Abstract:
BACKGROUND:Functional Magnetic Resonance Imaging (fMRI) has been proven to be useful for studying brain functions. However, due to the existence of noise and distortion, mapping between the fMRI signal and the actual neural activity is difficult. Because of the difficulty, differential pattern analysis of fMRI brain images for healthy and diseased cases is regarded as an important research topic. From fMRI scans, increased blood ows can be identified as activated brain regions. Also, based on the multi-sliced images of the volume data, fMRI provides the functional information for detecting and analyzing different parts of the brain. METHODS:In this paper, the capability of a hierarchical method that performed an optimization algorithm based on modified maximum model (MCM) in our previous study is evaluated. The optimization algorithm is designed by adopting modified maximum correlation model (MCM) to detect active regions that contain significant responses. Specifically, in the study, the optimization algorithm is examined based on two groups of datasets, dyslexia and healthy subjects to verify the ability of the algorithm that enhances the quality of signal activities in the interested regions of the brain. After verifying the algorithm, discrete wavelet transform (DWT) is applied to identify the difference between healthy and dyslexia subjects. RESULTS:We successfully showed that our optimization algorithm improves the fMRI signal activity for both healthy and dyslexia subjects. In addition, we found that DWT based features can identify the difference between healthy and dyslexia subjects. CONCLUSION:The results of this study provide insights of associations of functional abnormalities in dyslexic subjects that may be helpful for neurobiological identification from healthy subject.
journal_name
BMC Med Inform Decis Makjournal_title
BMC medical informatics and decision makingauthors
Ji SY,Ward K,Najarian Kdoi
10.1186/1472-6947-9-S1-S6subject
Has Abstractpub_date
2009-11-03 00:00:00pages
S6issn
1472-6947pii
1472-6947-9-S1-S6journal_volume
9 Suppl 1pub_type
杂志文章abstract:BACKGROUND:Transient ischemic attack (TIA) is a brief episode of neurological dysfunction resulting from cerebral ischemia not associated with permanent cerebral infarction. TIA is associated with high diagnostic errors because of the subjective nature of findings and the lack of clinical and imaging biomarkers. The go...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-020-01154-6
更新日期:2020-06-18 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-019-0812-1
更新日期:2019-05-02 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-016-0295-2
更新日期:2016-07-18 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-3-4
更新日期:2003-05-07 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-015-0132-z
更新日期:2015-02-07 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-11-13
更新日期:2011-02-17 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-5-1
更新日期:2005-01-07 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-014-0099-1
更新日期:2014-11-25 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-017-0566-6
更新日期:2017-12-19 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-020-01258-z
更新日期:2020-09-29 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-12-S1-S5
更新日期:2012-04-30 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-016-0246-y
更新日期:2016-01-26 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-018-0697-4
更新日期:2018-11-20 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-13-134
更新日期:2013-12-09 00:00:00
abstract::After publication of this supplement article [1], it is requested the grant ID in the Funding section should be corrected from NSF grant IIS-7811367 to NSF grant IIS-1902617. ...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章,已发布勘误
doi:10.1186/s12911-020-1096-1
更新日期:2020-04-28 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-6-13
更新日期:2006-03-07 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-019-0781-4
更新日期:2019-04-04 00:00:00
abstract:BACKGROUND:A variety of multimodal treatment options are available for colorectal cancer and many patients want to be involved in decisions about their therapies. However, their desire for autonomy is limited by lack of disease-specific knowledge. Visual aids may be helpful tools to present complex data in an easy-to-u...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章,随机对照试验
doi:10.1186/1472-6947-12-118
更新日期:2012-10-23 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-017-0433-5
更新日期:2017-04-26 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-021-01392-2
更新日期:2021-01-28 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-12-32
更新日期:2012-04-13 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-13-S1-S1
更新日期:2013-01-01 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-8-28
更新日期:2008-06-25 00:00:00
abstract:BACKGROUND:We developed Supportive care Prioritization, Assessment and Recommendations for Kids (SPARK), a web-based application designed to facilitate symptom screening by children receiving cancer treatments and access to supportive care clinical practice guidelines primarily by healthcare providers. The objective wa...
journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-018-0715-6
更新日期:2019-01-10 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-019-0804-1
更新日期:2019-04-27 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12911-017-0414-8
更新日期:2017-02-20 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-015-0180-4
更新日期:2015-07-24 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-020-01269-w
更新日期:2020-10-01 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/s12911-020-01367-9
更新日期:2021-01-06 00:00:00
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journal_title:BMC medical informatics and decision making
pub_type: 杂志文章
doi:10.1186/1472-6947-3-9
更新日期:2003-07-08 00:00:00