Recurrence of subsquamous dysplasia and carcinoma after successful endoscopic and radiofrequency ablation therapy for dysplastic Barrett's esophagus.

Abstract:

:Barrett's esophagus with dysplasia is commonly treated with radiofrequency ablation (RFA). Despite its effectiveness, a concern of any ablative technique is the development of subsquamous intestinal metaplasia, which could have potential for future neoplastic progression. To date, 34 cases of subsquamous neoplasia have been described in the literature after various ablation therapies. However, only three cases of subsquamous neoplasia have been reported after successful RFA treatment of dysplastic Barrett's esophagus. In this case series, we report on four additional cases of subsquamous neoplasia detected after successful endoscopic resection and RFA for neoplastic and dysplastic Barrett's esophagus. All four patients were treated successfully with endoscopic resection of their recurrent subsquamous neoplastic and dysplastic lesions. This case series highlights the need for continued surveillance following successful treatment of dysplastic Barrett's esophagus with RFA.

journal_name

Endoscopy

journal_title

Endoscopy

authors

Lee JK,Cameron RG,Binmoeller KF,Shah JN,Shergill A,Garcia-Kennedy R,Bhat YM

doi

10.1055/s-0032-1326419

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

571-4

issue

7

eissn

0013-726X

issn

1438-8812

journal_volume

45

pub_type

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