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Synthesis and biological properties of 4-(3H)-quinazolone derivatives.

Abstract：

:A new quinazolone series has been designed, and synthesized by the anthranilic acid and different acid derivatives. Their structures have been elucidated on the basis of elemental analyses and spectral studies (IR, (1)H NMR, FT-IR and FAB-MS). A preliminary radiolabelling study with technetium has shown a very good future prospect for further evaluation in vivo. The biological activities (antifungal, antibacterial as well as anticancerous) of the evaluated compounds are discussed in this article.

journal_name

Eur J Med Chem

journal_title

European journal of medicinal chemistry

authors

Tiwari AK,Singh VK,Bajpai A,Shukla G,Singh S,Mishra AK

doi

10.1016/j.ejmech.2007.01.002

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

1234-8

issue

9

eissn

0223-5234

issn

1768-3254

pii

S0223-5234(07)00035-9

journal_volume

42

pub_type

杂志文章

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