LD,Jeffrey E,Reinhart S

    更新日期:1985-04-01 00:00:00

  • Helicobacter pylori in an institution for disabled children in Hong Kong.

    abstract::Anti-Helicobacter pylori antibodies were determined in 157 institutionalised Cantonese children, mean age 9.5 +/- 3.9 (SD) years, with profound neurodevelopmental disabilities. Eighty-seven (55.4%) were H. pylori seropositive compared with four of 50 (8%, P > 0.0002) of an age-matched control group, mean age 7.2 +/- 4...

    journal_title:Developmental medicine and child neurology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1469-8749.1997.tb07363.x

    authors: Lewindon PJ,Lau D,Chan A,Tse P,Sullivan PB

    更新日期:1997-10-01 00:00:00

  • A new motor performance test in a prospective study on children with suspected myopathy.

    abstract::In the development of a new diagnostic motor performance test to spare more children from painful muscle biopsy, seven functional items were used to measure muscle strength and muscle endurance in a prospective study on new patients. Over a 2-year period, 22 patients (12 males, 10 females; mean age 8y 1mo [SD 2y 6mo],...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1017/S0012162206001587

    authors: van den Beld WA,van der Sanden GA,Feuth T,Janssen AJ,Sengers RC,Verbeek AL,Gabreëls FJ

    更新日期:2006-09-01 00:00:00

  • Assessing the impact of a child with spina bifida on the family.

    abstract::This study examined the characteristics of families which may be more vulnerable than others to the impact of caring for a child with spina bifida. Morbidity and the use of health services were unexpectedly high. The impact on the family was related less to clinical diagnoses than to the characteristics of the child's...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1986.tb03831.x

    authors: McCormick MC,Charney EB,Stemmler MM

    更新日期:1986-02-01 00:00:00

  • Melatonin treatment for sleep disorders in children with neurodevelopmental disorders: an observational study.

    abstract::The study aim was to quantify melatonin-associated improvement in sleep by means of a parent-completed sleep diary during routine outpatient activity. An investigation into sleep disturbance was made at neurology outpatient appointments. Those parents who identified a problem were asked to complete a sleep diary, afte...

    journal_title:Developmental medicine and child neurology

    pub_type: 临床试验,杂志文章

    doi:10.1017/s0012162201002171

    authors: Ross C,Davies P,Whitehouse W

    更新日期:2002-05-01 00:00:00

  • Exercise interventions improve postural control in children with cerebral palsy: a systematic review.

    abstract:AIM:The aim of this study was to evaluate the efficacy and effectiveness of exercise interventions that may improve postural control in children with cerebral palsy (CP). METHOD:A systematic review was performed using American Academy of Cerebral Palsy and Developmental Medicine (AACPDM) and Preferred Reporting Items ...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章,评审

    doi:10.1111/dmcn.12660

    authors: Dewar R,Love S,Johnston LM

    更新日期:2015-06-01 00:00:00

  • Somatosensory testing in idiopathic scoliosis.

    abstract::Sixty-seven consecutive patients (59 females, eight males; mean age 13.6 years, age range 8.1 to 18 years) with adolescent idiopathic scoliosis were evaluated for segmental dystonia, thermal and vibratory thresholds, and cortical somatosensory evoked potentials (cSEPs). Clinically, there were no signs of segmental dys...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:

    authors: Olafsson Y,Odergren T,Persson HE,Saraste H

    更新日期:2002-02-01 00:00:00

  • EEGs in phenylketonuria. I: Follow-up to adulthood; II: Short-term diet-related changes in EEGs and cognitive function.

    abstract::The authors report the results of two EEG studies on adult patients with phenylketonuria (PKU) who had been treated early. Part I: the authors followed the EEGs of 34 PKU patients from birth to age 21. The frequency of abnormal EEG findings (especially epileptiform activity) steadily increased until age 12, then decre...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1993.tb11552.x

    authors: Pietz J,Schmidt E,Matthis P,Kobialka B,Kutscha A,de Sonneville L

    更新日期:1993-01-01 00:00:00

  • Decreased fracture incidence after 1 year of pamidronate treatment in children with spastic quadriplegic cerebral palsy.

    abstract:AIM:The aim of this study was to assess the rate of fracture before and after a 1-year course of intravenous pamidronate in children with spastic quadriplegic cerebral palsy (CP) who had previously experienced fractures. METHOD:Twenty-five children (nine males, 16 females) with quadriplegic CP in Gross Motor Function ...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.2010.03676.x

    authors: Bachrach SJ,Kecskemethy HH,Harcke HT,Hossain J

    更新日期:2010-09-01 00:00:00

  • Longitudinal study of growth and development of young Jamaican children recovering from severe protein-energy malnutrition.

