Mapping the Information Trace in Local Field Potentials by a Computational Method of Two-Dimensional Time-Shifting Synchronization Likelihood Based on Graphic Processing Unit Acceleration.

Abstract:

:The local field potential (LFP) is a signal reflecting the electrical activity of neurons surrounding the electrode tip. Synchronization between LFP signals provides important details about how neural networks are organized. Synchronization between two distant brain regions is hard to detect using linear synchronization algorithms like correlation and coherence. Synchronization likelihood (SL) is a non-linear synchronization-detecting algorithm widely used in studies of neural signals from two distant brain areas. One drawback of non-linear algorithms is the heavy computational burden. In the present study, we proposed a graphic processing unit (GPU)-accelerated implementation of an SL algorithm with optional 2-dimensional time-shifting. We tested the algorithm with both artificial data and raw LFP data. The results showed that this method revealed detailed information from original data with the synchronization values of two temporal axes, delay time and onset time, and thus can be used to reconstruct the temporal structure of a neural network. Our results suggest that this GPU-accelerated method can be extended to other algorithms for processing time-series signals (like EEG and fMRI) using similar recording techniques.

journal_name

Neurosci Bull

journal_title

Neuroscience bulletin

authors

Zhao ZF,Li XZ,Wan Y

doi

10.1007/s12264-017-0175-5

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

653-663

issue

6

eissn

1673-7067

issn

1995-8218

pii

10.1007/s12264-017-0175-5

journal_volume

33

pub_type

杂志文章
  • Morphological and behavioral consequences of recurrent seizures in neonatal rats are associated with glucocorticoid levels.

    abstract:OBJECTIVE:It is well documented that epilepsy can increase neurogenesis in certain brain regions and cause behavioral alternations in patients and different epileptic animal models. A series of experimental studies have demonstrated that neurogenesis is regulated by various factors including glucocorticoid (CORT), whic...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-007-0012-3

    authors: Shi XY,Wang JW,Lei GF,Sun RP

    更新日期:2007-03-01 00:00:00

  • The Orphan Nuclear Receptor TLX/NR2E1 in Neural Stem Cells and Diseases.

    abstract::The human TLX gene encodes an orphan nuclear receptor predominantly expressed in the central nervous system. Tailess and Tlx, the TLX homologues in Drosophila and mouse, play essential roles in body-pattern formation and neurogenesis during early embryogenesis and perform crucial functions in maintaining stemness and ...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章,评审

    doi:10.1007/s12264-015-0004-7

    authors: Wang T,Xiong JQ

    更新日期:2016-02-01 00:00:00

  • Uric formaldehyde levels are negatively correlated with cognitive abilities in healthy older adults.

    abstract::Recent studies have shown that the abnormal accumulation of endogenous formaldehyde could be a critical factor in age-related cognitive decline. The aim of this study was to estimate the correlation between uric formaldehyde and general cognitive abilities in a community-based elderly population, and to measure the ex...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-013-1416-x

    authors: Yu J,Su T,Zhou T,He Y,Lu J,Li J,He R

    更新日期:2014-04-01 00:00:00

  • Chronic Intracerebroventricular Infusion of Metformin Inhibits Salt-Sensitive Hypertension via Attenuation of Oxidative Stress and Neurohormonal Excitation in Rat Paraventricular Nucleus.

    abstract::Metformin (MET), an antidiabetic agent, also has antioxidative effects in metabolic-related hypertension. This study was designed to determine whether MET has anti-hypertensive effects in salt-sensitive hypertensive rats by inhibiting oxidative stress in the hypothalamic paraventricular nucleus (PVN). Salt-sensitive r...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-018-0308-5

    authors: Yu XJ,Zhao YN,Hou YK,Li HB,Xia WJ,Gao HL,Liu KL,Su Q,Yang HY,Liang B,Chen WS,Cui W,Li Y,Zhu GQ,Yang ZM,Kang YM

    更新日期:2019-02-01 00:00:00

  • Assessing the Accuracy of the Modified Chinese Autism Spectrum Rating Scale and Social Responsiveness Scale for Screening Autism Spectrum Disorder in Chinese Children.

    abstract::The reported prevalence of autism spectrum disorder (ASD) has been increasing rapidly in many parts of the world. However, data on its prevalence in China are largely missing. Here, we assessed the suitability of the modified Chinese version of a newly-developed ASD screening tool, the Modified Chinese Autism Spectrum...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-017-0114-5

    authors: Zhou B,Zhou H,Wu L,Zou X,Luo X,Fombonne E,Wang Y,Yan W,Xu X

    更新日期:2017-04-01 00:00:00

  • BDNF Overexpression Enhances the Preconditioning Effect of Brief Episodes of Hypoxia, Promoting Survival of GABAergic Neurons.

