The role of discoidin domain receptor 2 in the renal dysfunction of alport syndrome mouse model.

abstract：:Between January and December 1996, we observed 64 children (mean age 8.3 years range 4.2 to 11.2 years) who required dialysis for severe acute renal failure secondary to Falciparum Malaria. All received anti malarial therapy and other supportive therapy as well as peritoneal dialysis. Out of these 28 died (43.8%). The...

journal_title：Renal failure

authors： Sheiban AK

更新日期：1999-01-01 00:00:00

abstract：:One of the most important characteristics of chronic renal failure (CRF) is its progression to end stage renal disease. CRF progression depends of many factors indicated in numerous experimental and clinical studies. The present study was undertaken with the aim to examine the role of sex, etiology of CRF, renal funct...

journal_title：Renal failure

authors： Jovanovic DB,Djukanovic L

更新日期：1999-03-01 00:00:00

abstract：:We explored urinary biomarkers as an alternative for measuring the effect of an experimental COX-2 inhibitor on renal function in volunteers. Thirty male volunteers between the ages of 20-40 were enrolled and a COX-2 NSAID was given in a blinded design. The acute administration of an oral COX-2 NSAID resulted in a con...

journal_title：Renal failure

authors： Porter GA,Norton TL,Legg V

更新日期：1999-05-01 00:00:00

abstract：:The results of many of human studies indicate that the genetics of the more common forms of renal disease are quite complex. There are indications that human renal disease may be both polygenic and heterogenic. There are several approaches. Some researchers studying small populations are collecting larger numbers of f...

journal_title：Renal failure

authors： Mueller PW

更新日期：1999-05-01 00:00:00

abstract：:We report on a patient with an eight-year history on maintenance hemodialysis treatment without residual renal function in whom pregnancy was successfully managed through to the 29th week. During this time, under carefully modified dialysis treatment, the nephrologic course, as well as materno-fetal flow relationships...

journal_title：Renal failure

authors： Reister F,Reister B,Heyl W,Riehl J,Schröder W,Mann H,Rath W

更新日期：1999-09-01 00:00:00

abstract：:The development of diabetic nephropathy shows remarkable variation among individuals. Therefore, not only hyperglycemia but also genetic factors may contribute to the development of diabetic nephropathy Heparan sulfate proteoglycan (HSPG) is thought to play an important role as a component of the charge selectivity ba...

journal_title：Renal failure

authors： Fujita H,Narita T,Meguro H,Ishii T,Hanyu O,Suzuki K,Ito S

更新日期：1999-11-01 00:00:00

abstract：:Previous studies showed that acute chloroquine administration increases plasma arginine vasopressin (AVP) concentration in the rat without influencing urine flow rate. The present study was designed to investigate whether chloroquine inhibits the AVP-induced cAMP production that mediates the antidiuretic effects of va...

journal_title：Renal failure

authors： Musabayane CT,Wargent ET,Balment RJ

更新日期：2000-01-01 00:00:00

abstract：:Ginsenoside-Rd has been proved to decrease the severity of renal injury induced by cisplatin, in which proximal urinaferous tubules represent the main site of injury. When ginsenoside-Rd was given orally at a dose of 1 or 5 mg/kg body weight/day for 30 consecutive days prior to cisplatin injection, the activities of t...

journal_title：Renal failure

authors： Yokozawa T,Liu ZW

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Prediction of which intensive care unit (ICU) patients are likely to develop acute renal failure (ARF) would be useful. However, scoring systems such as APACHE have been disappointing in this regard. We previously developed a bedside formula to predict ARF using only 3 parameters: serum albumin, urine osmola...

journal_title：Renal failure

authors： Coritsidis GN,Guru K,Ward L,Bashir R,Feinfeld DA,Carvounis CP

更新日期：2000-03-01 00:00:00

abstract：:Conditions associated with intravascular hemolysis are often complicated by acute renal failure which is characterized by renal vasoconstriction and tubular injury. However, the effects of human red blood cell (RBC) hemolysate on renal tubular epithelial cell function have not been well characterized. We therefore mea...

journal_title：Renal failure

authors： Anderson RJ,Ray CJ,Burke TJ

更新日期：2000-05-01 00:00:00

abstract：:The obese ZDFxSHHF-fa/fa(cp) model was developed by crossing lean female Zucker Diabetic Fatty (ZDF +/fa) and lean male Spontaneously Hypertensive Heart Failure (SHHF/Mcc-fa(cp), +/fa) rats. The purpose of the present study was to determine renal function and morphology, hemodynamics, and metabolic status in ZDFxSHHF ...

