Sclerotherapy of varicose veins in patients with documented thrombophilia: a prospective controlled randomized study of 105 cases.

Abstract:

OBJECTIVES:The aim of this study was to assess thrombotic complications following sclerotherapy in thrombophilic patients in combination with thromboprophylaxis, in two randomized arms using low molecular weight heparin (LMWH) or warfarin. Patients and methods This study received approval from the Ethics Committee. A total of 105 patients (81 females, 24 males) ranging in age from 20 to 82 years (mean 50) were selected: 75 with Factor V Leiden mutation, 18 with prothrombin 20210A mutation, 7 with high level of Factor VIII, 5 combinations of these. After randomization, 51 and 54 patients received warfarin and LMWH, respectively. A total of 199 sclerotherapy sessions were performed. Foam was used in 160 treatments. RESULTS:No episodes of symptomatic deep vein thrombosis (DVT) or pulmonary embolism (PE) occurred; no instances of DVT were revealed by ultrasound-monitoring. CONCLUSIONS:This study suggests that in the three most common forms of thrombophilia, sclerotherapy, in combination with thromboprophylaxis, can be performed safely. Prophylaxis with LMWH is easier to use than warfarin.

journal_name

Phlebology

journal_title

Phlebology

authors

Hamel-Desnos CM,Gillet JL,Desnos PR,Allaert FA

doi

10.1258/phleb.2009.008081

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

176-82

issue

4

eissn

0268-3555

issn

1758-1125

pii

24/4/176

journal_volume

24

pub_type

杂志文章,多中心研究,随机对照试验
  • Early re-presentations and the potential role of catheter-directed thrombolysis in patients diagnosed with a lower limb deep vein thrombosis: a single-centre experience.

    abstract:INTRODUCTION:Catheter-directed thrombolysis (CDT) for iliofemoral deep vein thrombosis (DVT) restores venous patency, reduces the risk of the post-thrombotic syndrome and may reduce longer term treatment costs. This study assessed the potential role of CDT in patients with DVT with regard to representation following th...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1258/phleb.2012.012078

    authors: Chandra E,Ahmadi M,Bailey MA,Griffin KJ,Berridge DC,Coughlin PA,Scott DJ

    更新日期:2013-12-01 00:00:00

  • Variations in ultrasound scanning protocols in the UK for suspected deep vein thrombosis in outpatients.

    abstract:AIMS:To assess current ultrasound scanning protocol in outpatients with suspected deep vein thrombosis (DVT), in particular whether practitioners routinely scanned calf veins. METHODS:A standard questionnaire was sent out via post to all radiology departments in the United Kingdom (UK) and via the British Medical Ultr...

    journal_title:Phlebology

    pub_type: 临床试验,杂志文章

    doi:10.1177/0268355513501608

    authors: Shahi F,Murali K

    更新日期:2013-12-01 00:00:00

  • Ultrastructure of internal jugular vein defective valves.

    abstract:OBJECTIVES:To study the ultrastructure of intraluminal defects found in the internal jugular vein by using a scanning electron microscopy. METHODS:Using a scanning electron microscopy, intraluminal septa and/or defective valves blocking the flow in the distal internal jugular vein of seven patients were studied togeth...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1177/0268355514541980

    authors: Zamboni P,Tisato V,Menegatti E,Mascoli F,Gianesini S,Salvi F,Secchiero P

    更新日期:2015-10-01 00:00:00

  • First Dutch guidelines on lipedema using the international classification of functioning, disability and health.

    abstract::Introduction Lipedema is a chronic, progressive condition that can result in considerable disability. In 2011, the Dutch Society of Dermatology and Venereology organized a task force to create guidelines on lipedema, using the International Classification of Functioning, Disability and Health of the World Health Organ...

    journal_title:Phlebology

    pub_type: 杂志文章,评审

    doi:10.1177/0268355516639421

    authors: Halk AB,Damstra RJ

    更新日期:2017-04-01 00:00:00

  • Clinical profile and management of external jugular vein aneurysms.

