Abstract：
INTRODUCTION:To examine the trends in the prevalence of breast cancer risk factors in relation to breast cancer incidence trends and to explore whether the changes in risk factors differed by ethnicity in Hawaii over a 25-year period. METHODS:We pooled 17 population-based epidemiological studies conducted in Hawaii between 1975 and 2001. The study population of 82,295 women included subjects of Caucasian, Japanese, Native Hawaiian, Chinese, and Filipino ancestry. We computed age-adjusted prevalence estimates by ethnic group for 5-year time periods. Logistic regression was used to evaluate trends over time. RESULTS:The prevalence of an early age at menarche, nulliparity, and parity of fewer than three children, but not that of a late age at first live birth, increased during the study period. Whereas current smoking decreased for all ethnicities over time, the age-adjusted prevalence of overweight, obesity, college education, and alcohol use increased. Trends differed by ethnicity. For Native Hawaiians, the prevalence of overweight, obesity, alcohol use and nulliparity rose over time. For Japanese, the prevalence of overweight, early age at menarche, and having fewer than three children increased. Caucasians showed an increasing prevalence of overweight, obesity, college education, and nulliparity. In Filipina women, we observed changes in reproductive behavior and increasing obesity. CONCLUSIONS:Despite a slowing trend for some breast cancer risk factors, the overall risk profile in this population may lead to further increases in breast cancer incidence. Different ethnic groups may benefit from specific prevention strategies.
journal_name
Breast Cancer Res Treatjournal_title
Breast cancer research and treatmentauthors
Maskarinec G,Zhang Y,Takata Y,Pagano I,Shumay DM,Goodman MT,Le Marchand L,Nomura AM,Wilkens LR,Kolonel LNdoi
10.1007/s10549-005-9129-0subject
Has Abstractpub_date
2006-07-01 00:00:00pages
45-55issue
1eissn
0167-6806issn
1573-7217journal_volume
98pub_type
杂志文章abstract：:Complete remissions in patients with metastatic breast cancer using endocrine therapy or chemotherapy are infrequent. Breast tumors are known to be heterogeneous with respect to estrogen receptor status, and the low complete remission rate may be related to this biochemical heterogeneity. Based on laboratory experimen...
journal_title：Breast cancer research and treatment
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doi：10.1007/BF01805721
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章
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journal_title：Breast cancer research and treatment
pub_type： 临床试验,杂志文章
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更新日期：1997-01-01 00:00:00
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journal_title：Breast cancer research and treatment
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doi：10.1007/s10549-014-3149-6
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journal_title：Breast cancer research and treatment
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pub_type： 杂志文章,随机对照试验
doi：10.1007/s10549-014-2933-7
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVES:To determine any changes in usage of axillary dissection over time from 1983 to 1993, and to characterize those patients who do not receive axillary node dissection. METHODS:A total of 129,946 female patients receiving cancer-directed surgery for early stage breast cancer, who were identified from the SEER ...
journal_title：Breast cancer research and treatment
pub_type： 杂志文章
doi：10.1023/a:1006170811237
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章,评审
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journal_title：Breast cancer research and treatment
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章
doi：10.1023/b:brea.0000003916.39959.73
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journal_title：Breast cancer research and treatment
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更新日期：2020-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-11-01 00:00:00
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章,meta分析
doi：10.1007/s10549-013-2622-y
更新日期：2013-07-01 00:00:00
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章
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更新日期：2007-09-01 00:00:00
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章
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journal_title：Breast cancer research and treatment
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journal_title：Breast cancer research and treatment
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pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章,多中心研究
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章
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journal_title：Breast cancer research and treatment
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更新日期：2012-01-01 00:00:00
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章
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journal_title：Breast cancer research and treatment
pub_type： 杂志文章
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更新日期：2011-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2017-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：1981-01-01 00:00:00
