Enlarged parathyroid glands discovered in normocalcemic patients during thyroid surgery.

Abstract:

BACKGROUND:This is a retrospective study analyzing data of normocalcemic patients with enlarged parathyroid glands discovered during thyroid surgery and comparing it with data of patients operated on for proved primary hyperparathyroidism. METHODS:The records of patients with enlarged parathyroid glands (group 1) and those with primary hyperparathyroidism (group 2) were reviewed. RESULTS:There were 11 patients in group 1 and 123 patients in group 2. Enlarged parathyroid glands identified at thyroid surgery were lighter and developed in younger patients. Biochemistry and pathology revealed that these were less hyperfunctioning. Sex, number of diseased glands per patient, and cell type were not statistically different between the 2 groups. CONCLUSIONS:Enlarged parathyroid glands discovered at the time of surgery are mildly hyperfunctioning. They may represent an early pathologic stage responsible for overt primary hyperparathyroidism. We recommend removal of enlarged parathyroid glands found during thyroid operation in normocalcemic patients as long as at least 1 normal parathyroid gland remains.

journal_name

Am J Surg

authors

Abboud B,Sleilaty G,Braidy C,Ghorra C,Abadjian G,Tohme C,Noun R,Sarkis R

doi

10.1016/j.amjsurg.2007.01.033

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

30-3

issue

1

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(07)00600-9

journal_volume

195

pub_type

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