    abstract:OBJECTIVE:External jugular vein (EJV) aneurysm is an extremely uncommon clinical condition. We have studied the clinical profile and need for surgery in this present seven case series of primary external jugular vein aneurysms. METHOD:Over the past three years, we have diagnosed and managed aneurysms of external jugul...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1177/0268355520975583

    authors: Thakur UK,Savlania A,Naik AL,Singh C,Chatterjee D,Gorsi U

    更新日期:2020-11-28 00:00:00

  • Venous tonus enhancement after a short cycle of intermittent pneumatic compression.

    abstract:OBJECTIVES:To test if intermittent pneumatic compression (IPC) used with a short cycle could reproduce and confirm the 30 min vasoconstriction effect observed after a long cycle of pressure. METHODS:Eighteen subjects took part in the study, 12 with venous insufficiency (VI) and six without VI (NonVI). Duplex scanner w...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1258/phleb.2007.007021

    authors: Harfouche JN,Theys S,Hanson P,Schoevaerdts JC,Sturbois X

    更新日期:2008-01-01 00:00:00

  • Patterns in the management of superficial vein thrombosis.

    abstract::Objective To highlight current practice patterns in management of superficial vein thrombosis. Methods An electronic survey was conducted using the mailing lists of the Mediterranean League of Angiology and Vascular Surgery and European Venous Forum regarding superficial vein thrombosis diagnosis, investigation, and t...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1177/0268355516641003

    authors: Karathanos C,Spanos K,Lachanas V,Athanasoulas A,Giannoukas AD

    更新日期:2017-04-01 00:00:00

  • Treatment of severe chronic venous insufficiency with ultrasound-guided foam sclerotherapy: a two-year series in a single center in Brazil.

    abstract:OBJECTIVES:To portray the initial experience at a public health center of the Federal District of Brazil in the treatment of chronic venous insufficiency with ultrasound-guided foam sclerotherapy in patients in advanced stages of the disease. METHOD:Eighty-seven reports of patients in C5 and C6 stages, according to CE...

    journal_title:Phlebology

    pub_type: 临床试验,杂志文章

    doi:10.1177/0268355513517225

    authors: Neto FC,de Araújo GR,Kessler IM,de Amorim RF,Falcão DP

    更新日期:2015-03-01 00:00:00

  • From lymph to fat: complete reduction of lymphoedema.

    abstract::Liposuction for late-stage lymphoedema remains a controversial technique. While it is clear that conservative therapies such as combined decongestive therapy (CDT) and controlled compression therapy (CCT) should be tried in the first instance, options for the treatment of late-stage lymphoedema that is not responding ...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1258/phleb.2010.010s08

    authors: Brorson H

    更新日期:2010-10-01 00:00:00

  • Non-infected, non-haematic fluid collections after endovenous laser ablation of the saphenous veins: a noteworthy complication.

    abstract:OBJECTIVES:To describe an uncommon complication after endovenous laser ablation (EVLA) of the saphenous veins and its percutaneous management. METHODS:Symptomatic greater saphenous vein reflux was successfully treated by EVLA using standard technique. Local pain, redness and swelling around the prior percutaneous acce...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1258/phleb.2007.007041

    authors: Janne D'Othée B,Ghiorse D

    更新日期:2008-01-01 00:00:00

  • Catheter-directed foam sclerotherapy, an alternative to ultrasound-guided foam sclerotherapy for varicose vein treatment: A systematic review and meta-analysis.

    abstract:PURPOSE:Catheter-directed foam sclerotherapy is a new addition to the treatment modalities available for varicose veins. As a modification of ultrasound-guided foam sclerotherapy, catheter-directed foam sclerotherapy has been purported to offer higher complete ablation rates and an improved safety profile. The aim of t...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1177/0268355519898309

    authors: Lim SY,Tan JX,D'Cruz RT,Syn N,Chong TT,Tang TY

    更新日期:2020-07-01 00:00:00

  • Two-year follow-up of first human use of cyanoacrylate adhesive for treatment of saphenous vein incompetence.

