Abstract：
INTRODUCTION:It has been shown that procalcitonin (PCT) is a good marker for sepsis as the more severe the infection the higher the plasma levels. The Mannheim peritonitis index (MPI) is very effective in assessing the prognosis of secondary peritonitis. The aim of this study is to find out whether there is any correlation between preoperative PCT levels and the postoperative MPI, as well as the prognostic value of preoperative PCT levels. PATIENTS AND METHOD:Prospective study of 57 patients operated on between December 2006-August 2008 for secondary peritonitis and classified into three groups (A: 23 patients, B: 24 patients and C: 10 patients) from lowest to highest severity of MPI. The preoperative values of procalcitonin were obtained with PCT-Q test (BRAHMS). RESULTS:PCT-Q was normal (<0.5ng/ml) in 19 patients in group A, in 2 patients in group B and none in group C (p<0.001). PCT-Q between 2-10ng/ml were found in one patient in group A, 13 in group B and none in group C (p<0.001). PCT-Q >10ng/ml were found in 10 cases in group C, 6 in group B and none in group A (p<0.001). Of the 19 patients admitted to the intensive care unit, the PCT-Q was >10ng/ml in 15 cases vs a PCT-Q<10mg/ml (p<0.001) in 4 cases. Seven patients died, all of them with a PCT-Q >10mg/ml (p<0.001). CONCLUSIONS:The correlation between preoperative PCT-Q and postoperative MPI is positive and significant. The values of PCT-Q are higher as the MPI severity increases. Values >10ng/ml are significant for admission to the ICU and a poor clinical prognosis.
journal_name
Cir Espjournal_title
Cirugia espanolaauthors
Viñas Trullen X,Rodríguez López R,Porta Pi S,Salazar Terceros D,Macarulla Sanz E,Besora Canal P,Alvarez Tellez F,Iglesias Castro C,Feliu Palá Xdoi
10.1016/j.ciresp.2009.02.007subject
Has Abstractpub_date
2009-07-01 00:00:00pages
24-8issue
1eissn
0009-739Xissn
1578-147Xpii
S0009-739X(09)00209-7journal_volume
86pub_type
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