    abstract::Hypoxia causes depression of synaptic plasticity, hyperexcitation of neuronal networks, and the death of specific populations of neurons. However, brief episodes of hypoxia can promote the adaptation of cells. Hypoxic preconditioning is well manifested in glutamatergic neurons, while this adaptive mechanism is virtual...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-020-00480-z

    authors: Turovskaya MV,Gaidin SG,Vedunova MV,Babaev AA,Turovsky EA

    更新日期:2020-07-01 00:00:00

  • Olfactory Dysfunction as an Early Biomarker in Parkinson's Disease.

    abstract::Olfactory dysfunction is common in Parkinson's disease (PD) and often predates the diagnosis by years, reflecting early deposition of Lewy pathology, the histologic hallmark of PD, in the olfactory bulb. Clinical tests are available that allow for the rapid characterization of olfactory dysfunction, including tests of...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章,评审

    doi:10.1007/s12264-017-0170-x

    authors: Fullard ME,Morley JF,Duda JE

    更新日期:2017-10-01 00:00:00

  • Roles of TRESK, a novel two-pore domain K+ channel, in pain pathway and general anesthesia.

    abstract::TRESK is the most recently reported two-pore domain K+ channel, and different from other two-pore domain channels in gene, molecular structure, electrophysiological and pharmacological properties. Although the current knowledge of this potassium channel is inadequate, researches have demonstrated that TRESK is remarka...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章,评审

    doi:10.1007/s12264-008-0225-0

    authors: Huang DY,Yu BW,Fan QW

    更新日期:2008-06-01 00:00:00

  • Cortical Organization of Centrifugal Afferents to the Olfactory Bulb: Mono- and Trans-synaptic Tracing with Recombinant Neurotropic Viral Tracers.

    abstract::Sensory processing is strongly modulated by different brain and behavioral states, and this is based on the top-down modulation. In the olfactory system, local neural circuits in the olfactory bulb (OB) are innervated by centrifugal afferents in order to regulate the processing of olfactory information in the OB under...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-019-00385-6

    authors: Wen P,Rao X,Xu L,Zhang Z,Jia F,He X,Xu F

    更新日期:2019-08-01 00:00:00

  • Construction and functional activity of a recombinant vector expressing rat glutamic acid decarboxylase 65.

    abstract:OBJECTIVE:Glutamic acid decarboxylase 2 (GAD65) is a gamma-aminobutyric acid (GABA) synthetase. This study aimed to construct a recombinant lentivirus-rGAD65 (rLV-rGAD65) vector containing the cDNA of rat GAD65 (rGAD65) and assess its functional activity in vitro and in vivo. METHODS:cDNA of rGAD65 was amplified by RT...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-011-1840-8

    authors: Liu JS,Wang Q,Zhang JB,Kong LJ,Yao SY,Zheng DY,Xu QY

    更新日期:2011-12-01 00:00:00

  • Identification of autophagy signaling network that contributes to stroke in the ischemic rodent brain via gene expression.

    abstract::Autophagy plays a vital role in cerebral ischemia and may be a potential target for developing novel therapy for stroke. In this study, we constructed an autophagy-related pathway network by analyzing the genes related to autophagy and ischemic stroke, and the risk genes were screened. Two autophagy-related modules we...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-015-1547-3

    authors: Liang K,Zhu L,Tan J,Shi W,He Q,Yu B

    更新日期:2015-08-01 00:00:00

  • Sexual dimorphism of the electrophysiological properties of the projection neurons in the robust nucleus of the arcopallium in adult zebra finches.

    abstract:OBJECTIVE:To observe the sexual differences in electrophysiological properties of neurons in the robust nucleus of the arcopallium (RA) in adult zebra finches, and to provide the direct electrophysiological evidence for the sexual dimorphism of birdsong. METHODS:Whole-cell recording was used to record the spontaneous ...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-010-1010-4

    authors: Liu XL,Hou GQ,Liao SQ,Li DF

    更新日期:2010-04-01 00:00:00

  • Clinical Application of Chromosome Microarray Analysis in Han Chinese Children with Neurodevelopmental Disorders.

    abstract::Chromosome microarray analysis (CMA) is a cost-effective molecular cytogenetic technique that has been used as a first-line diagnostic test in neurodevelopmental disorders in the USA since 2011. The impact of CMA results on clinical practice in China is not yet well studied, so we aimed to better evaluate this phenome...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-018-0238-2

    authors: Xu M,Ji Y,Zhang T,Jiang X,Fan Y,Geng J,Li F

    更新日期:2018-12-01 00:00:00

  • Exosomes in Parkinson's Disease.