journal_title：Renal failure

authors： Tofovic SP,Kusaka H,Kost CK Jr,Bastacky S

更新日期：2000-01-01 00:00:00

abstract：:We encountered a 53-year-old man associated with acute renal failure caused by Waldenström's macroglobulinemia and type I cryoglobulinemia. Treatment with prednisolone and cyclophosphamide induced a rapid recovery from acute renal failure. Renal histology revealed endocapillary proliferation and lobular formation with...

journal_title：Renal failure

authors： Yonemura K,Suzuki T,Sano K,Fujigaki Y,Ikegaya N,Hishida A

更新日期：2000-01-01 00:00:00

abstract：:In neonatal myocytes grown in culture, reductions in extracellular potassium concentration produced a hypertrophic response as assessed by induction of early response genes, atrial natriuretic peptide and skeletal actin, and repression of the alpha3 isoform of the sodium pump in a dose dependent manner. The degree of ...

journal_title：Renal failure

authors： Xie Z,Liu J,Malhotra D,Sheridan T,Periyasamy SM,Shapiro JI

更新日期：2000-01-01 00:00:00

abstract：:Nephrotic patients with primary focal segmental glomerulosclerosis (FSGS) have a poor prognosis with 50% progressing to end stage renal disease (ESRD) over 3 to 8 years. The achievement of a remission in proteinuria has been associated with a significantly improved renal survival as compared to those patients not atta...

journal_title：Renal failure

authors： Korbet SM

更新日期：2000-11-01 00:00:00

abstract：:During advanced renal failure, and particularly in patients with end-stage renal disease, proteins are carbamylated as a result of a reaction with cyanate. If the carbamylation of proteins adversely alters their biologic activities and structures, then urea must be viewed as an uremic toxin, rather than a surrogate. T...

journal_title：Renal failure

authors： Mun KC,Kim HC,Kwak CS

更新日期：2000-11-01 00:00:00

abstract：INTRODUCTION:To study the functional and histological alterations in dog kidneys submitted to total ischemia for thirty minutes and the possible metoprolol protective action. MATERIAL AND METHODS:Sixteen dogs anesthetized with sodium pentobarbital (SP) were studied and divided into two groups: G1-8 dogs submitted to l...

journal_title：Renal failure

authors： Módolo NS,Castiglia YM,Ganem EM,Braz JR,Vianna PT,Vane LA

更新日期：2001-01-01 00:00:00

abstract：:The effect of Cyclosporin A on nitric oxide production was studied in cultured LLC- PK1 cells. For this purpose the cells were incubated with vehicle (olive oil, 10 microg/ml in DMSO), Cyclosporin A (CsA, 10 microg/ml), tumor necrosis factor (TNF-alpha, 150 U/ml) + interferon (IFN-gamma, 500 U/ml) to upregulate NOS sy...

journal_title：Renal failure

authors： Lima R,Serone AP,Schor N,Higa EM

更新日期：2001-01-01 00:00:00

abstract：:In Western society, the triad of hypertension, metabolic syndrome and obesity (which caries a high risk for renal disease) is increasing, as is the intake of caffeine. However, no information is available regarding the metabolic or renal consequences of caffeine consumption in this complex disease entity. The purpose ...

journal_title：Renal failure

authors： Tofovic SP,Kusaka H,Jackson EK,Bastacky SI

更新日期：2001-03-01 00:00:00

abstract：:Cyclooxygenase-2 (COX-2) is constitutively expressed in the macula densa of several laboratory animal species where it is considered to play a physiologic role in the regulation of basal renal function. Pertubations to normal homeostasis is shown to be associated with the upregulation of COX-2 in the macula densa of r...

journal_title：Renal failure

authors： Khan KN,Stanfield KM,Harris RK,Baron DA

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Cystatin C (MW 13kDa) serum concentration reflects glomerular filtration rate better than creatinine. Like other low-molecular weight proteins it is not eliminated by dialysis. Still, cystatin C serum concentrations do not rise progressively in end-stage renal failure and rarely exceed 10 mg/L (i.e. 8 times ...

