Abstract:
:For anatomical restoration of a repaired rotator cuff, mechanical augmentation of the repaired structure is essential. Using histological and biomechanical evaluation in a rat model, the authors sought to determine the efficacy of an absorbable alginate sheet at the supraspinatus tendon-to-bone repair site for healing of the rotator cuff tear. Forty adult (12 weeks old) male Sprague- Dawley wild-type rats were used in this study. The animals were randomly separated into 2 groups: group 1, conventional supraspinatus repair with acute repair; or group 2, supraspinatus repair with absorbable alginate sheet. Biomechanical and histological analyses were performed at 6 and 12 weeks after index rotator cuff surgery. Compared with group 1, group 2 exhibited a significantly greater mean ultimate failure load (group 1, 23.70±3.87 N; group 2, 61.44±43.67 N; P=.023) and mean ultimate stress (group 1, 2.83±0.50 MPa; group 2, 7.36±2.87 MPa; P=.020). However, 6-week outcomes were not significantly different. On histological scoring, compared with group 1, group 2 exhibited a significantly greater mean 6-week score (group 1, 4.10±1.72 points; group 2, 7.80±1.47 points; P<.001) and mean 12-week score (group 1, 3.50±1.00 points; group 2, 5.25±2.62 points; P=.020). Mechanical augmentation with absorbable alginate may improve tendon healing after surgical repair of the rotator cuff. [Orthopedics. 2019; 42(1):e104-e110.].
journal_name
Orthopedicsjournal_title
Orthopedicsauthors
Kim DH,Min SG,Yoon JP,Park GY,Choi JH,Jung JW,Lee HJ,Kim HJ,Chung SW,Kim JYdoi
10.3928/01477447-20181206-04subject
Has Abstractpub_date
2019-01-01 00:00:00pages
e104-e110issue
1eissn
0147-7447issn
1938-2367journal_volume
42pub_type
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