The polymorphonuclear leukocyte: has it a role in fracture healing?

Abstract:

:The aim of the present study was to assess whether the presence of polymorphonuclear leukocytes in the first stage of fracture repair was of any importance. In anesthetized male Wistar rats, a transverse osteotomy was performed at midshaft in one femur and immediately stabilized by an intramedullary Kirschner nail. The animals were allowed unprotected weight bearing immediately. Nine animals were made neutropenic before operation by injection of a specific rat polymorphonuclear leukocyte antiserum (antineutrophil serum, ANS) raised in sheep. The number of circulating polymorphonuclear leukocytes were kept below 20% of their normal value for 72 h postoperatively by intraperitoneal injections of ANS every 12 h. Control animals were injected with the same amount of normal sheep serum (NSS). All animals received cefuroxime (100 mg/kg day) concomitantly with the ANS injections. Six weeks after operation the animals were killed, the amount of callus formation was measured, and the bones were radiologically examined. The nails were then removed and both the healing fractures and the nonoperated femurs mechanically tested for bending. There were no differences in the amount of callus measured or in radiological healing. However, there was a significantly higher bending moment in femurs from animals treated with ANS than in those given NSS (P less than 0.02). No differences were observed in rigidity or total energy absorption.

authors

Grøgaard B,Gerdin B,Reikerås O

doi

10.1007/BF00419942

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

268-71

issue

5

eissn

0936-8051

issn

1434-3916

journal_volume

109

pub_type

杂志文章
  • Autologous chondrocyte implantation versus ACI using 3D-bioresorbable graft for the treatment of large full-thickness cartilage lesions of the knee.

    abstract:BACKGROUND:In autologous chondrocyte implantation (ACI), the periosteum patch which is sutured over the cartilage defect has been identified as a major source of complications such as periosteal hypertrophy. In the present retrospective study, we compared midterm results of first-generation ACI with a periosteal patch ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-009-0957-y

    authors: Erggelet C,Kreuz PC,Mrosek EH,Schagemann JC,Lahm A,Ducommun PP,Ossendorf C

    更新日期:2010-08-01 00:00:00

  • Prophylaxis with oral cefadroxil versus intravenous cefuroxime in trochanteric fracture surgery. A clinical multicentre study.

    abstract::A prospective, randomized study was performed in 559 patients to compare two doses of oral cefadroxil with three doses of intravenous cefuorxime as antibiotic prophylaxis in intra- and subtrochanteric hip fracture surgery. Antibiotic concentrations in the wound fluid were determined at the start and at the end of the ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1007/BF00448952

    authors: Nungu KS,Olerud C,Rehnberg L,Larsson S,Nordell P,Allvin I,Bengtsson S,Wallinder L,Hedin G

    更新日期:1995-01-01 00:00:00

  • Cementation in the treatment of giant cell tumor of bone.

    abstract::This study was designed to review the clinical experience of cementation in the treatment of giant cell tumor of bone and to clarify its biologic basis. Eleven patients treated by this technique had results rated excellent. No recurrences of the tumor were found. Serious complications, including infection, late fractu...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/BF00420253

    authors: Komiya S,Inoue A

    更新日期:1993-01-01 00:00:00

  • No physiologic age-related increase of circulating somatomedin-C during early stage of Perthes' disease: a longitudinal study in 21 boys.

    abstract::Perthes' disease was originally viewed as a local ischaemic necrosis of the femoral head. Several authors, however, have presented data suggesting that children with this disease also suffer from a general disorder of skeletal maturation. Hormonal changes in the hypothalamus-pituitary-growth plate axis have been discu...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/BF00388093

    authors: Neidel J,Zander D,Hackenbroch MH

    更新日期:1992-01-01 00:00:00

  • Biomechanical comparison of screw-in suture anchor-suture combinations used for Bankart repair.

    abstract:INTRODUCTION:Bankart repair laxity may contribute to pathologic joint instability. This biomechanical study compared two screw-in suture anchor-suture combinations under tensile loads. METHODS:Twelve pairs of scapulae were implanted with either a 3 mm diameter, 14 mm long poly-L/D-lactide suture anchor with a suture e...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-009-0926-5

    authors: Sparks BS,Nyland J,Nawab A,Blackburn E,Krupp R,Caborn DN

    更新日期:2010-03-01 00:00:00

  • Minimally invasive internal fixator for unstable pelvic ring injuries with a pedicle screw-rod system: a retrospective study of 23 patients after 13.5 months.