    abstract::Exosomes, nano-sized extracellular vesicles secreted by most cell types, are found in all kinds of biological fluids and tissues, including the central nervous system (CNS). The proposed functions of these vesicles include roles in cell-cell signaling, removal of cellular debris, and transfer of pathogens between cell...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章,评审

    doi:10.1007/s12264-016-0092-z

    authors: Wu X,Zheng T,Zhang B

    更新日期:2017-06-01 00:00:00

  • Loss of VAPB Regulates Autophagy in a Beclin 1-Dependent Manner.

    abstract::Autophagy is an evolutionarily-conserved self-degradative process that maintains cellular homeostasis by eliminating protein aggregates and damaged organelles. Recently, vesicle-associated membrane protein-associated protein B (VAPB), which is associated with the familial form of amyotrophic lateral sclerosis, has bee...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-018-0276-9

    authors: Wu D,Hao Z,Ren H,Wang G

    更新日期:2018-12-01 00:00:00

  • What interests them in the pictures?--differences in eye-tracking between rhesus monkeys and humans.

    abstract::Studies estimating eye movements have demonstrated that non-human primates have fixation patterns similar to humans at the first sight of a picture. In the current study, three sets of pictures containing monkeys, humans or both were presented to rhesus monkeys and humans. The eye movements on these pictures by the tw...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-013-1367-2

    authors: Hu YZ,Jiang HH,Liu CR,Wang JH,Yu CY,Carlson S,Yang SC,Saarinen VM,Rizak JD,Tian XG,Tan H,Chen ZY,Ma YY,Hu XT

    更新日期:2013-10-01 00:00:00

  • Pharmacological kinetics of BmK AS, a sodium channel site 4-specific modulator on Nav1.3.

    abstract:OBJECTIVE:In this study, the pharmacological kinetics of Buthus martensi Karsch (BmK) AS, a specific modulator of voltage-gated sodium channel site 4, was investigated on Na(v)1.3 expressed in Xenopus oocytes. METHODS:Two-electrode voltage clamp was used to record the whole-cell sodium current. RESULTS:The peak curre...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-012-1234-6

    authors: Liu ZR,Tao J,Dong BQ,Ding G,Cheng ZJ,He HQ,Ji YH

    更新日期:2012-06-01 00:00:00

  • P2Y6 receptor and immunoinflammation.

    abstract::The immunocytes microglia in the central nervous system (CNS) were reported to play a crucial role in neurodegeneration. As a member of P2 receptors family, purinoceptor P2Y6 has attracted much attention recently. Previous studies showed that purinoceptor P2Y6 mainly contributed to microglia activation and their later...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章,评审

    doi:10.1007/s12264-009-0120-3

    authors: Liu GD,Ding JQ,Xiao Q,Chen SD

    更新日期:2009-06-01 00:00:00

  • History of pain theories.

    abstract::The concept of pain has remained a topic of long debate since its emergence in ancient times. The initial ideas of pain were formulated in both the East and the West before 1800. Since 1800, due to the development of experimental sciences, different theories of pain have emerged and become central topics of debate. Ho...

    journal_title:Neuroscience bulletin

    pub_type: 历史文章,杂志文章,评审

    doi:10.1007/s12264-011-0139-0

    authors: Chen J

    更新日期:2011-10-01 00:00:00

  • Correlation of free radical level and apoptosis after intracerebral hemorrhage in rats.

    abstract:OBJECTIVE:To investigate the correlation of perihematomal free radical level and neuronal apoptosis following the intracerebral hemorrhage (ICH). METHODS:Animals were randomly divided into 4 groups: sham operation group, model group, 1 mg/kg edaravone group, and 3 mg/kg edaravone group. Each group was then divided int...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-008-0711-4

    authors: Han N,Ding SJ,Wu T,Zhu YL

    更新日期:2008-12-01 00:00:00

  • Awareness is essential for differential delay eyeblink conditioning with soft-tone but not loud-tone conditioned stimuli.

    abstract::The role of awareness in differential delay eyeblink conditioning (DEC) remains controversial. Here, we investigated the involvement of awareness in differential DEC with a soft or a loud tone as the conditioned stimulus (CS). In the experiment, 36 participants were trained in differential DEC with a soft tone (60 dB)...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-013-1400-5

    authors: Huang H,Wu B,Li Q,Yao J,Li X,Yang Y,Wu GY,Sui JF

    更新日期:2014-06-01 00:00:00

  • Properties of tactile responses of neurons in rat thalamic ventroposterolateral nucleus.

