Abstract:
OBJECTIVE:To compare all-cause and diabetes-related resource utilization and healthcare charges among adults with type 2 diabetes mellitus who initiated therapy with mealtime insulin disposable pens or vials. METHODS:Data were obtained from the Innovus inVision database from January 1, 2006 through June 30, 2010. Generalized linear models with a gamma distribution and log link estimated the association between medical charges and use of mealtime insulin pens vs vials in the 1 year post-index date, while generalized linear models with a negative binomial distribution estimated resource utilization. RESULTS:Controlling for patient characteristics, general health, and patient copayments, insulin therapy initiation with disposable pens, compared to vials, was associated with significantly fewer all-cause hospitalizations (1.45 vs. 1.66; p < 0.0001) as well as a significantly shorter hospital length of stay (2.16 days vs. 3.53 days; p < 0.0001). Pen use, compared to vials, was also associated with significantly fewer diabetes-related hospitalizations (1.36 vs. 1.47; p < 0.0001), and shorter hospital length of stay (1.12 days vs. 1.72 days; p < 0.0001). Despite higher diabetes-related drug charges ($3593 vs. $2755; p < 0.0001) associated with the use of pens, results showed significantly lower all-cause total healthcare charges ($42,150 vs. $53,340; p < 0.0001) and significantly lower diabetes-related total healthcare charges ($12,722 vs. $14,540; p < 0.0001) for patients who initiated therapy on mealtime insulin with pens compared to vials. LIMITATIONS:Data were drawn from administrative claims and included only patients with medical and outpatient prescription drug benefit coverage. Hence, the results may not be generalizable. The retrospective analyses relied on diagnostic codes to identify patients, assess patient general health, and determine other values, rather than formal, clinical assessments. The analyses did not include indirect healthcare costs. CONCLUSIONS:The administration of mealtime insulin via disposable pens, compared to vials, was associated with a significant reduction in all-cause and diabetes-related resource utilization and total healthcare charges.
journal_name
J Med Econjournal_title
Journal of medical economicsauthors
Eby EL,Boye KS,Lage MJdoi
10.3111/13696998.2013.823091subject
Has Abstractpub_date
2013-10-01 00:00:00pages
1231-7issue
10eissn
1369-6998issn
1941-837Xjournal_volume
16pub_type
杂志文章abstract:INTRODUCTION:SURGIFLO and FLOSEAL are absorbable gelatin-based products that form hemostatic matrices. These products are indicated as adjuncts to hemostasis when control of bleeding by conventional surgical techniques (such as suture, ligature or cautery) is ineffective or impractical. This study analyzed the effect o...
journal_title:Journal of medical economics
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:Journal of medical economics
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abstract:OBJECTIVE:To estimate health-related quality of life (HRQoL) in non-growth hormone deficient (GHD) small for gestational age (SGA) children before and after growth hormone (GH) treatment to adult height (AH). METHODS:This was a multicentre, two-arm trial. Following an initial 2-year double-blind study period, patients...
journal_title:Journal of medical economics
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Journal of medical economics
pub_type: 杂志文章
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journal_title:Journal of medical economics
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journal_title:Journal of medical economics
pub_type: 杂志文章
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journal_title:Journal of medical economics
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journal_title:Journal of medical economics
pub_type: 杂志文章
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journal_title:Journal of medical economics
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pub_type: 杂志文章,多中心研究
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journal_title:Journal of medical economics
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journal_title:Journal of medical economics
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更新日期:2015-06-01 00:00:00
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journal_title:Journal of medical economics
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journal_title:Journal of medical economics
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journal_title:Journal of medical economics
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journal_title:Journal of medical economics
pub_type: 杂志文章
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journal_title:Journal of medical economics
pub_type: 杂志文章
doi:10.3111/13696998.2012.675890
更新日期:2012-01-01 00:00:00