    abstract:OBJECTIVES:To evaluate the safety and effectiveness of endovenous cyanoacrylate-based embolization of incompetent great saphenous veins. METHODS:Incompetent great saphenous veins in 38 patients were embolized by cyanoacrylate bolus injections under ultrasound guidance without the use of perivenous tumescent anesthesia...

    journal_title:Phlebology

    pub_type: 临床试验,杂志文章

    doi:10.1177/0268355514532455

    authors: Almeida JI,Javier JJ,Mackay EG,Bautista C,Cher DJ,Proebstle TM

    更新日期:2015-07-01 00:00:00

  • Wound care in venous ulcers.

    abstract::Wound dressings: ulcer dressings should create and maintain a moist environment on the ulcer surface. It has been shown that in an ulcer with a hard crust and desiccated bed, the healing process is significantly slowed and sometimes completely blocked so favouring infection, inflammation and pain. In contrast a moist ...

    journal_title:Phlebology

    pub_type: 杂志文章,评审

    doi:10.1177/0268355513477015

    authors: Mosti G

    更新日期:2013-03-01 00:00:00

  • The efficiency of O-(beta-hydroxyethyl)-rutosides in reducing the incidence of superficial venous insufficiency in patients with calf muscle pump dysfunction.

    abstract::Objective We aimed to evaluate the efficiency of O-(beta-Hydroxyethyl)-rutosides (Oxerutin) in reducing the incidence of venous system disease among patients with calf muscle pump dysfunction secondary to immobilization due to lower-limb fractures. Methods A total of 60 patients with lower-limb fractures and immobiliz...

    journal_title:Phlebology

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/0268355516635466

    authors: Yildiz CE,Conkbayir C,Huseynov E,Sayin OA,Tok O,Kaynak G,Cebi D,Ugurlucan M,Kantarci F,Inan M

    更新日期:2017-04-01 00:00:00

  • Competent and incompetent calf perforators in primary varicose veins: a resistant myth.

    abstract::The pathophysiology of calf perforators is presented. Bidirectional flow within calf perforators with a prevailing inward, into deep veins oriented component arises during calf pump activity in varicose vein patients, as evidenced by venous pressure measurements, plethysmographic findings, duplex ultrasonography, and ...

    journal_title:Phlebology

    pub_type: 杂志文章,评审

    doi:10.1177/0268355515610041

    authors: Recek C

    更新日期:2016-09-01 00:00:00

  • Popliteal venous aneurysm: a report on three cases presenting with chronic venous insufficiency without embolic events.

    abstract:OBJECTIVES:Popliteal venous aneurysms (PVA) are rare, but represent a significant potential source of thromboembolus. Most often the patients present with pulmonary embolism, which can also be detected in patients presenting with chronic venous insufficiency. METHODS:Three patients without any clinical evidence of pul...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1258/026835507780346204

    authors: Christenson JT

    更新日期:2007-01-01 00:00:00

  • Compression in mixed ulcers: venous side.

    abstract:INTRODUCTION:arterial involvement may coexist in about 15-30 of venous ulcers. In this case compression therapy maybe applied, only by expert caregivers, with a reduced pressure which must not overcome the arterial pressure at ankle and foot level. It remains to assess if such a reduced pressure may be effective also o...

    journal_title:Phlebology

    pub_type: 评审

    doi:10.1177/0268355514526676

    authors: Mosti G

    更新日期:2014-05-01 00:00:00

  • Clarivein mechanochemical ablation of the great and small saphenous vein: Early treatment outcomes of two hospitals.

