Abstract:
:Acne is a multifactorial inflammatory disease affecting pilosebaceous follicles. The initial event in the development of an acne lesion is abnormal desquamation of the keratinocytes that line the sebaceous follicle, which creates a microplug or microcomedo. An increase in circulating androgens at the onset of puberty stimulates the production of sebum into the pilosebaceous unit. These events combine to create an environment within the pilosebaceous unit that is favorable for the colonization of the commensal bacteria, Propionibacterium acnes. With proliferation, P acnes secretes various inflammatory molecules and chemotactic factors that initiate and perpetuate the local inflammatory response and possibly induce keratinocyte hyperproliferation as well.
journal_name
Cutisjournal_title
Cutisauthors
Webster GFsubject
Has Abstractpub_date
2005-08-01 00:00:00pages
4-7issue
2 Suppleissn
0011-4162issn
2326-6929journal_volume
76pub_type
杂志文章相关文献
CUTIS文献大全abstract::Green hair is an unusual dermatologic condition usually due to the deposition of copper from exogenous sources. We report the cases of two patients who presented to our clinic with green discoloration of their hair. This pigmentation of hair has generally been reported in patients with blond hair as a consequence of i...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract::A 96-year-old woman presented with a rapidly enlarging lesion overlying the suprasternal notch. The lesion originated as a small, erythematous, scaly macule that rapidly increased in size over 8 weeks and became an ulcerated nodule measuring 5 cm in diameter and 4.5 cm in thickness. A 4-mm punch biopsy showed a poorly...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2018-04-01 00:00:00
abstract::Since most clinicians and researchers agree that stress affects the course of psoriasis, consideration should be given to advocating adjunctive therapies aimed at reducing psychophysiological stress. Biofeedback training, psychotherapy, and hypnosis are examples of adjuncts to traditional medical treatment that can re...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::Primary apocrine adenocarcinoma (AA) is a rare malignant cutaneous neoplasm that typically arises in areas of high apocrine gland density such as the axillae and the anogenital region. Due to the nonspecific clinical manifestation of AA, the differential diagnosis may be broad. The rarity of this neoplasm has led to a...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2015-05-01 00:00:00
abstract::A 52-year-old woman who had had ulcerative colitis for more than ten years experienced a third relapse of pyoderma gangrenosum of her lower extremities. She was treated with topical disodium cromoglycate. The dosage of salicylazosulfapyridine and steroids she was taking, and by which the ulcerative colitis, but not th...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1988-11-01 00:00:00
abstract::A patient with cheilitis granulomatosa and sialopenia is presented herein as a variant of the oligosymptomatic type of Melkersson-Rosenthal syndrome. Evidence is presented to support its possible neurotrophic origin. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1979-12-01 00:00:00
abstract::Fixed drug eruption (FDE) can be caused by an assortment of drugs. Although cross-sensitivity to 2 chemically related drugs has been frequently described, FDE to 2 unrelated agents rarely has been reported. To our knowledge, we report the first such case due to doxycycline and metronidazole. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract::Nocardia brasiliensis is recognized in the United States as an infectious agent of the skin that may present as an abscess, ulcer, or granuloma with or without "sporotrichoid" spread, and rarely causes systemic disease. Treatment with trimethoprim/sulfamethoxazole is usually curative. We present a patient with multipl...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract::Acquired perforating dermatosis (APD) is characterized by pruritic craterlike lesions with a predilection for patients affected by chronic kidney disease or diabetes mellitus (DM). We present a case of a 57-year-old black woman admitted for chest pain and dyspnea who was found to have 2 teardrop-shaped yellow-white-ch...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2018-10-01 00:00:00
abstract::Hair loss in children can have psychologic effects that interfere with a child's growth and development. In our case series, we evaluated 1003 children aged 0 months to 17 years who presented to the pediatric and dermatology outpatient clinics at Fatih University, Ankara, Turkey, from December 2009 through October 201...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2012-11-01 00:00:00
abstract::We report a case of generalized tuberous xanthoma with type IV hyperlipoproteinemia in a 42-year-old woman who had multiple, grouped, yellowish brown nodules bilaterally on the trunk, knees, elbows, palms, soles, and dorsal sides of multiple interphalangeal joints. On laboratory examination, serum triglyceride levels ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract::Three independent clinical studies were conducted in more than 1250 patients with moderate to moderately severe acne vulgaris to evaluate the efficacy and safety of a new combination gel that stably combines 5% benzoyl peroxide and 1% clindamycin. The results indicated that the benzoyl peroxide/clindamycin combination...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2001-02-01 00:00:00
abstract::An atypical case of pemphigus vulgaris that presented with vesiculobullous pustular lesions on the feet and hands is discussed. The initial clinical diagnosis was dyshidrotic eczema. Other unusual manifestations of pemphigus vulgaris are briefly reviewed. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1985-05-01 00:00:00
abstract::Patients with rosacea form a unique subset of the sensitive skin population because of the barrier defects inherent in this condition and the increased propensity for burning/stinging from topical products. This propensity for burning/ stinging when medications, skin care products, or cosmetics are applied to the faci...