journal_title：Renal failure

authors： Bökenkamp A,Ciarimboli G,Dieterich C

更新日期：2001-05-01 00:00:00

abstract：:Myofibroblasts play an important role in many tissue injuries, and particularly in renal disease. The myofibroblast differentiation is an early event in the development of fibrosis. Myofibroblast-like cells express smooth muscle (SM) cytoskeletal markers (alpha-SM actin in particular) and participate actively in the p...

journal_title：Renal failure

authors： Badid C,Vincent M,Fouque D,Laville M,Desmoulière A

更新日期：2001-05-01 00:00:00

abstract：:Hyperlipidemia is a common occurance in patients with chronic renal failure (CRF) and has been the subject of many clinical and experimental studies. Despite this, the role of lipogenesis in the development of hyperlipidemia is still obscure. The present study is based on a rat model of CRF involving a two-stage subto...

journal_title：Renal failure

authors： Szolkiewicz M,Kochan Z,Swierczynski J,Rutkowski B

更新日期：2001-09-01 00:00:00

abstract：:Autosomal dominant polycystic kidney disease is a disorder, which is inherited in 50% of offspring, irrelevant the sex and it has a variable clinical expressivity. Initially it was noticed that the clinical expression was interfamilial, but some studies found out that it was different. The aim of this study was to eva...

journal_title：Renal failure

authors： Sotirakopoulos N,Tsitsios T,Stambolidou M,Cristodoulidou C,Spaia S,Mavromatidis K

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:The serum aluminum (Al) measurement with desferrioxamine (DFO) mobilization is a screening test for uremic patients with an Al overload. In these patients, body iron status is one of the factors affecting the serum Al level. This study is designed to elucidate the effects of iron supplements on the serum Al ...

journal_title：Renal failure

authors： Huang JY,Wu MS,Wu CH

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Oxidative stress is known to be implicated in the pathogenesis of atherosclerotic cardiovascular disease. Many studies have demonstrated that hormone replacement therapy (HRT) has beneficial effects on oxidation injury in postmenopausal women with normal renal function. In this study, we examined the effects...

journal_title：Renal failure

authors： Chang SP,Yang WS,Lee SK,Min WK,Park JS,Kim SB

更新日期：2002-01-01 00:00:00

abstract：:We examined the effect of aqueous murine kidney extract (MKE) on the growth of mast cells prepared from the liquid culture of human umbilical cord blood CD34+ cells in the presence of a combination of recombinant human stem cell factor (SCF) and interleukin-6 (IL-6). Cultured cells were mature mast cells that expresse...

journal_title：Renal failure

authors： Murakami M,Kashiwakura I,Hayase Y,Takahashi TA,Takagi Y

更新日期：2002-03-01 00:00:00

abstract：:Atrial septal aneurysm (ASA) is a well known morphologic abnormality and has been largely investigated with both transthoracic (TTE) and/or transesophageal echocardiography (TEE). Its association with other congenital and acquired heart diseases and midsystolic clicks has been reported. ASA also may be associated with...

journal_title：Renal failure

authors： Acartürk E,Paydaş S,Akgül F

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:Treatment of anemia with recombinant human erythropoietin (rHuEpo) in hemodialysis patients has been associated with improvement of several abnormalities in hypothalamic-pituitary function. The aim of the present study is to investigate the effects of long term erythropoietin therapy on the hypothalamic-pitui...

journal_title：Renal failure

authors： Tokgöz B,Utaş C,Doğukan A,Oymak O,Keleştimur F

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:End-Stage renal disease is associated with accelerated atherosclerosis and a high incidence of cardiovascular disease. METHODS:The serum levels of lipids and apolipoproteins and Lp(a) were determined in 51 patients with chronic renal failure (CRF) with various advancement, without interference of factors wh...

journal_title：Renal failure

authors： Kimak E,Solski J

更新日期：2002-07-01 00:00:00

abstract：:Lipid abnormalities are important variables in the development of vascular atherosclerotic lesions in ESRD patients while Lp(a) represents an independent risk factor. In order to evaluate lipid changes in HD and CAPD patients, serum cholesterol (TC), HDLc, LDLc, TG, apolipoproteins (AI,AII,B,E), Lp(a), and albumin lev...

journal_title：Renal failure

authors： Fytili CI,Progia EG,Panagoutsos SA,Thodis ED,Passadakis PS,Sombolos KI,Vargemezis VA

更新日期：2002-09-01 00:00:00