Site and size of bleeding peptic ulcer. Is there any relation to the efficacy of hemostatic sclerotherapy?

Abstract:

:In 78 patients with high-risk bleeding peptic ulcers (either with active bleeding or non-bleeding visible vessel) endoscopic hemostasis by injection of adrenaline and polidocanol was attempted. Sclerotherapy was performed in 70 (90%) patients. Initial hemostasis was achieved in 35 (94.5%) patients with active bleeding, and permanent hemostasis in 61 (87%). Efficacy of injection therapy was significantly lower in ulcers larger than 2 cm (p = 0.001), and in those located on the posteroinferior duodenal wall (p = 0.03). It was not possible to perform endoscopic injection in 8 (10%) patients due to difficulty of access, lesions located mainly high on the lesser gastric curvature and on the posteroinferior duodenal wall. From these results we conclude that endoscopic injection is a very useful technique for the initial treatment of high-risk bleeding peptic ulcer, although the size and anatomical location of the lesions may be a limitation of its use.

journal_name

Endoscopy

journal_title

Endoscopy

authors

Brullet E,Campo R,Bedos G,Barcons S,Gubern JM,Bordas JM

doi

10.1055/s-2007-1010616

subject

Has Abstract

pub_date

1991-03-01 00:00:00

pages

73-5

issue

2

eissn

0013-726X

issn

1438-8812

journal_volume

23

pub_type

杂志文章
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    doi:10.1055/s-2007-1018237

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  • A variant of an accessory common bile duct.

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    doi:10.1055/s-2007-1018585

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