    abstract:PURPOSE:Pelvic ring fractures are challenging injuries and require effective treatment due to the frequently compromised patient condition. The aim of this study was to evaluate the outcome of unstable pelvic ring injuries treated with a minimally invasive pedicle screw-rod system. METHODS:Retrospective analysis was p...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-018-3094-7

    authors: Hua X,Yan SG,Cui Y,Yin Z,Schreiner AJ,Schmidutz F

    更新日期:2019-04-01 00:00:00

  • No effects of piroxicam on osteopenia and recovery after Colles' fracture. A randomized, double-blind, placebo-controlled, prospective trial.

    abstract::In a randomized double-blind study involving 42 postmenopausal women with a displaced Colles' fracture, we investigated whether piroxicam, a nonsteroid anti-inflammatory drug, can reduce posttraumatic osteopenia and improve the rate of recovery. In an earlier study [3] we found a bone-sparing effect caused by piroxica...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF00449987

    authors: Adolphson P,Abbaszadegan H,Jonsson U,Dalén N,Sjöberg HE,Kalén S

    更新日期:1993-01-01 00:00:00

  • Conservative treatment after failure of internal fixation for periprosthetic femoral fractures: a report of two cases.

    abstract::Osteosynthesis using compression or locking plate following indirect fracture reduction and using a minimally invasive technique has been recommended for the surgical treatment of Vancouver B1 and C periprosthetic femoral fractures. Recent advancements in fracture healing emphasize the significance of the type of mech...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-015-2210-1

    authors: Choo SK,Kim Y,Shin MJ,Oh HK

    更新日期:2015-06-01 00:00:00

  • Case report. An unusual cause of a patient presenting with an acutely locked knee: multiple benign fat pad cysts.

    abstract::Benign ganglion (synovial) cysts within the knee are uncommon and especially so when located in the infrapatellar fad pad. They cause many non-specific symptoms but usually present as a swelling. We report the case of a young gentleman with multiple benign synovial cysts within the fat pad causing a locked knee, which...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-009-0838-4

    authors: Trompeter A,Servant C

    更新日期:2009-08-01 00:00:00

  • Two cases of closed dislocation of the interphalangeal joint of the thumb.

    abstract::Dorsal dislocation of the interphalangeal (IP) joint of the thumb is a rare injury, and closed dislocation without fracture is especially unusual. We present here two cases of closed dislocation of the thumb which were reduced by manipulation. ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/BF00434563

    authors: Nakae H,Endo S,Hoshi S

    更新日期:1996-01-01 00:00:00

  • Clinical and radiological outcomes after reverse shoulder arthroplasty with less medialized endoprosthesis after mean follow-up time of 45 months.

    abstract:INTRODUCTION:The purpose of this study was to evaluate outcomes after reverse shoulder arthroplasty for the treatment of complex three- and four-fragment proximal humeral fractures after mean follow-up time of 45 months and to compare our results with the results published by other authors. MATERIALS AND METHODS:Retro...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-017-2751-6

    authors: Jonušas J,Banytė R,Ryliškis S

    更新日期:2017-09-01 00:00:00

  • Low inter- and intraobserver variability allows for reliable tunnel measurement in ACL reconstruction using the quadrant method.

    abstract:INTRODUCTION:Correct anatomic tunnel positions are essential in anterior cruciate ligament (ACL) reconstruction. To establish recommendations for tunnel positioning based on anatomical findings and to compare tunnel positions with clinical results, different radiological measurement methods as the quadrant method exist...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-014-1931-x

    authors: Shafizadeh S,Balke M,Kelz S,Hoeher J,Banerjee M

    更新日期:2014-04-01 00:00:00

  • Stable clinical long term results after AMIC in the aligned knee.

    abstract:INTRODUCTION:The aim of this study was to report a long-term follow-up of patients treated with autologous matrix-induced chondrogenesis (AMIC) for full-thickness chondral and osteochondral defects of the femoral condyle or patella combined with the correction of lower limb malalignment or patellar tracking if indicate...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-020-03564-7

    authors: Kaiser N,Jakob RP,Pagenstert G,Tannast M,Petek D

    更新日期:2020-08-13 00:00:00

  • Laser engravings as reason for mechanical failure of titanium-alloyed total hip stems.

    abstract:INTRODUCTION:Two revisions of broken β-titanium total hip stems had to be performed in our hospital after 2 and 4 years in situ. Since both fractures were located at the level of a laser engraving, a failure analysis was conducted. MATERIALS AND METHODS:Both retrieved hip stems were disinfected and collected in our re...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-015-2225-7

    authors: Kluess D,Steinhauser E,Joseph M,Koch U,Ellenrieder M,Mittelmeier W,Bader R