    abstract:OBJECTIVE:To determine whether the convergences of tactile information also occur at thalamic ventroposterolateral nucleus in rats, we investigated the properties of tactile responses of the thalamic ventroposterolateral nucleus in rats. METHODS:Unit responses were recorded extracellularly from thalamic ventroposterol...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-007-0045-7

    authors: Bai J,Wang DH,Yin L,An SM,Zhou SC,Cao XH

    更新日期:2007-09-01 00:00:00

  • L-type Calcium Channels are Involved in Iron-induced Neurotoxicity in Primary Cultured Ventral Mesencephalon Neurons of Rats.

    abstract::In the present study, we investigated the mechanisms underlying the mediation of iron transport by L-type Ca2+ channels (LTCCs) in primary cultured ventral mesencephalon (VM) neurons from rats. We found that co-treatment with 100 µmol/L FeSO4 and MPP+ (1-methyl-4-phenylpyridinium) significantly increased the productio...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-019-00424-2

    authors: Xu YY,Wan WP,Zhao S,Ma ZG

    更新日期:2020-02-01 00:00:00

  • Therapeutic Efficacy of Neurostimulation for Depression: Techniques, Current Modalities, and Future Challenges.

    abstract::Depression is the most prevalent debilitating mental illness; it is characterized as a disorder of mood, cognitive function, and neurovegetative function. About one in ten individuals experience depression at some stage of their lives. Antidepressant drugs are used to reduce the symptoms but relapse occurs in ~20% of ...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章,评审

    doi:10.1007/s12264-015-0009-2

    authors: Akhtar H,Bukhari F,Nazir M,Anwar MN,Shahzad A

    更新日期:2016-02-01 00:00:00

  • Epigenetics and neural stem cell commitment.

    abstract::Neural stem cell is presently the research hotspot in neuroscience. Recent progress indicates that epigenetic modulation is closely related to the self-renewal and differentiation of neural stem cell. Epigenetics refer to the study of mitotical/meiotical heritage changes in gene function that cannot be explained by ch...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章,评审

    doi:10.1007/s12264-007-0036-8

    authors: Tang HL,Zhu JH

    更新日期:2007-07-01 00:00:00

  • Optogenetics in neuroscience: what we gain from studies in mammals.

    abstract::Optogenetics is a newly-introduced technology in the life sciences and is gaining increasing attention. It refers to the combination of optical technologies and genetic methods to control the activity of specific cell groups in living tissue, during which high-resolution spatial and temporal manipulation of cells is a...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章,评审

    doi:10.1007/s12264-012-1250-6

    authors: Chen Q,Zeng Z,Hu Z

    更新日期:2012-08-01 00:00:00

  • The selective 5-HT1A receptor antagonist WAY-100635 inhibits neuronal activity of the ventromedial prefrontal cortex in a rodent model of Parkinson's disease.

    abstract:OBJECTIVE:The ventral part of the medial prefrontal cortex (mPFC) plays an important role in initiation and control of voluntary movement, mood and cognition. However, after the degeneration of the nigrostriatal pathway, the neuronal activity of the ventral mPFC and the role of serotonin(1A) (5-hydroxytryptamine, 5-HT(...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-007-0047-5

    authors: Cao J,Liu J,Zhang QJ,Wang T,Wang S,Han LN,Li Q

    更新日期:2007-11-01 00:00:00

  • Modulation of gamma-aminobutyric acid on painful sense in central nervous system of morphine-dependent rats.

    abstract:OBJECTIVE:To observe the effects of gamma-aminobutyric acid (GABA) on the electric activities of pain-excited neurons (PEN) in nucleus accumbens (NAc) in central nervous system (CNS) of morphine-dependent rats. METHODS:After GABA or the GABA(A)-receptor antagonist, bicuculline (Bic), was injected into cerebral ventric...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-008-0227-y

    authors: Xu Y,Xu MY,Li X

    更新日期:2008-10-01 00:00:00

  • Correction to: Recent Advances in the Genetic Dissection of Neural Circuits in Drosophila.

    abstract::In the original publication the fifth line starting with "… with circa 1000, 1000 neurons?" in section Concluding Remarks and Perspectives is incorrectly published. The correct text should read "… with circa 100, 000 neurons?" ...

    journal_title:Neuroscience bulletin

    pub_type: 已发布勘误

    doi:10.1007/s12264-019-00398-1

    authors: Guo C,Pan Y,Gong Z

    更新日期:2019-12-01 00:00:00

  • Stimulus discrimination via responses of retinal ganglion cells and dopamine-dependent modulation.

    abstract::Neighboring retinal ganglion cells (RGCs) fire with a high degree of correlation. It has been increasingly realized that visual perception of the environment relies on neuronal population activity to encode and transmit the information contained in stimuli. Understanding how neuronal population activity contributes to...

    journal_title:Neuroscience bulletin

    pub_type: 杂志文章

    doi:10.1007/s12264-013-1368-1

    authors: Li H,Liang PJ

    更新日期:2013-10-01 00:00:00