    abstract:OBJECTIVES:Mechanochemical endovenous ablation is a novel technique for the treatment of great saphenous vein and small saphenous vein incompetence which combines mechanical injury of the endothelium with simultaneous infusion of liquid sclerosant. The main objective of this study was to evaluate early occlusion. METH...

    journal_title:Phlebology

    pub_type: 杂志文章,多中心研究

    doi:10.1177/0268355515600573

    authors: Deijen CL,Schreve MA,Bosma J,de Nie AJ,Leijdekkers VJ,van den Akker PJ,Vahl A

    更新日期:2016-04-01 00:00:00

  • Compression for the management of venous leg ulcers: which material do we have?

    abstract::Compression therapy is the most important basic treatment modality in venous leg ulcers. The review focusses on the materials which are used: 1. Compression bandages, 2. Compression stockings, 3. Self-adjustable Velcro-devices, 4. Compression pumps, 5. Hybrid devices. Compression bandages, usually applied by trained s...

    journal_title:Phlebology

    pub_type: 评审

    doi:10.1177/0268355514528129

    authors: Partsch H

    更新日期:2014-05-01 00:00:00

  • Inferior vena cava filters utilization in patients with venous thromboembolism: Analysis of a database of a tertiary hospital.

    abstract:PURPOSE:The aim of the study was to assess the inferior vena cava filter (IVCF) utilization in patients with venous thromboembolism (VTE) in tertiary care. METHODS:We performed a retrospective analysis of database of a tertiary hospital in 2016-2017. All the records of patients admitted for VTE or diagnosed with VTE b...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1177/0268355520975582

    authors: Arslanbekov MM,Efremova OI,Lebedev IS,Kirienko AI,Zolotukhin IA

    更新日期:2020-12-13 00:00:00

  • Prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: a blinded sonographic evaluation.

    abstract:OBJECTIVES:To verify the prevalence of chronic cerebrospinal venous insufficiency in patients affected by different clinical forms of multiple sclerosis and in healthy subjects using the Zamboni ultrasound protocol combined with M-mode ultrasound examination. MATERIALS AND METHODS:We enrolled 112 patients with multipl...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1177/0268355513512823

    authors: Tromba L,Blasi S,Vestri A,Kiltzanidi D,Tartaglia F,Redler A

    更新日期:2015-02-01 00:00:00

  • Does prescription of medical compression prevent development of post-thrombotic syndrome after proximal deep venous thrombosis?

    abstract:AIM:The aim of this review is to try to explain the controversy by critical analysis of previously published randomized controlled trials on the value of elastic compression stockings in the treatment of acute proximal deep vein thrombosis in prevention of post-thrombotic syndrome, which forms the scientific basis for ...

    journal_title:Phlebology

    pub_type: 杂志文章,评审

    doi:10.1177/0268355515585437

    authors: Perrin M,Eklöf B

    更新日期:2016-04-01 00:00:00

  • Valsalva maneuver in phlebologic practice.

    abstract::Forced expiration against an airway obstruction was originally described as a method for inflating the Eustachian tubes and is accredited to Antonio Maria Valsalva (1666-1723). The Valsalva maneuver is commonly applied for different diagnostic purposes. Its use for phlebologic diagnosis is the object this review. Veno...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1177/0268355516678513

    authors: Ricci S,Moro L,Minotti GC,Incalzi RA,De Maeseneer M

    更新日期:2018-03-01 00:00:00

  • Clarivein® mechano-chemical ablation an interim analysis of a randomized controlled trial dose-finding study.

    abstract:OBJECTIVES:The ClariVein® system is an endovenous technique that uses mechano-chemical ablation to treat incompetent truncal veins. This study was conducted to identify the ideal Polidocanol dosage and form for mechano-chemical ablation in order to occlude the great saphenous vein. When adhering to safe dosage levels, ...