journal_title:Cutis
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-10-01 00:00:00
abstract::A 72-year-old woman presented with a progressively enlarging, painful umbilical nodule. A biopsy specimen of the lesion showed focally mucin-producing adenocarcinoma, and the patient was diagnosed to have metastatic carcinoma of umbilicus: Sister Mary Joseph's nodule. Search for the primary tumor revealed adenocarcino...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract::Scar sarcoidosis refers to lesions of cutaneous sarcoidosis that appear in preexisting scars. This condition may be caused by mechanical trauma such as skin cuts or venipuncture, scars caused by infection such as herpes zoster, and tattoos. We present a case of a 34-year-old man who developed scar sarcoidosis followin...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:2006-12-01 00:00:00
abstract::High-potency topical corticosteroids are the cornerstone of psoriasis therapy. Although highly effective, long-term use of topical steroids can cause adverse side effects. Additionally, steroids alone do not address the multiple pathophysiologic factors that cause the disease. Psoriasis regimens that utilize high-pote...
journal_title:Cutis
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:2011-10-01 00:00:00
abstract::An odontogenic cutaneous sinus tract (OCST) of dental origin is an uncommon and frequently misdiagnosed lesion that is caused by chronic periodontitis. Given that OCSTs often lack symptoms, are located on the lower face, and can have notable variations in clinical appearance, they can be mistaken for more common derma...
journal_title:Cutis
pub_type: 杂志文章
doi:10.12788/cutis.0081
更新日期:2020-10-01 00:00:00
abstract::A new approach to the diagnosis and measurement of the thickness of basal cell epithelioma (BCE) by ultrasonography is described. The advantages and efficacy of the new technique are presented. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1984-11-01 00:00:00
abstract::Fatigue, a substantial symptom of psoriasis, is triggered by complex interactions of inflammation in psoriatic disease, both directly via inflammatory cytokines and indirectly via psychological and physiological factors. We provide data and observations that highlight the importance of qualifying and quantifying fatig...
journal_title:Cutis
pub_type: 杂志文章,评审
doi:
更新日期:2016-02-01 00:00:00
abstract::A 15-year-old woman developed an atrophic band on the anterior aspect of her left thigh. A homolateral tibial cyst had been diagnosed five years earlier. To the best of our knowledge, the association of lipoatrophia semicircularis and osseous cysts has, up to now, been unknown. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1983-04-01 00:00:00
abstract::In summary, then, tazarotene is a selective RAR agonist. It has clinical efficacy similar to fluocinonide cream, but no risk of atrophogenicity, no tachyphylaxis, and longer duration of remission than we see with topical corticosteroids. Adverse effects are erythema, burning, and pruritus. Such effects are reduced and...
journal_title:Cutis
pub_type:
doi:
更新日期:1998-02-01 00:00:00
abstract::Extramammary Paget disease (EMPD) is a malignant tumor typically found in apocrine-rich areas of the skin, particularly in the anogenital region. Some germinative apocrine-differentiating cells might exist on the trunk, preferentially in Asian individuals. Ectopic EMPD arises in nonapocrine-bearing areas, specifically...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2018-06-01 00:00:00
abstract::The treatment of psoriasis with psoralen and direct sunlight has been reported as successful but unpredictable because of its dependence on prevailing weather conditions which are subject to marked daily and seasonal variations. A study carried out in a locale nearly ideal because of its reliable year-round sunshine p...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1979-10-01 00:00:00
abstract::Cytologic examination of epithelial cells from the base of vesicles, virus isolation, and bacterial culture were carried out in thirty-one patients with herpes simplex, in eleven patients with herpes zoster, and in three patients with varicella. Determination of herpes simplex complement fixation reaction was made in ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1978-07-01 00:00:00
abstract::Liquid nitrogen spray followed by light electrodesiccation treatment is helpful in the management of flat warts, small skin tags, seborrheic keratoses, and cherry angiomas. Patients experience minimal discomfort and the procedure can be rapidly completed with excellent cosmetic results. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1985-06-01 00:00:00
abstract::Condom sales rose in the 1980s because condoms protect against the spread of sexually transmitted diseases and AIDS. In anticipation of corresponding increase in the incidence of condom dermatitis, a dermatologist prepared a brief overview of the condition and ways to treat it to prepare health professional for the a...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1987-04-01 00:00:00
abstract::We present a case of eosinophilic fasciitis, or Shulman syndrome, in a 35-year-old man and discuss its clinical and histopathologic aspects, as well as its relationship to scleroderma. Although controversial, the tendency is to set Shulman syndrome apart from all other sclerodermiform states. ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2005-04-01 00:00:00
abstract::A patient with refractory idiopathic thrombocytopenic purpura developed widespread palpable purpura, fever, diarrhea, and arthralgias forty-eight hours following a third protein A immunoadsorption treatment. A skin biopsy revealed leukocytoclastic vasculitis. His skin lesions and constitutional symptoms resolved with ...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:1999-10-01 00:00:00
abstract::Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is an underreported diagnosis in dermatologic literature. Rapid expansion with an ulcerative clinical appearance often provokes fear of malignancy despite its benign nature. Traumatic ulcerative granuloma with stromal eosinophilia is thought to be a reac...
journal_title:Cutis
pub_type: 杂志文章
doi:
更新日期:2017-08-01 00:00:00