One Cut to Change Them All: CRISPR/Cas, a Groundbreaking Tool for Genome Editing in Botrytis cinerea and Other Fungal Plant Pathogens.

Abstract:

:CRISPR/Cas is a genome editing technology that has opened new dimensions in functional biology. In a recent publication, we presented a highly efficient CRISPR/Cas technique for Botrytis cinerea, which dramatically increases our options to mutagenize and modify single or multiple genes. In this Perspectives article, we describe the essential features of the method and demonstrate with several examples how it opens new avenues for unraveling the virulence mechanisms of Botrytis and other plant pathogenic fungi and can accelerate research for the identification of new antifungal compounds.

journal_name

Phytopathology

journal_title

Phytopathology

authors

Hahn M,Scalliet G

doi

10.1094/PHYTO-09-20-0379-PER

subject

Has Abstract

pub_date

2021-01-29 00:00:00

pages

PHYTO09200379PER

eissn

0031-949X

issn

1943-7684

pub_type

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