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Outcomes of laparoscopic colon cancer surgery in a population-based cohort in British Columbia: are they as good as the clinical trials?

Abstract：

BACKGROUND:Randomized controlled trials have shown equivalent outcomes for laparoscopic-assisted colectomy (LAC) and open colectomy (OC) when performed by well-trained surgeons experienced in both techniques. Our goal was to evaluate the outcomes of LAC at a population level. METHODS:Using the prospectively collected Gastrointestinal Cancer Outcomes Unit database from the British Columbia Cancer Agency, short- and long-term outcomes in patients with colon cancer treated with LAC and OC were compared from 2003 to 2008 inclusive. RESULTS:There was a statistically significant increase in the proportion of LAC from 2003 to 2008 (P < .001). LAC was more likely to be performed in the elective setting (P < .001) and for smaller tumors (P < .001). A similar proportion of patients had a minimum of 12 lymph nodes identified by pathology (58% vs 60%, P = not significant). Disease-free survival was similar for the 2 groups after adjusting for stage, emergency presentation, and adjuvant chemotherapy. There was no difference in overall survival. CONCLUSIONS:The introduction of LAC for colon cancer in British Columbia outside of optimized clinical trial conditions appears to be effective and safe.

journal_name

Am J Surg

journal_title

American journal of surgery

authors

Aslani N,Lobo-Prabhu K,Heidary B,Phang T,Raval MJ,Brown CJ

doi

10.1016/j.amjsurg.2011.11.015

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

411-5

issue

4

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(12)00207-3

journal_volume

204

pub_type

杂志文章

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