    journal_title:Phlebology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1177/0268355515599692

    authors: Lam YL,Toonder IM,Wittens CH

    更新日期:2016-04-01 00:00:00

  • Retrospective cohort study for evaluating the INR monitoring patterns in patients with deep vein thrombosis in daily practice: Analysis of 2010-2013 database of a tertiary care center.

    abstract:OBJECTIVE:To evaluate the international normalized ratio (INR) monitoring patterns in patients with deep vein thrombosis. METHODS:Of 32,012 patients with ≥1 outpatient INR measurement and 42,582 patients with confirmed deep vein thrombosis diagnosis registered to our hospital between 1 January 2010 and 31 December 201...

    journal_title:Phlebology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1177/0268355518806117

    authors: Sargin M,Tasdemir MM,Kuplay H,Erdogan SB,Tandogar N,Akansel S,Kurc E,Orhan G,Aka SA

    更新日期:2019-06-01 00:00:00

  • Is there a continuing role for traditional surgery?

    abstract::Despite recent NICE guidance there remains a definite role for surgery in the management of varicose veins. A lot of the available evidence that has driven the transformation of care towards endovenous treatments is of good quality yet published by enthusiasts. No endovenous studies have reported long term results as ...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1177/0268355515589248

    authors: Coughlin PA,Berridge DC

    更新日期:2015-11-01 00:00:00

  • Our early experience with iliofemoral vein stenting in patients with post-thrombotic syndrome.

    abstract:INTRODUCTION:Venous balloon dilation and stent therapy have been proposed as effective treatments for chronic iliofemoral thrombosis. In this study, we report our experience and describe the one-year outcome and efficacy of balloon angioplasty and stenting for the treatment of post-thrombotic syndrome (PTS) in iliofemo...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1177/0268355513477641

    authors: Sarici IS,Yanar F,Agcaoglu O,Ucar A,Poyanli A,Cakir S,Aksoy SM,Kurtoglu M

    更新日期:2014-06-01 00:00:00

  • Use of the VENOVO™ and Sinus Obliquus™ venous stents in the treatment of non-thrombotic or post-thrombotic iliac vein lesions - Short-term results from a multi-centre Asian cohort.

    abstract:OBJECTIVES:Deep venous stenting with intravascular ultrasound (IVUS) guidance is gaining favour as the treatment modality of choice for symptomatic ilio-femoral venous occlusive disease. The aim was to determine the short-term patency and symptomatic relief gained using the Bard Venovo™ and Optimed Sinus Obliquus™ sten...

    journal_title:Phlebology

    pub_type: 杂志文章

    doi:10.1177/0268355520946219

    authors: Tang TY,Lim MH,Damodharan K,Yap CJ,Lee SQ,Yap HY,Chong TT,Tan JW

    更新日期:2021-02-01 00:00:00

  • The superficial venous system of the lower extremity: new nomenclature.

    abstract::The phlebology in the area of lower limbs is the only medical field in which the terminological needs of clinicians were met. Ten years ago, the latest revision of the Latin anatomical nomenclature, Terminologia Anatomica (TA), was issued. But almost none of the chapters reflected the clinicians' need to be a relevant...

    journal_title:Phlebology

    pub_type: 杂志文章,评审

    doi:10.1258/phleb.2009.009046

    authors: Kachlik D,Pechacek V,Baca V,Musil V

    更新日期:2010-06-01 00:00:00

  • Epidemiology, risk factors and sequelae of venous thromboembolism.

    abstract::The aim of this review was to discuss the epidemiology, risk factors and sequelae of venous thromboembolism (VTE). VTE has an incidence of 1-2 per 1000 people annually. The risk of VTE increases with age and is highest in Caucasians and African Americans. Combined oral contraceptives (COC), especially the third-genera...

    journal_title:Phlebology

    pub_type: 杂志文章,评审

    doi:10.1258/phleb.2012.012s31

    authors: Wong P,Baglin T

    更新日期:2012-01-01 00:00:00