    更新日期:2015-07-01 00:00:00

  • Septic arthritis of the hip in patients with femoral head osteonecrosis.

    abstract::Septic hip is rare in patients with femoral head osteonecrosis (FHON) and has been known to occur in those who are immune compromised. Thus, surgeons do not concern about the superimposed septic hip in immunocompetent patients. We report five patients who had FHON and concomitant septic arthritis of the hip. No patien...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-011-1334-1

    authors: Lee YK,Lee YJ,Ha YC,Kim KC,Koo KH

    更新日期:2011-11-01 00:00:00

  • The epidemic of ankle fractures in the elderly--is surgical treatment warranted?

    abstract::Ankle fractures in the elderly are extremely common (up to 184 fractures per 100,000 persons per year, and of these approximately 20%-30% occur in the elderly). The medical literature contains no research that has investigated ankle fractures in the elderly. A prospective, randomised study was conducted of 84 patients...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s004020000172

    authors: Salai M,Dudkiewicz I,Novikov I,Amit Y,Chechick A

    更新日期:2000-01-01 00:00:00

  • UKA after spontaneous osteonecrosis of the knee: a retrospective analysis.

    abstract:PURPOSE:Safety and efficacy of unicompartmental knee arthroplasty (UKA) in unicompartmental osteoarthritis (OA) has been shown in large patient series. It has been matter of discussion whether or not spontaneous osteonecrosis of the knee (SONK) can successfully be treated with UKA. PATIENTS AND METHODS:A retrospective...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-010-1177-1

    authors: Heyse TJ,Khefacha A,Fuchs-Winkelmann S,Cartier P

    更新日期:2011-05-01 00:00:00

  • Bipolar hip arthroplasty in ankylosing spondylitis.

    abstract::Nineteen severely affected hips in 12 young patients with ankylosing spondylitis were treated with bipolar hip arthroplasty followed by a comprehensive postoperative rehabilitation programme. Additional operative procedures of adductor tenotomy, knee flexion release, supracondylar femoral osteotomy for genu valgum and...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/BF00573449

    authors: Bhan S,Malhotra R

    更新日期:1996-01-01 00:00:00

  • Cement-in-cement revision hip arthroplasty: an analysis of clinical and biomechanical literature.

    abstract:INTRODUCTION:The number of revision hip arthroplasties is increasing but several aspects of this procedure could be improved. One method of reducing intra-operative complications is the cement-in-cement technique. This procedure entails cementing a smaller femoral prosthesis into the existing stable cement mantle. The ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章,评审

    doi:10.1007/s00402-007-0470-0

    authors: Keeling P,Prendergast PJ,Lennon AB,Kenny PJ

    更新日期:2008-10-01 00:00:00

  • Fractures of posterior wall of acetabulum.

    abstract::Fractures of the posterior wall of the acetabulum form a special group in acetabular fractures. This study aims to evaluate the results in the management of such fractures. Thirty-two patients with fractures of posterior wall of acetabulum were reviewed retrospectively. The follow-up period was 7 (range 3-10) years. T...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/BF00439052

    authors: Chiu FY,Lo WH,Chen TH,Chen CM,Huang CK,Ma HL

    更新日期:1996-01-01 00:00:00

  • Treatment of missed posterior dislocation of the shoulder by delayed open reduction and glenoid reconstruction with corticocancellous iliac bone autograft.

    abstract::This is a report of a 2-year follow-up of a missed posterior shoulder dislocation treated with open reduction and glenoid reconstruction with corticocancellous iliac bone autograft. In such cases, this treatment option may be an alternative to hemiarthroplasty of the shoulder. ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-004-0693-2

    authors: Bozkurt M,Can F,Dogan M,Solak S,Basbozkurt M

    更新日期:2004-07-01 00:00:00

  • Neglected rupture of the patellar tendon.

    abstract::Neglected rupture of the patellar tendon is a rare but well recognised complication of knee trauma. We present the case of a 43-year-old man who sustained a complete rupture of the patellar tendon of his left knee following a fall. Clinical diagnosis was delayed by 2 months and was confirmed by magnetic resonance imag...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s004020050401

    authors: Shepard GJ,Christodoulou L,Hegab AI

    更新日期:1999-01-01 00:00:00

  • The distal tibiofibular syndesmosis during passive foot flexion. RSA-based study on intact, ligament injured and screw fixed cadaver specimens.

