Lidocaine and epinephrine levels in tumescent technique liposuction.

Abstract:

:The safety of lidocaine dosing in the tumescent technique has been well documented, but there is little evidence regarding the safety of combining tumescent lidocaine infiltration with subcutaneous lidocaine infiltration required in other aesthetic surgery. The safety of lidocaine and epinephrine dosing was investigated in 10 patients undergoing tumescent technique liposuction alone and in 10 patients undergoing tumescent liposuction with concurrent facial and aesthetic breast surgery by determining serum lidocaine and epinephrine levels at 3, 12, and 23 hours following infiltration of the tumescent solution and the subcutaneous lidocaine. The mean lidocaine dose of all patients was 22.3 mg/kg. All patients demonstrated safe lidocaine levels at all intervals, with the highest levels occurring in patients who received intravenous lidocaine at the induction of anesthesia. The peak epinephrine levels occurred at the 3-hour blood draw and were approximately four times physiologic. No patient demonstrated any subjective or objective signs of lidocaine or epinephrine toxicity.

journal_name

Plast Reconstr Surg

authors

Burk RW 3rd,Guzman-Stein G,Vasconez LO

doi

10.1097/00006534-199606000-00009

subject

Has Abstract

pub_date

1996-06-01 00:00:00

pages

1379-84

issue

7

eissn

0032-1052

issn

1529-4242

journal_volume

97

pub_type

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