    abstract::The developmental level and nutritional status of a group of 17 children aged between six and 24 months who were admitted to hospital with severe protein-energy malnutrition were studied from admission to hospital until 36 months after returning home. They were compared with a group of 14 adequately nourished children...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1982.tb13624.x

    authors: Grantham-McGregor SM,Powell C,Stewart M,Schofield WN

    更新日期:1982-06-01 00:00:00

  • Early magnetic resonance imaging to detect presymptomatic leptomeningeal angioma in children with suspected Sturge-Weber syndrome.

    abstract:AIM:We aimed to evaluate the contribution of early magnetic resonance imaging (MRI) for the presymptomatic diagnosis of Sturge-Weber syndrome (SWS) in infants with a facial port-wine birthmark (PWB). METHOD:Asymptomatic infants with a facial PWB who performed a first MRI scan before 3 months and a second MRI scan afte...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/dmcn.14253

    authors: Bar C,Pedespan JM,Boccara O,Garcelon N,Levy R,Grévent D,Boddaert N,Nabbout R

    更新日期:2020-02-01 00:00:00

  • A dyspraxic deficit in specific language impairment and developmental coordination disorder? Evidence from hand and arm movements.

    abstract::The extent to which children with either specific language impairment (SLI) or developmental coordination disorder (DCD) could be considered dyspraxic was examined using three tasks involving either familiar, or unfamiliar actions. SLI is diagnosed in children who fail to develop language in the normal fashion for no ...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1998.tb08214.x

    authors: Hill EL

    更新日期:1998-06-01 00:00:00

  • Obstetric history and the heart-rate response of newborns to sound.

    abstract::Two groups of clinically normal newborns, differing in the number of non-optimal factors in their obstetric history, were compared by measuring heart-rate response to a series of auditory stimuli. There was a significant difference between the groups in the direction of the average heart-rate response. The high risk" ...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1976.tb03685.x

    authors: Kittner S,Lipsitt LP

    更新日期:1976-08-01 00:00:00

  • Development and psychometric properties of the Hand-Use-at-Home questionnaire to assess amount of affected hand-use in children with unilateral paresis.

    abstract:AIM:To describe the development of the parent-rated Hand-Use-at-Home questionnaire (HUH) assessing the amount of spontaneous use of the affected hand in children with unilateral paresis, and to test its internal structure, unidimensionality, and validity. METHOD:Parents of children with unilateral cerebral palsy (CP) ...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/dmcn.13449

    authors: Geerdink Y,Aarts P,van der Holst M,Lindeboom R,Van Der Burg J,Steenbergen B,Geurts AC

    更新日期:2017-09-01 00:00:00

  • Verbal and memory skills in males with Duchenne muscular dystrophy.

    abstract::Duchenne muscular dystrophy (DMD) is a progressive pediatric disorder that affects both muscle and brain. Children with DMD have mean IQ scores that are about one standard deviation lower than population means, with lower Verbal IQ than Performance IQ scores. For the present study, verbal skills and verbal memory skil...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.2007.00123.x

    authors: Hinton VJ,Fee RJ,Goldstein EM,De Vivo DC

    更新日期:2007-02-01 00:00:00

  • Herpes simplex virus-induced anti-N-methyl-d-aspartate receptor encephalitis: a systematic literature review with analysis of 43 cases.

    abstract:AIM:To conduct a systematic literature review on patients with biphasic disease with herpes simplex virus (HSV) encephalitis followed by anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis. METHOD:We conducted a case report and systematic literature review (up to 10 December 2016), focused on differences between h...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章,评审

    doi:10.1111/dmcn.13448

    authors: Nosadini M,Mohammad SS,Corazza F,Ruga EM,Kothur K,Perilongo G,Frigo AC,Toldo I,Dale RC,Sartori S

    更新日期:2017-08-01 00:00:00

  • Epidemiology of headache and childhood migraine in an urban general practice using Ad Hoc, Vahlquist and IHS criteria.

    abstract::In a survey conducted by a UK urban general practice, 98.1 per cent (1083) of the children registered aged three to 11 years took part in an interview. Possible migraine subjects took part in an extended interview, the results of which were recorded using three different sets of diagnostic criteria: Vahlquist, Ad Hoc ...

    journal_title:Developmental medicine and child neurology

    pub_type: 杂志文章

    doi:10.1111/j.1469-8749.1992.tb11423.x

    authors: Mortimer MJ,Kay J,Jaron A

    更新日期:1992-12-01 00:00:00