The importance of pial blood supply to the development of peritumoral brain edema in meningiomas.

Abstract:

:In a retrospective analysis, the authors studied the pial and dural blood supplies in 74 intracranial meningiomas and quantified their associated peritumoral brain edema (PTBE). The extent and localization of pial blush in relation to the total tumor volume were determined angiographically. The amount of edema and tumor size were calculated using computerized tomography. The edema-tumor volume ratio was defined as Edema Index (EI). There were 49 meningiomas with PTBE; of those tumors, 46 were supplied by pial vessels, and three were supplied exclusively by dural vessels. Tumors without PTBE showed no pial blush. The mean EI in meningiomas with pial blush was significantly larger (EI = 3) than in meningiomas without pial supply (EI = 1.1; p < 0.0001). Meningiomas with a smaller pial supply than dural supply had a significantly smaller mean EI than tumors with a pial supply equal to or greater than the dural supply (EI = 2.9 vs. EI = 3.7; p < 0.015). In 69.9% of cases with pial blood supply, major portions of the edema were located adjacent to the tumor region supplied by pial vessels. Edema index differences among tumors of different subgroups, as defined by size or histology, were significantly related to the pial supply in each subset. Thus, pial blood supply may be associated with the development of PTBE in meningiomas.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Bitzer M,Wöckel L,Luft AR,Wakhloo AK,Petersen D,Opitz H,Sievert T,Ernemann U,Voigt K

doi

10.3171/jns.1997.87.3.0368

subject

Has Abstract

pub_date

1997-09-01 00:00:00

pages

368-73

issue

3

eissn

0022-3085

issn

1933-0693

journal_volume

87

pub_type

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