当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY期刊下所有文献 > Vasoconstrictive and analgesic efficacy of locally infiltrated levobupivacaine in tonsillectomy patients.

Vasoconstrictive and analgesic efficacy of locally infiltrated levobupivacaine in tonsillectomy patients.

Abstract：

OBJECTIVES:The use of preincisional plain levobupivacaine, lidocaine adrenaline and saline for perioperative blood loss and postoperative analgesia in pediatric tonsillectomy patients are compared. METHODS:Ninety patients were randomly assigned into one of the 3 groups to receive preincisional peritonsillar infiltration of levobupivacaine 0.25% (group LB), lidocaine-adrenaline 1% with 1:200,000 (group LA) and saline (group S) under general anesthesia. Intraoperative blood loss, pre- and postoperative hemoglobin (hb) and haematocrit (htc) values, hemostasis time, operation duration, number of cautery used (20 W, 1s) and heart rates were recorded. Pain scores in PACU, at 6th, 12th and 24th hours postoperatively and the number of the patients requiring analgesic treatment for first 24h was also recorded. RESULTS:There was a 30% reduction in perioperative blood loss in group LB and 63% reduction in group LA compared to group S (39 ± 6, 21 ± 4 and 55 ± 7 ml respectively) (p<0.001). Even though all three groups have significantly lower postoperative hb and htc values with respect to preoperative levels both local anesthetic groups had significantly higher postoperative hb and htc values than saline (p<0.001). Time required for hemostasis, the number of cautery used for haemostasis and operation duration were lower in groups LB and LA with respect to group S. Pain scores of the group LB revealed a significantly lower score throughout 24h. Only 14 patients in group LB demanded additional analgesic where as all patients in the other groups had. Adding adrenaline to the local anesthetic solution showed no side effects. Also we did not happened to see any complications related to local anesthetic injections. There was no postoperative major bleeding in groups. CONCLUSION:Levobupivacaine has a vasoconstrictive effect in 0.25% concentrations that may be beneficial in tonsillectomy patients and has a consistent analgesic effect.

journal_name

Int J Pediatr Otorhinolaryngol

journal_title

International journal of pediatric otorhinolaryngology

authors

Ergil J,Akkaya T,Gozaydin O,Gunsoy B,Alicura S,Aladag E,Gumus H,Akin I

doi

10.1016/j.ijporl.2012.06.016

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

1429-33

issue

eissn

0165-5876

issn

1872-8464

pii

S0165-5876(12)00371-0

journal_volume

pub_type

杂志文章,随机对照试验

在线工具

Vasoconstrictive and analgesic efficacy of locally infiltrated levobupivacaine in tonsillectomy patients.