Abstract:
:Leydig cell morphological changes were evaluated using morphometric and stereological methods in male mice exposed to low doses of cadmium. A possible reversibility of the changes after cadmium withdrawal was also considered. Nuclear morphological parameters and stereological densities of the Leydig cell population were lower in the cadmium-exposed groups than in the control. The withdrawal of cadmium did not lead to any significant recovery of the morphological parameters. Nevertheless, numerical density increased significantly in the withdrawn groups, suggesting that the hyperplasia of interstitial cells could try to relieve morphological damage after cadmium withdrawal.
journal_name
Bull Environ Contam Toxicoljournal_title
Bulletin of environmental contamination and toxicologyauthors
Blanco A,Moyano MR,Molina AM,Blanco C,Flores-Acuña R,García-Flores JR,Espada M,Monterde JGdoi
10.1007/s00128-009-9700-1subject
Has Abstractpub_date
2009-06-01 00:00:00pages
756-60issue
6eissn
0007-4861issn
1432-0800journal_volume
82pub_type
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journal_title:Bulletin of environmental contamination and toxicology
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