    abstract:INTRODUCTION:The aim of the study was to investigate the kinematics of the distal tibiofibular syndesmosis in intact and ligament injured ankles and to assess how effective is the syndesmotic screw in restraining mortise width variations during passive foot flexion. MATERIALS AND METHODS:The trials were carried out on...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-006-0131-8

    authors: Bragonzoni L,Russo A,Girolami M,Albisinni U,Visani A,Mazzotti N,Marcacci M

    更新日期:2006-07-01 00:00:00

  • Three-to 7-year results with the uncemented SL femoral revision prosthesis.

    abstract::Between 1988 and 1991, 40 Wagner SL femoral revision stems were implanted at the Orthopaedic Departments of the University of Basel and of the Kantonsspital Liestal, Switzerland. The indications were: 27 cases of extensive bone resorption and destruction of the proximal prosthetic bed, seven periprosthetic fractures, ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/BF00393708

    authors: Grünig R,Morscher E,Ochsner PE

    更新日期:1997-01-01 00:00:00

  • Laminoplasty versus skip laminectomy for the treatment of multilevel cervical spondylotic myelopathy: a systematic review.

    abstract:INTRODUCTION:Laminoplasty and skip laminectomy are two specific posterior surgical approaches for multilevel cervical spondylotic myelopathy. The objective of this study was to perform a systematic review comparing the clinical results and complications of laminoplasty and skip laminectomy in the treatment of multileve...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章,评审

    doi:10.1007/s00402-013-1881-8

    authors: Yuan W,Zhu Y,Liu X,Zhou X,Cui C

    更新日期:2014-01-01 00:00:00

  • Arthroscopic bare spot method underestimates true bone defect in bony Bankart lesion.

    abstract:INTRODUCTION:The need for precise quantification of the glenoid defect should be emphasized in the choice of surgery for bony Bankart lesion especially in its critical values of 16% to 25. The study aims to verify the validity of bare spot method for arthroscopic quantification of glenoid bone defect using several vari...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-019-03195-7

    authors: Kho J,Kholinne E,Lim S,Hong H,Kwak JM,Sun Y,Koh KH,Jeon IH

    更新日期:2019-09-01 00:00:00

  • The longer pull-out suture as a transmission suture for early active motion of repaired flexor tendon at the proximal zone-2.

    abstract:OBJECTIVES:The purpose of the current study was to clinically evaluate the technique of longer pull-out suture as a transmission suture for early active motion after flexor tendon repair in the proximal zone-2. METHOD:Eleven patients (eight adult male, two adult female and one child) with 19 proximal zone II flexor te...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-010-1238-5

    authors: Okçesiz IE,Ege A,Turhan E,Songür M,Bayar A,Keser S

    更新日期:2011-04-01 00:00:00

  • Cervical myelo-radiculopathy in athetoid cerebral palsy.

    abstract::Cervical myelopathy complicating athetoid cerebral palsy has not been adequately highlighted in the literature. We report two cases of patients with athetoid cerebral palsy and long histories of involuntary movements who developed cervical myelo-radiculopathy. Dystonic athetoid neck movements may cause excessive axial...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/BF00434115

    authors: Mikawa Y,Watanabe R,Shikata J

    更新日期:1997-01-01 00:00:00

  • Clinical features and surgical outcomes of lumbar spinal stenosis in patients aged 80 years or older: a multi-center retrospective study.

    abstract:INTRODUCTION:With increased aging of the population, spine surgeons have more opportunity to treat elderly patients for lumbar spinal stenosis (LSS). The purpose of this study was to clarify the clinical features and surgical outcomes for LSS in the elderly aged 80 years or older. MATERIALS AND METHODS:We retrospectiv...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00402-013-1808-4

    authors: Nanjo Y,Nagashima H,Dokai T,Hamamoto Y,Hashiguchi H,Ishii H,Kameyama Y,Morio Y,Murata M,Tanida A,Tanishima S,Teshima R

    更新日期:2013-09-01 00:00:00

  • A concept for comprehensively measuring health, function and quality of life following orthopaedic interventions of the upper extremity.

    abstract::The view that subjective complaints rather than "objective" measurements decide on whether to consult the doctor or allow for an intervention to be carried out, should contribute to the decision-making process. This is especially true in diseases with multiple joint impairments. Although a variety of patient self-asse...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-008-0718-3

    authors: Simmen BR,Angst F,Schwyzer HK,Herren DB,Pap G,Aeschlimann A,Goldhahn J

    更新日期:2009-01-01 00:00:00