Impact of Obesity on Perioperative Outcomes at Robotic-assisted and Open Radical Prostatectomy: Results From the National Inpatient Sample.

Abstract:

OBJECTIVE:To test the effect of obesity (body mass index ≥30 kg/m2) on perioperative outcomes and total hospital charges at robot-assisted vs open radical prostatectomy (RARP vs ORP). METHODS:Within the National Inpatient Sample database (2008-2015), we identified obese vs nonobese RARP and ORP patients. Estimated annual percent changes, multivariable logistic regression and linear regression models were used. All models were adjusted for clustering and weighted. RESULTS:Of all, 53,626 (60%) underwent RARP vs 35,757 (40%) underwent ORP. At RARP, 8.6% were obese vs 6.9% at ORP. RARP rate increased significantly over time (12.5%-81.5%). Obesity rate increased significantly over time at both, RARP (5.1%-10.5%) and ORP (5.4%-10.7%). In multivariable logistic regression models, obesity predicted 5 of 11 unfavourable perioperative complications at RARP (odds ratio: 1.6-1.8) and 9 of 11 at ORP (odds ratio: 1.3-2.8). In linear regression models, obesity significantly added to total hospital charges at RARP (740$) and ORP (312$). CONCLUSION:Obesity may predispose to higher rates of adverse outcomes at RP. Its effect varies according to surgical approach.

journal_name

Urology

journal_title

Urology

authors

Knipper S,Mazzone E,Mistretta FA,Palumbo C,Tian Z,Briganti A,Saad F,Tilki D,Graefen M,Karakiewicz PI

doi

10.1016/j.urology.2019.05.053

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

135-144

eissn

0090-4295

issn

1527-9995

pii

S0090-4295(19)30646-6

journal_volume

133

pub_type

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