Abstract：
:The purpose of this study was to determine the efficacy of diffusion-weighted imaging (DWI) and magnetization transfer imaging (MTI) in the differential diagnosis of brain infarct, infection, hamartoma, and tumor in 106 children. The apparent diffusion coefficients (ADCs) and magnetization transfer ratios (MTRs) of the lesions were compared using nonparametric tests. There was an inverse relationship between ADC and MTR in subacute/chronic infarct, infection, hamartoma, arachnoid cyst, and tumor relative to normal brain parenchyma. Both ADC and MTR were reduced in acute infarct. DWI and MTI had a complementary role in the differential diagnosis of acute infarct from infection with lower MTR, from hamartoma with higher ADC, and from low-grade gliomas and benign tumors that had higher ADCs and lower MTRs. ADCs increased and MTRs decreased with the duration of infarct and lower tumor grade.
journal_name
Clin Imagingjournal_title
Clinical imagingauthors
Pui MH,Wang Ydoi
10.1016/j.clinimag.2004.08.001subject
Has Abstractpub_date
2005-05-01 00:00:00pages
162-71issue
3eissn
0899-7071issn
1873-4499pii
S0899-7071(04)00169-Xjournal_volume
29pub_type
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